Biosynthesis and uptake of thiamine (vitamin B1) in bloodstream form Trypanosoma brucei brucei and interference of the vitamin with melarsen oxide activity

International Journal for Parasitology

Volumn 36, Issue 2, 2006, Pages 229-236

  Stoffel, Sabine A ^a   Rodenko, Boris ^b   Schweingruber, Anne Marie ^a   Mäser, Pascal ^a   De Koning, Harry P ^b   Schweingruber, M Ernst ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Melarsen oxide; Pyridoxine; Thiamine; Thiamine analogues; Thiamine uptake; Trypanosoma brucei

Indexed keywords

AMPROLIUM; MELARSENOXIDE; MELARSOPROL; MEMBRANE PROTEIN; OXYTHIAMINE; PROTEIN P2; PYRIDOXINE; PYRITHIAMINE; THIAMINE;

PARASITOLOGY; TRYPANOSOMIASIS; VITAMIN;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; GENOME ANALYSIS; LYSIS; NONHUMAN; SACCHAROMYCES CEREVISIAE; TRYPANOSOMA BRUCEI; VITAMIN METABOLISM;

ANIMALS; ARSENICALS; HUMANS; MICROBIAL SENSITIVITY TESTS; PARASITEMIA; THIAMINE; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS; VITAMIN B 6;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCES POMBE; SCHIZOSACCHAROMYCES POMBE; TRYPANOSOMA BRUCEI; TRYPANOSOMA BRUCEI BRUCEI;

EID: 32144431759     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2005.10.003     Document Type: Article

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