Characterisation of the mulibrey nanism-associated TRIM37 gene: Transcription initiation, promoter region and alternative splicing

Gene

Volumn 366, Issue 1, 2006, Pages 180-188

  Hämäläinen, Riikka H ^a   Joensuu, Tarja ^a   Kallijärvi, Jukka ^a   Lehesjoki, Anna Elina ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Alternative splicing; Expression; Mulibrey nanism; Promoter; Transcription initiation; TRIM37

Indexed keywords

LUCIFERASE; MESSENGER RNA; NUCLEOTIDE; PHOSPHOPROTEIN PHOSPHATASE 1;

3' UNTRANSLATED REGION; ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CODON; CONTROLLED STUDY; DNA FLANKING REGION; DWARFISM; GENE CONSTRUCT; GENE EXPRESSION; GENE IDENTIFICATION; GENE MAPPING; GENE MUTATION; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REPORTER GENE; STOP CODON; TRANSCRIPTION INITIATION SITE; TRIM37 GENE;

3' UNTRANSLATED REGIONS; ALTERNATIVE SPLICING; CODON, INITIATOR; CODON, TERMINATOR; GENE EXPRESSION REGULATION; HUMANS; MALE; MULIBREY NANISM; NUCLEAR PROTEINS; ORGAN SPECIFICITY; PROMOTER REGIONS (GENETICS); RNA, ANTISENSE; TESTIS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 32044471914     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2005.08.008     Document Type: Article

References (31)

1. C.R. Alonso Nonsense-mediated RNA decay: a molecular system micromanaging individual gene activities and suppressing genomic noise BioEssays 27 2005 463 466
2. K. Avela Gene encoding a new RING-B-box-coiled-coil protein is mutated in mulibrey nanism Nat. Genet. 25 2000 298 301
3. K.E. Baker, and R. Parker Nonsense-mediated mRNA decay: terminating erroneous gene expression Curr. Opin. Cell Biol. 16 2004 293 299
4. K.L. Borden RING domains: master builders of molecular scaffolds? J. Mol. Biol. 295 2000 1103 1112
5. C.H. de Moor, H. Meijer, and S. Lissenden Mechanisms of translational control by the 3′UTR in development and differentiation Semin. Cell Dev. Biol. 16 2005 49 58
6. F. Gebauer, and M.W. Hentze Molecular mechanisms of translational control Nat. Rev., Mol. Cell Biol. 5 2004 827 835
7. Y. Geng, and L.F. Johnson Lack of an initiator element is responsible for multiple transcriptional initiation sites of the TATA-less mouse thymidylate synthase promoter Mol. Cell. Biol. 13 1993 4894 4903
8. R.H. Hämäläinen Novel mutations in the TRIM37 gene in mulibrey nanism Human Mutat. 23 2004 522
9. R.T. Hillman, R.E. Green, and S.E. Brenner An unappreciated role for RNA surveillance Genome Biol. 5 2004 R8
10. P. Jagiello A novel splice site mutation in the TRIM37 gene causes mulibrey nanism in a Turkish family with phenotypic heterogeneity Human Mutat. 21 2003 630 635
11. J. Kallijärvi, K. Avela, M. Lipsanen-Nyman, I. Ulmanen, and A.E. Lehesjoki The TRIM37 gene encodes a peroxisomal RING-B-box-coiled-coil protein: classification of mulibrey nanism as a new peroxisomal disorder Am. J. Hum. Genet. 70 2002 1215 1228
12. J. Kallijärvi, U. Lahtinen, R. Hämäläinen, M. Lipsanen-Nyman, J.J. Palvimo, and A.E. Lehesjoki TRIM37 defective in mulibrey nanism is a novel RING finger ubiquitin E3 ligase Exp. Cell Res. 308 2005 146 155
13. N. Karlberg, H. Jalanko, J. Perheentupa, and M. Lipsanen-Nyman Mulibrey nanism: clinical features and diagnostic criteria J. Med. Genet. 41 2004 92 98
14. C.G. Koh, E.J. Tan, E. Manser, and L. Lim The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family Curr. Biol. 12 2002 317 321
15. S. Kuersten, and E.B. Goodwin The power of the 3′UTR: translational control and development Nat. Rev., Genet. 4 2003 626 637
16. Y.K. Kwon, and N.B. Hecht Cytoplasmic protein binding to highly conserved sequences in the 3′untranslated region of mouse protamine 2 mRNA, a translationally regulated transcript of male germ cells Proc. Natl. Acad. Sci. U. S. A. 88 1991 3584 3588
17. Y.K. Kwon, and N.B. Hecht Binding of a phosphoprotein to the 3′untranslated region of the mouse protamine 2 mRNA temporally represses its translation Mol. Cell. Biol. 13 1993 6547 6557
18. L.F. Lareau, R.E. Green, R.S. Bhatnagar, and S.E. Brenner The evolving roles of alternative splicing Curr. Opin. Struct. Biol. 14 2004 273 282
19. A.E. Lehesjoki, V.A. Reed, R. Mark Gardiner, and N.D. Greene Expression of MUL, a gene encoding a novel RBCC family ring-finger protein, in human and mouse embryogenesis Mech. Dev. 108 2001 221 225
20. B.P. Lewis, R.E. Green, and S.E. Brenner Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans Proc. Natl. Acad. Sci. U. S. A. 100 2003 189 192
21. M. Lipsanen-Nyman Mulibrey Nanismi 1986 University of Helsinki Helsinki, Finland
22. M. Lipsanen-Nyman, J. Perheentupa, J. Rapola, A. Sovijärvi, and M. Kupari Mulibrey heart disease: clinical manifestations, long-term course, and results of pericardiectomy in a series of 49 patients born before 1985 Circulation 107 2003 2810 2815
23. H.P. Luther Role of endogenous antisense RNA in cardiac gene regulation J. Mol. Med. 83 2005 26 32
24. A.D. Medhurst, D.C. Harrison, S.J. Read, C.A. Campbell, M.J. Robbins, and M.N. Pangalos The use of TaqMan RT-PCR assays for semiquantitative analysis of gene expression in CNS tissues and disease models J. Neurosci. Methods 98 2000 9 20
25. J.T. Mendell, N.A. Sharifi, J.L. Meyers, F. Martinez-Murillo, and H.C. Dietz Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise Nat. Genet. 36 2004 1073 1078
26. R. Pero Translational regulation of a novel testis-specific RNF4 transcript Mol. Reprod. Dev. 66 2003 1 7
27. A. Reymond The tripartite motif family identifies cell compartments EMBO J. 20 2001 2140 2151
28. G.A. Reynolds, J.L. Goldstein, and M.S. Brown Multiple mRNAs for 3-hydroxy-3-methylglutaryl coenzyme A reductase determined by multiple transcription initiation sites and intron splicing sites in the 5′-untranslated region J. Biol. Chem. 260 1985 10369 10377
29. S. Stamm Function of alternative splicing Gene 344 2005 1 20
30. C. Vanhee-Brossollet, and C. Vaquero Do natural antisense transcripts make sense in eukaryotes? Gene 211 1998 1 9
31. R. Yelin Widespread occurrence of antisense transcription in the human genome Nat. Biotechnol. 21 2003 379 386