Role of estrogen deficiency in the formation and progression of cerebral aneurysms. Part I: Experimental study of the effect of oophorectomy in rats

Journal of Neurosurgery

Volumn 103, Issue 6, 2005, Pages 1046-1051

  Jamous, Mohammad A ^a   Nagahiro, Shinji ^a   Kitazato, Keiko T ^a   Satomi, Junichiro ^a   Satoh, Koichi ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Cerebral aneurysm; Electron microscopy; Estrogen; Oophorectomy; Rat; Vascular cast

Indexed keywords

ESTRADIOL; GELATINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY LIGATION; ARTICLE; BRAIN ARTERY ANEURYSM; COMMON CAROTID ARTERY; CONTROLLED STUDY; DISEASE COURSE; DISEASE PREDISPOSITION; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ESTROGEN DEFICIENCY; FEMALE; HISTOLOGY; HYPERTENSION; NONHUMAN; OVARIECTOMY; PATHOGENESIS; PRIORITY JOURNAL; RAT; RENAL ARTERY; SCANNING ELECTRON MICROSCOPE; STATISTICAL SIGNIFICANCE;

ANIMALS; BLOOD VESSELS; BRAIN; CAROTID ARTERY, COMMON; CORROSION CASTING; DISEASE PROGRESSION; DISEASE SUSCEPTIBILITY; ESTRADIOL; ESTROGENS; FEMALE; INTRACRANIAL ANEURYSM; LIGATION; MICROSCOPY, ELECTRON, SCANNING; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; RENAL ARTERY;

EID: 32044469208     PISSN: 00223085     EISSN: 00223085     Source Type: Journal    
DOI: 10.3171/jns.2005.103.6.1046     Document Type: Article

References (39)

1. Broderick JP, Brott TG, Duldner JE, Tomsick T, Leach A: Initial and recurrent bleeding are the major causes of death following subarachnoid hemorrhage. Stroke 25:1342-1347, 1994
2. Brouchet L, Krust A, Dupont S, Chambon P, Bayard F, Arnal JF: Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptor-alpha but not estrogen receptor-beta. Circulation 103:423-428
3. Bruno G, Todor R, Lewis I, Chyatte D: Vascular extracellular matrix remodeling in cerebral aneurysms. J Neurosurg 89:431-440, 1998
4. Burleson AC, Turitto VT: Identification of quantifiable hemodynamic factors in the assessment of cerebral aneurysm behavior. On behalf of the Subcommittee on Biorheology of the Scientific and Standardization Committee of the ISTH. Thromb Haemost 76:118-123, 1996
5. Chambliss KL, Shaul PW: Estrogen modulation of endothelial nitric oxide synthase. Endocr Rev 23:665-686, 2002
6. Chambliss KL, Yuhanna IS, Anderson RG, Mendelsohn ME, Shaul PW: ERbeta has nongenomic action in caveolae. Mol Endocrinol 16:938-946, 2002
7. Chambliss KL, Yuhanna IS, Mineo C, Liu P, German Z, Sherman TS, et al: Estrogen receptor alpha and endothelial nitric oxide synthase are organized into a functional signaling module in caveolae. Circ Res 87: E44-E52, 2000
8. Chen B, Wen Y, Wang H, Polan ML: Differences in estrogen modulation of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-1 expression in cultured fibroblasts from continent and incontinent women. Am Am J Obstet Gynecol 189:59-65, 2003
9. Hackett ML, Anderson CS: Health outcomes 1 year after subarachnoid hemorrhage: An international population-based study. The Australian Cooperative Research on Subarachnoid Hemorrhage Study Group. Neurology 55:658-662, 2000
10. Harrison-Bernard LM, Schulman IH, Raij L: Postovariectomy hypertension is linked to increased renal AT1 receptor and salt sensitivity. Hypertension 42:1157-1163, 2003
11. Hashimoto N, Handa H, Hazama F: Experimentally induced cerebral aneurysms in rats: part I. Surg Neurol 10:3-8, 1978
12. Hashimoto N, Handa H, Hazama F: Experimentally induced cerebral aneurysms in rats: part II. Surg Neurol 11:243-246, 1999
13. Hashimoto N, Handa H, Nagata I, Hazama F: Experimentally induced cerebral aneurysms in rats: part V. Relation of hemodynamics in the circle of Willis to formation of aneurysms. Surg Neurol 13:41-45, 1980
14. Hayashi T, Yamada K, Esaki T, Kuzuya M, Satake S, Ishikawa T, et al: estrogen increases endothelial nitric oxide by a receptor-mediated system. Biochem Biophys Res Commun 214:847-855, 1995
15. Inci S, Spetzler RF: Intracranial aneurysms and arterial hypertension: a review and hypothesis. Surg Neurol 53:530-540, 2000
16. Kim C, Cervos-Navarro J, Kikuchi H, Hashimoto N, Hazama F: Alterations in cerebral vessels in experimental animals and their possible relationship to the development of aneurysms. Surg Neurol 38:331-337, 1992
17. Kim SC, Singh M, Huang J, Prestigiacomo CJ, Winfree CJ, Solomon RA, et al: Matrix metalloproteinase-9 in cerebral aneurysms. Neurosurgery 41:642-667, 1997
18. Lametschwandtner A, Lametschwandtner U, Weiger T: Scanning electron microscopy of vascular corrosion casts - technique and applications: updated review. Scanning Microsc 4:889-941, 1990
19. Levesque MJ, Cornhill JF, Nerem RM: Vascular casting. A new method for the study of the arterial endothelium. Atherosclerosis 34:457-467, 1979
20. Martin-McNulty B, Tham DM, da Cunha V, Ho JJ, Wilson DW, Rutledge JC, et al: 17 Beta-estradiol attenuates development of angiotensin II-induced aortic abdominal aneurysm in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 23:1627-1632, 2003
21. Mhurchu CN, Anderson C, Jamrozik K, Hankey G, Dunbabin D: Australasian Cooperative Research on Subarachnoid Hemorrhage Study (ACROSS) Group: hormonal factors and risk of aneurysmal subarachnoid hemorrhage: an international population-based, case-control study. Stroke 32:606-612, 2001
22. Moalli PA, Klingensmith WL, Meyn LA, Zyczynski HM: Regulation of matrix metalloproteinase expression by estrogen in fibroblasts that are derived from the pelvic floor. Am J Obstet Gynecol 187:72-79, 2002
23. Nerem RM, Alexander RW, Chappell DC, Medford RM, Varner SE, Taylor WR: The study of the influence of flow on vascular endothelial biology. Am J Med Sci 316:169-175, 1998
24. Nickenig G, Baumer AT, Grohe C, Kahlert S, Strehlow K, Rosenkranz S, et al: Estrogen modulates AT1 receptor gene expression in vitro and in vivo. Circulation 97:2197-2201, 1998
25. Ostergaard JR, Hog E: Incidence of multiple intracranial aneurysms. Influence of arterial hypertension and gender. J Neurosurg 63:49-55, 1985
26. Pavo I, Laszlo F, Morschl E, Nemcsik J, Berko A, Cox DA, et al: Raloxifene, an oestrogen-receptor modulator, prevents decreased constitutive nitric oxide and vasoconstriction in ovariectomized rats. Eur J Pharmacol 410:101-104, 2000
27. Pedersen AT, Lidegaard O, Kreiner S, Ottesen B: Hormone replacement therapy and risk of non-fatal stroke. Lancet 350:1277-1283, 1997
28. Sarti C, Tuomilehto J, Salomaa V, Sivenius J, Kaarsalo E, Narva EV, et al: Epidemiology of subarachnoid hemorrhage in Finland from 1983 to 1985. Stroke 22:848-853, 1991
29. Schwartz SM, Petitti DB, Siscovick DS, Longstreth WT Jr, Sidney S, Raghunathan TE, et al: Stroke and use of low-dose oral contraceptives in young women: a pooled analysis of two US studies. Stroke 29:2277-2284, 1998
30. Simoncini T, Hafezi-Moghadam A, Brazil DP, Ley K, Chin WW, Liao JK: Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-oH kinase. Nature 407:538-541, 2000
31. Stober T, Sen S, Anstatt T, Freier G, Schimrigk K: Direct evidence of hypertension and the possible role of post-menopause oestrogen deficiency in the pathogenesis of berry aneurysms. J Neurol 232:67-72, 1985
32. Strehlow K, Rotter S, Wassmann S, Adam O, Grohe C, Laufs K, et al: Modulation of antioxidant enzyme expression and function by estrogen. Circ Res 93:170-177, 2003
33. Sumi D, Ignarro LJ: Estrogen-related receptor alpha 1 up-regulates endothelial nitric oxide synthase expression. Proc Natl Acad Sci U S A 100:14451-14456, 2003
34. Tatchum-Talom R, Martel C, Marette A: Influence of estrogen on aortic stiffness and endothelial function in female rats. Am J Physiol Heart Circ Physiol 282:H491-H498, 2002
35. Topper JN, Cai J, Falb D, Gimbrone MA Jr: Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci U S A 93:10417-10422, 1996
36. Varbiro S, Nadasy GL, Monos E, Vajo Z, Acs N, Miklos Z, et al: Effect of ovariectomy and hormone replacement therapy on small artery biomechanics in angiotensin-induced hypertension in rats. J Hypertens 18:1587-1595, 2000
37. Wassmann S, Baumer AT, Strehlow K, van Eickels M, Grohe C, Ahlbory K, et al: Endothelial dysfunction and oxidative stress during estrogen deficiency in spontaneously hypertensive rats. Circulation 103:435-441, 2001
38. Wiebers DO, Whisnant JP, Sundt TM Jr, O'Fallon WM: The significance of unruptured intracranial saccular aneurysms. J Neurosurg 66:23-29, 1987
39. Ziegler T, Silacci P, Harrison VJ, Hayoz D: Nitric oxide synthase expression in endothelial cells exposed to mechanical forces. Hypertension 32:351-355, 1998