Analytical and semipreparative resolution of ranolazine enantiomers by liquid chromatography using polysaccharide chiral stationary phases

Journal of Separation Science

Volumn 29, Issue 1, 2006, Pages 164-171

  Luo, Xingping ^a,b   Zhai, Zongde ^a,b   Wu, Xiaomei ^a,b   Shi, Yanping ^a   Chen, Liren ^a   Li, Yongmin ^a  

^a LANZHOU INSTITUTE OF CHEMICAL PHYSICS   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Circular dichroism; Enantioseparation; Optical rotation; Polysaccharide carbamate phase; Ranolazine; Semipreparative HPLC

Indexed keywords

CHIRAL STATIONARY PHASES; CIRCULAR DICHROISM SPECTROSCOPY; ENANTIOSEPARATION; RANOLAZINE ENANTIOMERS;

METHANOL; MOLECULAR STRUCTURE; OPTICAL ROTATION; PHASE COMPOSITION; PHASE SEPARATION; POLYSACCHARIDES; SOLUBILITY; SYNTHESIS (CHEMICAL);

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

LORAZEPAM; POLYSACCHARIDE; RANOLAZINE;

ACCURACY; ANALYTIC METHOD; ARTICLE; CASE REPORT; CHIRALITY; DRUG STRUCTURE; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID CHROMATOGRAPHY; OPTICAL ROTATION; PRIORITY JOURNAL; STRUCTURE ANALYSIS; VALIDATION PROCESS;

ACETANILIDES; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MOLECULAR STRUCTURE; PIPERAZINES; POLYSACCHARIDES; REPRODUCIBILITY OF RESULTS; STEREOISOMERISM;

EID: 32044433960     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200500174     Document Type: Article

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