Determination of active pharmaceutical ingredients by heteroatom selective detection using inductively coupled plasma mass spectrometry with ultrasonic nebuilization and membrane desolvation sample introduction

Applied Spectroscopy

Volumn 60, Issue 1, 2006, Pages 82-85

  Kwok, Kaho ^a   Carr, John E ^a   Webster, Gregory K ^b   Carnahan, Jon W ^a  

^a NORTHERN ILLINOIS UNIVERSITY   (United States)

^b PFIZER INC   (United States)

Author keywords

Direct solution introduction; Elemental analysis; Heteroatom determination; ICP MS; Inductively coupled plasma mass spectrometry; Membrane desolvation; Pharmaceutical; Ultrasonic nebulization; USNMD

Indexed keywords

INDUCTIVELY COUPLED PLASMA; IONIZATION; MASS SPECTROMETRY; ULTRASONICS; ARGON; CHEMICAL ANALYSIS; CHLORINE; DRUG PRODUCTS; ELECTROMAGNETIC INDUCTION; FLUORINE; INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY; INTERFERENCE SUPPRESSION; ISOTOPES; MASS SPECTROMETERS; PHOSPHORUS; SULFUR;

DIRECT SOLUTION INTRODUCTION; ELEMENTAL ANALYSIS; HETEROATOM DETERMINATION; MEMBRANE DESOLVATION; ULTRASONIC NEBULIZATION; DESOLVATION; DIRECT SOLUTION; HETEROATOMS; ICP-MS; USN-MD;

DRUG PRODUCTS; ULTRASONIC APPLICATIONS;

DRUG; SOLVENT;

ARTICLE; ARTIFICIAL MEMBRANE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; EQUIPMENT; EQUIPMENT DESIGN; EVALUATION; INSTRUMENTATION; LABORATORY DIAGNOSIS; METHODOLOGY; NEBULIZER; ULTRASOUND;

EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; MEMBRANES, ARTIFICIAL; NEBULIZERS AND VAPORIZERS; PHARMACEUTICAL PREPARATIONS; SOLVENTS; SONICATION; SPECIMEN HANDLING; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 31944439038     PISSN: 00037028     EISSN: None     Source Type: Journal    
DOI: 10.1366/000370206775382659     Document Type: Article

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