Antibodies against Gag are diagnostic markers for feline foamy virus infections while Env and Bet reactivity is undetectable in a substantial fraction of infected cats

Virology

Volumn 345, Issue 2, 2006, Pages 502-508

  Romen, Fabian ^a   Pawlita, Michael ^a   Sehr, Peter ^a   Bachmann, Silke ^b   Schröder, Johannes ^b   Lutz, Hans ^c   Löchelt, Martin ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Diagnostic marker; ELISA; Foamy virus; Humoral immunity

Indexed keywords

GAG PROTEIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MEMBRANE PROTEIN; PROTEIN BET; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN;

ANIMAL MODEL; ARTICLE; CAT; ENZYME LINKED IMMUNOSORBENT ASSAY; HOSPITAL ADMISSION; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; SPUMA VIRUS; VIRUS INFECTION;

ANIMALS; ANTIBODIES, VIRAL; BIOLOGICAL MARKERS; CAT DISEASES; CATS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE PRODUCTS, ENV; GENE PRODUCTS, GAG; GENES, GAG; RECOMBINANT PROTEINS; RETROVIRIDAE INFECTIONS; RETROVIRIDAE PROTEINS; SPUMAVIRUS;

ANIMALIA; FELIDAE; FELINE FOAMY VIRUS; HUMAN SPUMARETROVIRUS; SPUMAVIRUS;

EID: 31944437703     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2005.10.022     Document Type: Article

References (32)

1. A. Aguzzi, S. Marino, R. Tschopp, and A. Rethwilm Regulation of expression and pathogenic potential of human foamy virus in vitro and in transgenic mice Curr. Top. Microbiol. Immunol. 206 1996 243 273
2. A. Alke, A. Schwantes, M. Zemba, R.M. Flügel, and M. Löchelt Characterization of the humoral immune response and virus replication in cats experimentally infected with feline foamy virus Virology 275 2000 170 176
3. A. Alke, A. Schwantes, K. Kido, M. Flötenmeyer, R.M. Flügel, and M. Löchelt The bet gene of feline foamy virus is required for virus replication Virology 287 2001 310 320
4. P. Bandecchi, D. Matteucci, F. Baldinotti, G. Guidi, F. Abramo, F. Tozzini, and M. Bendinelli Prevalence of feline immunodeficiency virus and other retroviral infections in sick cats in Italy Vet. Immunol. Immunopathol. 31 1992 337 345
5. S.T. Butera, J. Brown, M.E. Callahan, S.M. Owen, A.L. Matthews, D.D. Weigner, L.E. Chapman, and P.A. Sandstrom Survey of veterinary conference attendees for evidence of zoonotic infection by feline retroviruses J. Am. Vet. Med. Assoc. 217 2000 1475 1479
6. M.J. Daniels, M.C. Golder, O. Jarrett, and D.W. MacDonald Feline viruses in wildcats from Scotland J. Wildl. Dis. 35 1999 121 124
7. V. Geiselhart, P. Bastone, T. Kempf, M. Schnölzer, and M. Löchelt Furin-mediated cleavage of the feline foamy virus Env leader protein J. Virol. 78 2004 13573 13581
8. T. Glaus, R. Hofmann-Lehmann, C. Greene, B. Glaus, C. Wolfensberger, and H. Lutz Seroprevalence of Bartonella henselae infection and correlation with disease status in cats in Switzerland J. Clin. Microbiol. 35 1997 2883 2885
9. H. Hahn, G. Baunach, S. Brautigam, A. Mergia, D. Neumann-Haefelin, M.D. Daniel, M.O. McClure, and A. Rethwilm Reactivity of primate sera to foamy virus Gag and Bet proteins J. Gen. Virol. 75 1994 2635 2644
10. W. Heneine, W.M. Switzer, P. Sandstrom, J. Brown, S. Vedapuri, C.A. Schable, A.S. Khan, N.W. Lerche, M. Schweizer, D. Neumann-Haefelin, L.E. Chapman, and T.M. Folks Identification of a human population infected with simian foamy viruses Nat. Med. 4 1998 403 407
11. W. Heneine, M. Schweizer, P. Sandstrom, and T. Folks Human infection with foamy viruses Curr. Top. Microbiol. Immunol. 277 2003 181 196
12. A.I. Hussain, V. Shanmugam, V.B. Bhullar, B.E. Beer, D. Vallet, A. Gautier-Hion, N.D. Wolfe, W.B. Karesh, A.M. Kilbourn, Z. Tooze, W. Heneine, and W.M. Switzer Screening for simian foamy virus infection by using a combined antigen Western blot assay: evidence for a wide distribution among Old World primates and identification of four new divergent viruses Virology 309 2003 248 257
13. A.S. Khan, J.F. Sears, J. Muller, T.A. Galvin, and M. Shahabuddin Sensitive assays for isolation and detection of simian foamy retroviruses J. Clin. Microbiol. 37 1999 2678 2686
14. D. Lindemann, and P.A. Goepfert The foamy virus envelope glycoproteins Curr. Top. Microbiol. Immunol. 277 2003 111 129
15. M.L. Linial Foamy viruses are unconventional retroviruses J. Virol. 73 1999 1747 1755
16. M. Löchelt Foamy virus transactivation and gene expression Curr. Top. Microbiol. Immunol. 277 2003 27 61
17. M. Löchelt, F. Romen, P. Bastone, H. Muckenfuss, N. Kirchner, Y.B. Kim, U. Truyen, U. Rösler, M. Battenberg, A. Saib, E. Flory, K. Cichutek, and C. Munk The antiretroviral activity of APOBEC3 is inhibited by the foamy virus accessory Bet protein Proc. Natl. Acad. Sci. U.S.A. 102 2005 7982 7987
18. C.D. Meiering, and M.L. Linial Reactivation of a complex retrovirus is controlled by a molecular switch and is inhibited by a viral protein Proc. Natl. Acad. Sci. U.S.A. 99 2002 15130 15135
19. A. Rethwilm The replication strategy of foamy viruses Curr. Top. Microbiol. Immunol. 277 2003 1 26
20. R.A. Russell, H.L. Wiegand, M.D. Moore, A. Schafer, M.O. McClure, and B.R. Cullen Foamy virus Bet proteins function as novel inhibitors of the APOBEC3 family of innate antiretroviral defense factors J. Virol. 79 2005 8724 8731
21. A. Saib, M.H. Koken, P. van der Spek, J. Peries, and H. de The Involvement of a spliced and defective human foamy virus in the establishment of chronic infection J. Virol. 69 1995 5261 5268
22. A. Schwantes, I. Ortlepp, and M. Löchelt Construction and functional characterization of feline foamy virus-based retroviral vectors Virology 301 2002 53 63
23. A. Schwantes, U. Truyen, J. Weikel, C. Weiss, and M. Löchelt Application of chimeric feline foamy virus-based retroviral vectors for the induction of antiviral immunity in cats J. Virol. 77 2003 7830 7842
24. P. Sehr, K. Zumbach, and M. Pawlita A generic capture ELISA for recombinant proteins fused to glutathione S-transferase: validation for HPV serology J. Immunol. Methods 253 2001 153 162
25. P. Sehr, M. Müller, R. Hopfl, A. Widschwendter, and M. Pawlita HPV antibody detection by ELISA with capsid protein L1 fused to glutathione S-transferase J. Virol. Methods 106 2002 61 70
26. T. Wilk, V. Geiselhart, M. Frech, S.D. Fuller, R.M. Flügel, and M. Löchelt Specific interaction of a novel foamy virus Env leader protein with the N-terminal Gag domain J. Virol. 75 2001 7995 8007
27. I. Winkler, J. Bodem, L. Haas, M. Zemba, H. Delius, R. Flower, R.M. Flügel, and M. Löchelt Characterization of the genome of feline foamy virus and its proteins shows distinct features different from those of primate spumaviruses J. Virol. 71 1997 6727 6741
28. I.G. Winkler, M. Löchelt, J.P. Levesque, J. Bodem, R.M. Flügel, and R.L. Flower A rapid streptavidin-capture ELISA specific for the detection of antibodies to feline foamy virus J. Immunol. Methods 207 1997 69 77
29. I.G. Winkler, R.M. Flügel, M. Löchelt, and R.L. Flower Detection and molecular characterisation of feline foamy virus serotypes in naturally infected cats Virology 247 1998 144 151
30. I.G. Winkler, M. Löchelt, and R.L. Flower Epidemiology of feline foamy virus and feline immunodeficiency virus infections in domestic and feral cats: a seroepidemiological study J. Clin. Microbiol. 37 1999 2848 2851
31. N.D. Wolfe, W.M. Switzer, J.K. Carr, V.B. Bhullar, V. Shanmugam, U. Tamoufe, A.T. Prosser, J.N. Torimiro, A. Wright, E. Mpoudi-Ngole, F.E. McCutchan, D.L. Birx, T.M. Folks, D.S. Burke, and W. Heneine Naturally acquired simian retrovirus infections in central African hunters Lancet 363 2004 932 937
32. S. Yamamoto, M. Omura, and H. Hirata Isolation of porcine, canine and feline IgG by affinity chromatography using protein A Vet. Immunol. Immunopathol. 9 1985 195 200