An environmentally benign method for the synthesis of symmetrical N,N′-disubstituted thioureas in a water medium

Phosphorus, Sulfur and Silicon and the Related Elements

Volumn 180, Issue 12, 2005, Pages 2745-2750

  Li, Zheng ^a   Wang, Zhi Yuan ^a   Zhao, Yan Long ^a   Xing, Yu Lin ^a   Zhu, Wei ^a  

^a NORTHWEST NORMAL UNIVERSITY   (China)

Author keywords

Environmentally benign; Microwave irradiation; N,N disubstituted thiourea; PEG 400; Water medium

Indexed keywords

EID: 31544473484     PISSN: 10426507     EISSN: 15635325     Source Type: Journal    
DOI: 10.1080/104265090968082     Document Type: Article

References (14)

1. T. K. Venkatachalam, E. A. Sudbeck, C. Mao, and F. M. Uckun, Bioorg. Med. Chem. Lett., 11, 523 (2001).
2. S. Karakus and S. Rollas, Farmaco, 57, 577 (2002).
3. E. G. Chalina and L. Chakarova, European J. Med. Chem., 33, 975 (1998).
4. (a) Y. Tobe, S. Sasaki, K. Hirose, and K. Naemura, Tetrahedron Lett., 38, 4791 (1997);
5. (b) J. Smith, J. L. Liras, S. E. Schneider, and E. V. Anslyn, J. Org. Chem., 61, 8811 (1996).
6. U. Heinelt, D. Schultheis, S. Jager, M. Lindenmaier, A. Pollex, and H. S. Beckmann, Tetrahedron, 60, 9883 (2004).
7. S. Sharma, Synthesis, 803 (1978).
8. J. Vazquez, S. Bernes, Y. Reyes, M. Moya, P. Sharma, C. Alvarez, and R. Gutierrez, Synthesis, 1955 (2004).
9. (a) N. Yamazaki, F. Higashi, and T. Iguchi, Tetrahedron Lett., 15, 1191 (1974);
10. (b) M. Ballabeni, R. Ballini, F. Bigi, R. Maggi, M. Parrini, G. Predieri, and G. Sartori, J. Org. Chem., 64, 1029 (1999).
11. F. Kurzer and K. Douraghi-Zadeh, Chem. Rev., 67, 107 (1967).
12. Y. Takikawa, N. Inoue, R. Sato, and S. Takizawa, Chem. Lett., 11, 641 (1982).
13. H. A. Staab, Angew. Chem., Int. Ed. Engl., 1, 351 (1962).
14. C. J. Li and T. H. Chan, Organic Reactions in Aqueous Media, (Wiley, Chichester, 1997).