Syntheses of pantolactone and pantothenic acid derivatives as potential lipid regulating agents

Synthetic Communications

Volumn 36, Issue 3, 2006, Pages 365-391

  Oniciu, Daniela C ^a,b   Bell, Roel P L ^c   McCosar, Bruce H ^d   Bisgaier, Charles L ^a   Dasseux, Jean Louis H ^a   Verdijk, Dennis ^c   Relou, Mike ^c   Smith, Dennis ^c   Regeling, Henk ^c   Leemhuis, Frank M C ^c   Ebbers, Eelco J ^c   Mueller, Ralf ^d   Zhang, Lianhao ^d   Pop, Emil ^d   Cramer, Clay T ^a   Goetz, Brian ^a   McKee, Andrew ^a   Pape, Michael E ^a   Krause, Brian R ^a  

^a Esperion Therapeutics Inc   (United States)

^b University of Florida ^*  (United States)

^c Mercachem BV   (Netherlands)

^d Alchem Laboratories Corporation   (United States)

Author keywords

Coenzyme A; Dyslipidemia; Metabolic disorder; Pantolactone; Pantothenic acid

Indexed keywords

2,4 DIHYDROXY 3,3 DIMETHYL N PYRIDIN 3 YLMETHYL BUTYRAMIDE; 2,4 DIHYDROXY N [2 (4 HYDROXY 3,3 DIMETHYL BUTYLCARBAMOYL)ETHYL] 3,3 DIMETHYLBUTYRAMIDE; 2,4 DIHYDROXY N [4 (6 HYDROXY 5,5 DIMETHYLHEXYLOXY) 2,6 DIMETHYLPHENYL] 3,3 DIMETHYLBUTYRAMIDE; 2,4 DIHYDROXY N [4 [4 (2,3,4 TRIS O ACETYL ALPHA DEXTRO XYLOPYRANOSYL)BUTOXY] 2,6 DIMETHYLPHENYL] 3,3 DIMETHYLBUTYRAMIDE; 6 [4 [(2,4 DIHYDROXY 3,3 DIMETHYLBUTANOYL)AMINO] 3,5 DIMETHYLPHENOXY] 2,2 DIMETHYLHEXANOIC ACID; COENZYME A; N (2,6 DIMETHYL 4 PENTYLOXYPHENYL) 2,4 DIHYDROXY 3,3 DIMETHYLBUTYRAMIDE; N 1 [7 [(2,4 DIHYDROXY 3,3 DIMETHYLBUTANOYL)AMINO] 4 OXOHEPTYL] 2,4 DIHYDROXY 3,3 DIMETHYLBUTANAMIDE; N [2 (2,4 DIHYDROXY 3,3 DIMETHYLBUTYRYLAMINO)ETHYL] 2,4 DIHYDROXY 3,3 DIMETHYLBUTYRAMIDE; N [2 [2 (2,4 DIHYDROXY 3,3 DIMETHYLBUTYRYLAMINO)ETHOXY]ETHYL] 2,4 DIHYDROXY 3,3 DIMETHYLBUTYRAMIDE; N [3 (2,4 DIHYDROXY 3,3 DIMETHYLBUTYRYLAMINO) 2 HYDROXYPROPYL] 2,4 DIHYDROXY 3,3 DIMETHYLBUTYRAMIDE; PANTOLACTONE; PANTOTHENIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; DYSLIPIDEMIA; MOLECULAR MIMICRY; STRUCTURE ANALYSIS;

EID: 31544464392     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397910500377545     Document Type: Article

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