Implication of Gβγ proteins and c-SRC tyrosine kinase in parathyroid hormone-induced signal transduction in rat enterocytes

Journal of Endocrinology

Volumn 188, Issue 1, 2006, Pages 69-78

  Gentili, Claudia ^a   Boland, Ricardo ^a   de Boland, Ana Russo ^a  

^a UNIVERSIDAD NACIONAL DEL SUR   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PARATHYROID HORMONE; PARATHYROID HORMONE RECEPTOR; PROTEIN ANTIBODY; PROTEIN SUBUNIT; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE C; STEROID RECEPTOR COACTIVATOR; TRANSCRIPTION FACTOR; TYROSINE; UNCLASSIFIED DRUG; ADENYLATE CYCLASE; CALCIUM; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HORMONAL REGULATION; INTESTINE CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; DRUG EFFECT; DUODENUM; ENZYME ACTIVATION; IMMUNOBLOTTING; METABOLISM; PHOSPHORYLATION; WESTERN BLOTTING; WISTAR RAT;

ADENYLATE CYCLASE; ANIMALS; BLOTTING, WESTERN; CALCIUM; CELLS, CULTURED; DUODENUM; ENTEROCYTES; ENZYME ACTIVATION; GTP-BINDING PROTEINS; IMMUNOBLOTTING; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; PARATHYROID HORMONE; PHOSPHORYLATION; PROTEIN SUBUNITS; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 31544459507     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.1.06397     Document Type: Article

References (58)

1. Andreev J, Galisteo ML, Kranenburg O, Logan SK, Chiu ES, Okigaki M, Cary LA, Moolenaar WH & Schlessinger J 2001 Src and Pyk2 mediate G protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade. Journal of Biological Chemistry 276 20130-20135.
2. Balcueva EA, Wang Q, Hughes H, Kunsch C, Yu Z & Robishaw JD 2000 Human G protein gamma(11) and gamma(14) subtypes define a new functional subclass. Experimental Cell Research 257 310-319.
3. Betty M, Harnish SW, Rhodes KJ & Cockett MI 1998 Distribution of heterotrimeric G-protein beta and gamma subunits in the rat brain. Neuroscience 85 475-486.
4. Bonaccorsi L, Luconi M, Forti G & Baldi E 1995 Tyrosine kinase inhibition reduces the plateau phase of the calcium increase in response to progesterone in human sperm. FEBS Letters 364 83-86.
5. Bradford M 1976 A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72 248-254.
6. Broome MA & Hunter T 1996 Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling. Journal of Biological Chemistry 271 16798-16806.
7. Brown MT & Cooper JA 1996 Regulation, substrates and functions of Src. Biochimica et Biophysica Acta 1287 121-149.
8. Carragher NO, Fincham VJ, Riley D & Frame MC 2001 Cleavage of focal adhesion kinase by different proteases during Src-regulated transformation and apoptosis. Distinct roles for calpain and caspases. Journal of Biological Chemistry 276 4270-4275.
9. Cary LA, Klinghoffer RA, Sachsenmaier C & Cooper JA 2002 Src catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading. Molecular and Cellular Biology 22 2427-2440.
10. Clapham DE & Neer EJ 1997 G protein beta gamma subunits. Annual Review of Pharmacology and Toxicology 37 167-203.
11. DellaRocca G, vanBiesen T, Daaka Y, Luttrell DK, Luttrell LM & Lefkowitz RJ 1997 Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase. Journal of Biological Chemistry 272 19125-19132.
12. Erpel T & Courtneidge SA 1995 Src family protein tyrosine kinases and cellular signal transduction pathways. Current Opinion in Cell Biology 7 176-182.
13. Farndale R, Allan L & Martin R. 1994 Adenylate cyclase and cAMP. In Signal Transduction, a Practical Approach, pp 75-103. Ed G Milligan. Oxford: Oxford University Press.
14. Fleming I, Fisslthaler B & Busse R 1995 Calcium signaling in endothelial cells involves activation of tyrosine kinases and leads to activation of mitogen-activated protein kinases. Circulation Research 76 522-529.
15. Gentili C & de Boland AR 2000 Age-related decline in mitogen-activated protein kinase phosphorylation in PTH-stimulated rat enterocytes. Experimental Gerontology 35 1003-1015.
16. Gentili C, Boland R & de Boland AR 2001a PTH stimulates PLC β and γ isozymes in rat enterocytes: influence of ageing. Cellular Signaling 13 131-138.
17. 2+. Biochimica et Biophysica Acta 1540 201-212.
18. Gentili C, Picotto G, Morelli S, Boland R & Russo de Boland A 2003a Effect of ageing in the early biochemical signals elicited by PTH in intestinal cells. Biochimica et Biophysica Acta 1593 169-178.
19. Gentili C, Morelli S & Russo de Boland A 2003b Characterization of PTH/ PTHrP receptor in rat duodenum: Effects of ageing. Journal of Cellular Biochemistry 88 1157-1167.
20. Hamm HE 1998 The many faces of G protein signalling. Journal of Biological Chemistry 273 669-672.
21. Ibitayo AI, Tsunoda Y, Nozu F, Owyang C & Bitar KN 1998 Src kinase and PI 3-kinase as a transduction pathway in ceramide-induced contraction of colonic smooth muscle. American Journal of Physiology 275 G705-G711.
22. Izbicka E, Niewolna M, Yoneda T, Lowe C, Boyce B & Mundy G 1994 c-Src expression and activity in MG-63 osteoblastic cells modulated by PTH but not required for PTH-mediated adenylate cyclase response. Journal of Bone and Mineral Research 9 127-132.
23. Jamora C, Yamanouye N, Van Lint J, Laudenslager J, Vandenheede JR, Faulkner DJ & Malhotra V 1999 G beta gamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D. Cell 98 59-68.
24. 3 stimulates phospholipase C-gamma in rat colonocytes: role of c-Src in PLC-gamma activation. Journal of Clinical Investigation 99 1831-1841.
25. Koch WJ, Hawes BE, Allen LF & Lefkowitz RJ 1994 Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21 ras. PNAS 91 12706-12710.
26. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 680-685.
27. 2+ entry by tyrosine kinase inhibitors. Journal of Biological Chemistry 268 9945-9948.
28. Liebmann C 2001 Regulation of MAP kinase activity by peptide receptor signaling pathway: paradigms of multiplicity. Cellular Signaling 13 777-785.
29. Lin HC, Duncan JA, Kozasa T & Gilman AG 1998 Sequestration of the G protein beta gamma subunit complex inhibits receptor-mediated endocytosis. PNAS 95 5057-5060.
30. Liu JP, Yajima Y, Li H, Ackland S, Akita Y, Stewart J & Kawashima S 1997 Molecular interactions between dynamin and G-protein beta gamma-subunits in neuroendocrine cells. Molecular and Cellular Endocrinology 132 61-71.
31. Luttrell LM, Hawes BE, van Biesen T, Luttrell DK, Lansing TJ & Lefkowitz RJ 1996 Role of c-Src tyrosine kinase in G protein-coupled receptor- and G beta gamma subunit-mediated activation of mitogen-activated protein kinases. Journal of Biological Chemistry 271 19443-19450.
32. Luttrell LM, Della Rocca GJ, van Biesen T, Luttrell DK & Lefkowitz RJ 1997 G beta gamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation. Journal of Biological Chemistry 272 4637-4644.
33. Ma YC, Huang J, Ali S, Lowry W & Huang XY 2000 Src tyrosine kinase is a novel effector of G protein. Cell 102 635-646.
34. Marinissen MJ & Gutkind JS 2001 G-protein-coupled receptors and signaling networks: emerging paradigms. Trends in Pharmacological Sciences B 22 368-376.
35. Marshall CJ 1995 Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80 179-185.
36. 3 stimulation of calcium uptake by rat intestinal cells involves a dihydropyridine-sensitive cAMP-dependent pathway. Cell Signaling 6 299-304.
37. Massheimer V, Picotto G, Boland R & de Boland AR 2000 Effect of aging on the mechanisms of PTH-induced calcium influx in rat intestinal cells. Journal of Cellular Physiology 182 429-437.
38. Morishita R, Shinohara H, Ueda H, Kato K & Asano T 1999 High expression of the gamma5 isoform of G protein in neuroepithelial cells and its replacement of the gamma2 isoform during neuronal differentiation in the rat brain. Journal of Neurochemistry 73 2369-2374.
39. Neer EJ 1995 Heterotrimeric G proteins: organizers of transmembrane signals. Cell 80 249-257.
40. 2+ elevation and mobilization in T cells. Journal of Biological Chemistry 267 7154-7159.
41. Nishida M, Maruyama Y, Tanaka R, Kontani K, Nagao T & Kurose H 2000 Gαi and Gαo are target proteins of reactive oxygen species. Nature 408 492-495.
42. Parsons JT & Parsons SJ 1997 Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways. Current Opinion in Cell Biology 9 187-192.
43. Picotto G, Massheimer V & Boland R 1997 Parathyroid hormone stimulates calcium influx and the cAMP messenger system in isolated rat duodenal cells. American Journal of Physiology 273 C1349-C1353.
44. Pitcher JA, Inglese J, Higgins JB, Arriza JL, Casey PJ, Kim C, Benovic JL, Kwatra MM, Caron MG & Lefkowitz RJ 1992 Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. Science 257 1264-1267.
45. Rhee SG & Bae YS 1997 Regulation of phosphoinositide-specific phospholipase C isozymes. Journal of Biological Chemistry 272 15045-15048.
46. Roche S, Koegl M, Barone MV, Roussel MF & Courtneidge SA 1995 DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases. Molecular and Cellular Biology 15 1102-1109.
47. Rosenblatt M, Kronenberg H & Potts J 1989 Parathyroid hormone: physiology, chemistry, biosynthesis, secretion, metabolism and mode of action. In Endocrinology, pp 848-891. Ed LJ Degroot. Philadelphia: Saunders.
48. 2+ channels. Trends in Pharmacological Sciences 18 8-11.
49. Schuller U, Lamp EC & Schilling K 2001 Developmental expression of heterotrimeric G-proteins in the murine cerebellar cortex. Histochemistry and Cell Biology 116 149-159.
50. Shah B & Catt KJ 2002 Calcium-independent activation of extracellularly regulated kinases 1 and 2 by angiotensin II in hepatic C9 cells: roles of protein kinase Cdelta, Src/proline-rich tyrosine kinase 2, and epidermal growth receptor trans-activation. Molecular Pharmacology 61 343-351.
51. Snedecor G & Cochran W 1967 Statistical Methods, pp120-134. Ames, Iowa: Iowa State University Press.
52. Stow J & Heimann K 1998 Vesicle budding on Golgi membranes: regulation by G proteins and myosin motors. Biochimica et Biophysica Acta 1404 161-171.
53. Sunahara RK, Dessauer CW & Gilman AG 1996 Complexity and diversity of mammalian adenylyl cyclases. Annual Review of Pharmacology and Toxicology 36 461-480.
54. Tovey KC, Oldham K & Whelam J 1974 A simple direct assay for cyclic AMP in plasma and other biological samples using an improved competitive protein binding technique. Clinica Chimica Acta 56 221-223.
55. 2+-dependent pancreatic enzyme secretion. Biochemical and Biophysical Research Communications 227 876-884.
56. Weiser MM 1973 Intestinal epithelial cell surface membrane glycoprotein synthesis. I. An indicator of cellular differentiation. Journal of Biological Chemistry 248 2536-2541.
57. Xu W, Harrison SC & Eck MJ 1997 Three-dimensional structure of the tyrosine kinase c-Src. Nature 385 595-602.
58. Xu W, Doshi A, Lei M, Eck M & Harrinson S 1999 Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Molecular Cell 3 629-638.