ARTICLE;
CHEMICAL MODIFICATION;
CONTROLLED STUDY;
DRUG ACETYLATION;
DRUG SCREENING;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
POLYMERIZATION;
ROOM TEMPERATURE;
ANTIVIRAL AGENTS;
CELL LINE, TUMOR;
DNA REPLICATION;
HUMANS;
NUCLEOSIDES;
PYRIMIDINES;
Synthesis of acyclic nucleoside phosphonates as antiviral compounds
Wormstadt, F.; Brinckmann, U.; Gutschow, M.; Eger, K. Synthesis of acyclic nucleoside phosphonates as antiviral compounds. J. Heterocycl. Chem. 2000, 37, 1187-1191.
Synthesis and HIV-1 inhibitory properties of new tetrahydrobenzoquinazolinedione and tetrahydrobenzocycloheptenuracil derivatives and of their thioxo analogues
Macchia, M.; Antonelli, G.; Balsamo, A.; Barontini, S.; Calvani, F.; Gentili, D.; Martinelli, A.; Rossello, A.; Turriziani, O.; Tesoro, R. Synthesis and HIV-1 inhibitory properties of new tetrahydrobenzoquinazolinedione and tetrahydrobenzocycloheptenuracil derivatives and of their thioxo analogues. Farmaco 1999, 54(4), 242-247.
Structure-activity relationships among 2-substituted 5,6-dichloro-, 4,6-dichloro-, and 4,5-dichloro-1-[(2-hydroxyethoxy)methyl] and 1-[(1,3-dihydroxy-2-propoxy)methyl]benzimidazoles
Saluja, S.; Zou, R.; Drach, J.C.; Townsend, L.B. Structure-activity relationships among 2-substituted 5,6-dichloro-, 4,6-dichloro-, and 4,5-dichloro-1-[(2-hydroxyethoxy)methyl] and 1-[(1,3-dihydroxy-2-propoxy)methyl] benzimidazoles. J. Med. Chem. 1996, 39(4), 881-891.
(S)-9-(2,3-Dihydroxypropyl)adenine: An aliphatic nucleoside analog with broad-spectrum antiviral activity
De Clercq, E.; Descamps, J.; De Somere, P.; Holy, A. (S)-9-(2,3- Dihydroxypropyl)adenine: an aliphatic nucleoside analog with broad-spectrum antiviral activity. Science 1978, 200, 563-570.
Synthesis of new uracil non-nucleoside derivatives as potential inhibitors of HIV-1
El-Essawy, F.A.; El-Brollosy, N.R.; Pedersen, E.B.; Nielsen, C.J. Synthesis of new uracil non-nucleoside derivatives as potential inhibitors of HIV-1. J. Heterocycl. Chem. 2003, 40, 213-217.
2,4-Diaminothieno[2,3-d]pyrimidines as antifolates and antimalarials. 2. Synthesis of 2,4-diaminopyrido[4′,3′:4,5]thieno[2,3-d]pyrimidines and 2,4-diamino-8H-thiopyrano[4′,3′:4,5]thieno(2,3-d)pyrimidines
Lin Chaykovsky, M.M.; Rosowsky, A.; Modest, J.E. 2,4-Diaminothieno[2,3-d] pyrimidines as antifolates and antimalarials. 2. Synthesis of 2,4-diaminopyrido[4′,3′:4,5]thieno[2,3-d]pyrimidines and 2,4-diamino-8H-thiopyrano[4′,3′:4,5]thieno(2,3-d)pyrimidines. J. Med. Chem. 1973, 16(3), 188-191.
Single-step preparation of condensed 3-(chloroalkyl)pyrimidin-4(3H)-ones from carbo- or heterocyclic 2-aminocarboxylic acid (N-hydroxyalkyl)amides and Vilsmeier reagent. 28. Polycyclic azines with heteroatoms in 1- and 3- positions
Leistner, S.; Silke, V.; Vieweg, H.; Strohscheidt, T. Single-step preparation of condensed 3-(chloroalkyl)pyrimidin-4(3H)-ones from carbo- or heterocyclic 2-aminocarboxylic acid (N-hydroxyalkyl)amides and Vilsmeier reagent. 28. Polycyclic azines with heteroatoms in 1- and 3- positions. Pharmazie 1991, 46(6), 415-418.
Synthesis of thieno[2,3-d]pyridines with an oxalamidic acid or an oxalamidic alkyl ester residue and of 4-alkoxypyrido[3′,2′:4,5] thieno[3,2-d]pyrimidine-2-carboxylic acid derivatives
Wagner, G.; Leistner, S.; Vieweg, H.; Krasselt, U.; Prantz, J. Synthesis of thieno[2,3-d]pyridines with an oxalamidic acid or an oxalamidic alkyl ester residue and of 4-alkoxypyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine-2- carboxylic acid derivatives. Pharmazie 1993, 48(5), 342-346.
Piperazine N-substituted naphthyridines, pyridothienopyrimidines and pyridothienotriazines: New antiprotozoals active against Philasterides dicentrarchi
Quintela, J.M.; Peinador, C.; Gonzalez, L.; Iglesias, R.; Parama, A.; Alvarez, F.; Sanmartin, L.M.; Riguera, R. Piperazine N-substituted naphthyridines, pyridothienopyrimidines and pyridothienotriazines: new antiprotozoals active against Philasterides dicentrarchi. Eur.J. Med. Chem. 2003, 38, 265-275.
Intercalating nucleic acids: The influence of linker length and intercalator type on their duplex stabilities
Christensen, U.B.; Wamberg, M.; El-Essawy, F.A.; Ismail, A.; Nielsen, C.B.; Filichev, V.V.; Jessen, C.H.; Petersen, M.; Pedersen, E.B. Intercalating nucleic acids: the influence of linker length and intercalator type on their duplex stabilities. Nucleosides Nucleotides Nucleic Acids 2004, 23(1,2), 207-238.
Search for a simpler synthetic model system for intramolecular 1,3-dipolar cycloaddition to the 5,6-double bond of a pyrimidine nucleoside
Sasaki, T.; Minamoto, K.; Suzuki, T.; Yamashita, S. Search for a simpler synthetic model system for intramolecular 1,3-dipolar cycloaddition to the 5,6-double bond of a pyrimidine nucleoside. Tetrahedron 1980, 36, 865-870.
