Retrovirus infection and neurological disorders

Clinical Neurology

Volumn 45, Issue 11, 2005, Pages 815-817

  Izumo, Shuji ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

AIDS encephalopathy; HTLV I associated myelopathy (HAM); Neuropathology; Pathogenesis

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; CD8 ANTIGEN; CELL ADHESION MOLECULE; GAMMA INTERFERON; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; APOPTOSIS; BYSTANDER EFFECT; CELL ADHESION; CHRONIC INFLAMMATION; CONFERENCE PAPER; HELPER CELL; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN T CELL LEUKEMIA VIRUS 1; IMMUNE RESPONSE; LYMPHOCYTE MIGRATION; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NEUROPIL; PATHOGENESIS; PROVIRUS; RETROVIRUS INFECTION; SPASTIC PARAPLEGIA; SPINAL CORD BLOOD FLOW; T LYMPHOCYTE;

AIDS DEMENTIA COMPLEX; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; NERVOUS SYSTEM DISEASES; PARAPARESIS, TROPICAL SPASTIC; RETROVIRIDAE INFECTIONS;

EID: 31544445772     PISSN: 0009918X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (10)

1. Izumo S, Umehara F, Osame M: HTLV-I-associated myelopathy. Neuropathology 2000; 20 Suppl: S65-68
2. Umehara F, Izumo S, Nakagawa M, et al: Immunocytochemical analysis of the cellular infiltrate in the spinal cord lesions in HTLV-I-associated myelopathy. J Neuropathol Exp Neurol 1993; 52: 424-430
3. Umehara F, Nakamura A, Izumo S, et al: Apoptosis of T lymphocytes in the spinal cord lesions in HTLV-I-associated myelopathy: a possible mechanism to control viral infection in the central nervous system. J Neuropathol Exp Neurol 1994; 53: 617-624
4. Umehara F, Izumo S, Takeya M, et al: Expression of adhesion molecules and monocyte chemoattractant protein-1 (MCP-1) in the spinal cord lesions in HTLV-I-associated myelopathy. Acta Neuropathol 1996; 91: 343-350
5. Kubota R, Umehara F, Izumo S, et al: HTLV-I proviral DNA mount correlates with infiltrating CD4 + lymphocytes in the spinal cord from patients with HTLV-I-associated myelopathy. J. Neuroimmunol 1994; 53: 23-29
6. Matsuoka E, Takenouchi N, Hashimoto K, et al: Perivascular T cells are infected with HTLV-I in the spinal cord lesions with HTLV-I-associated myelopathy/tropical spastic paraparesis: double staining of immunohistochemistry and polymerase chain reaction in situ hybridization. Acta Neuropathol 1998; 96: 340-346
7. Moritoyo T, Reinhart TA, Moritoyo H, et al: Human T-lymphotropic virus type I-associated myelopathy and tax gene expression in CD4 + T lymphocytes. Ann Neurol 1996; 40: 84-90
8. Takenouchi N, Yamano Y, Usuku K, et al: Usefulness of proviral load measurement for monitoring of disease activity in individual patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis. J Neurovirol 2003; 9: 29-35
9. Aye MM, Matsuoka E, Moritoyo T, et al: Histopathological analysis of four autopsy cases of HTLV-I-associated myelopathy/tropical spastic paraparesis: inflammatory changes occur simultaneously in the entire central nervous system. Acta Neuropathol 2000; 100: 245-252
10. Xing HQ, Moritoyo T, Mori K, et al: Simian immunodeficiency virus encephalitis in the white matter and degeneration of the cerebral cortex occur independently in simian immunodeficiency virus-infected monkey. J Neurovirol 2003; 9: 508-518