Role of intron 5 C/T polymorphism of the calcium sensing receptor gene in the regulation of the serum FSH and LH in post-menopausal women

Journal of Endocrinological Investigation

Volumn 28, Issue 9, 2005, Pages 638-642

  Zofkova I ^a   Zajickova K ^a   Hill, M ^a   Vankova M ^a  

^a INSTITUTE OF ENDOCRINOLOGY   (Czech Republic)

Author keywords

A986S polymorphism; Bone density; Calcium sensing receptor gene; Follicle stimulating hormone; Intron 5 C T polymorphism; Luteinizing hormone

Indexed keywords

CALCIUM SENSING RECEPTOR; FOLLITROPIN; LUTEINIZING HORMONE;

ALLELE; ANALYSIS OF COVARIANCE; ARTICLE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DNA POLYMORPHISM; EXON; FEMALE; FOLLITROPIN BLOOD LEVEL; GENOTYPE; HUMAN; HUMAN EXPERIMENT; INTRON; LUTEINIZING HORMONE BLOOD LEVEL; NUCLEOTIDE SEQUENCE; POSTMENOPAUSE;

EID: 31544437698     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03347263     Document Type: Article

References (25)

1. Brown EM, MacLeod RJ. Extracellular calcium sensing and extracellular calcium signaling. Physiol Rev 2001, 81: 239-97.
2. Emanuel LR, Adler GK, Kifor O, et al. Calcium-sensing receptor expression and regulation by extracellular calcium in the At-T20 pituitary cell line. Mol Endocrinol 1996, 10: 555-65.
3. Cole DE, Peltekova VD, Rubin LA, et al. A986S polymorphism of the calcium-sensing receptor gene and circulating calcium concentrations. Lancet 1999, 353: 112-5.
4. Miedlich S, Lamesch P, Mueller A, Paschke R. Frequency of the calcium-sensing receptor variant A986S in patients with primary hyperparathyroidism. Eur J Endocrinol 2001, 145: 421-7.
5. Cetani F, Borsari S, Vignali E, et al. Calcium-sensing receptor gene polymorphisms in primary hyperparathyroidism. J Endocrinol Invest 2002, 25: 614-9.
6. Koishi S, Aida K, Tawata M, Onaya T. Polymorphism of the human Ca(2+)-sensing receptor gene in Japanese individuals: no relation to non-insulin dependent diabetes mellitus. Norm Metab Res 1996, 28: 541-4.
7. Järvinen TL, Kannus P, Sievänen H. Estrogen and bone - a reproductive and locomotive perspective. J Bone Miner Res 2003, 18: 1921-31.
8. Zofkova I, Hill M, Zajickova K. Dehydroepiandrosterone status in postmenopausal women is determined by the gene for the vitamin D receptor. Horm Metab Res 2002, 34: 127-31.
9. Zofkova I, Zajickova K, Hill M. Postmenopausal serum androstenedione levels are associated with the calcitonin receptor gene polymorphism T1377C. A pilot study. J Endocrinol Invest 2004, 27: 442-4.
10. Maimed S, Kleinberg D. Anterior pituitary. Development, anatomy and overview of control of hormone secretion. In: PR Larsen, HM Kronenberg, S Melmed, KS Polansky eds. Williams Textbook of Endocrinology. Elsevier Science (USA). 2002, 177-81.
11. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucl Acids Res 1988, 16: 1215-9.
12. Yano S, Sugimoto T, Kanzawa M, et al. Association of polymorphic alleles of the calcium-sensing receptor gene with parathyroid hormone secretion in hemodialysis patients. Nephron 2000, 85: 317-23.
13. Lorentzon M, Lorentzon R, Lerner UH, Nordström P. Calcium sensing receptor gene polymorphism, circulating calcium concentrations and bone mineral density in healthy adolescent girls. Eur J Endocrinol 2001, 144: 257-61.
14. th. San Diego: Academic Press, An imprint of Elsevier Inc. 2003, 146-153.
15. 2+-sensing receptor. J Biol Chem 1998, 271: 19537-45.
16. Yamauchi M, Sugimoto T, Yamaguchi T, et al. Association of polymorphic alleles of the calcium-sensing receptor gene with the clinical severity of primary hyperparathyroidism. Clin Endocrinol (Oxf) 2001, 55: 373-9.
17. 2+-sensing receptor coupled to release of intracellular calcium stores. Cell Calcium 1996, 19: 43-57.
18. Emanuel RL, Adler GK, Kifor O, et al. Calcium-sensing receptor expression and regulation by extracellular calcium in the AtT-20 pituitary cell line. Mol Endocrinol 1996, 64: 555-65.
19. Ferry S, Chatel B, Dodd RH, et al. Effects of divalent cations and of a calcimimetic on adrenocorticotropic hormone release in pituitary tumor cells. Biochem Biophys Res Commun 1997, 238: 866-73.
20. Veldhuis JD, Borgis JL, Drake CR, Rogol AD. Divergent influences of calcium ions on releasing factor-stimulated anterior pituitary hormone secretion in normal man. J Clin Endocrinol Metab 1984, 59: 56-61.
21. Bates MD, Conn PM. Calcium mobilization in the pituitary gonadotrope: relative roles of intra- and extracellular sources. Endocrinology 1984, 115: 1380-5.
22. 2+ channels and their role in the endocrine function of the pituitary gland in newborn and adult mice. J Physiol 2004, 555: 769-82.
23. Cetani F, Pardi E, Borsari S, et al. Calcium-sensing receptor gene polymorphism is not associated with bone mineral density in Italian postmenopausal women. Eur J Endocrinology 2003, 148: 603-7.
24. Rubin LA, Peltekova V, Janicic N,et al. Calcium sensing receptor gene: analysis of polymorphism frequency. Scand J Clin Lab Invest 1997, 57: 122-5.
25. Takacs I, Speer G, Bajnok E, et al. Lack of association between calcium-sensing receptor gene "A896S" polymorphism and Hungarian postmenopausal bone mineral density in women. Bone 2002, 30: 849-52.