Is glutamine effective in enhancing host immune response to tumors?

Journal of Nutrition

Volumn 135, Issue 12, 2005, Pages

  Klimberg, V Suzanne ^a  

^a UNIVERSITY OF ARKANSAS   (United States)

Author keywords

Breast cancer; Glutamine; Glutathione; NK cells

Indexed keywords

GLUTAMINE; GLUTATHIONE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53;

BREAST CARCINOMA; CANCER MODEL; CARCINOGENESIS; CELL ACTIVITY; CELL FUNCTION; CONFERENCE PAPER; CYTOLYSIS; DISEASE COURSE; IMMUNE RESPONSE; NATURAL KILLER CELL; NONHUMAN; OXIDATION REDUCTION REACTION; PROTEIN FUNCTION; SARCOMA; T LYMPHOCYTE; TUMOR GROWTH; TUMOR IMMUNITY;

ANIMALIA;

EID: 31544435437     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/135.12.2920s     Document Type: Conference Paper

References (6)

1. Todorova VK, Harms SA, Kaufmann Y, Luo S, Luo KQ, Babb K, Klimberg VS. Effect of dietary glutamine on tumor glutathione levels and apoptosis-related proteins in DMBA-induced breast cancer of rats. Breast Cancer Res Treat. 2004;88(3):247-56.
2. Todorova VK, Harms SA, Luo S, Kaufman Y, Babb KB, Klimberg VS. Oral glutamine (AES-14) supplementation inhibits PI-3k/Akt signaling in experimental breast cancer. J Parenter Enteral Nutr. 2003;27(6):404 -10.
3. Johnson AT, Kaufmann YC, Luo S, Todorova V, Klimberg VS. Effect of glutamine on glutathione, IGF-I, and TGF-beta 1. J Surg Res. 2003;111(2):222-8.
4. Klimberg VS, Kornbluth J, Cao Y, Dang A, Blossom S, Schaeffer RF. Glutamine suppresses PGE2 synthesis and breast cancer growth. J Surg Res. 1996;63(1):293-7.
5. Kaufmann Y, Kornbluth J, Feng Z, Fahr M, Schaeffer RF, Klimberg VS. Effect of glutamine on the initiation and promotion phases of DMBA-induced mammary tumor development. J Parenter Enteral Nutr. 2003;27(6):411-8.
6. Fahr MJ, Kornbluth J, Blossom S, Schaeffer R, Klimberg VS. Harry M Vars Research Award. Glutamine enhances immunoregulation of tumor growth. J Parenter Enteral Nutr. 1994;18(6):471-6.