메뉴 건너뛰기




Volumn 26, Issue 2, 2006, Pages 153-160

Oxidative metabolism in cultured rat astroglia: Effects of reducing the glucose concentration in the culture medium and of D-aspartate or potassium stimulation

Author keywords

Brain energy metabolism; Lactate; Pyruvate

Indexed keywords

CARBON 14; CARBON DIOXIDE; DEOXYGLUCOSE; DEXTRO ASPARTIC ACID; LACTIC ACID; POTASSIUM ION;

EID: 31444438575     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600175     Document Type: Article
Times cited : (64)

References (27)
  • 1
    • 0037025115 scopus 로고    scopus 로고
    • Reduction of Alamar Blue, a novel redox indicator, is dependent on both the glycolytic and oxidative metabolism of glucose in rat cultured neurons
    • Abe T, Takahashi S, Fukuuchi Y (2002) Reduction of Alamar Blue, a novel redox indicator, is dependent on both the glycolytic and oxidative metabolism of glucose in rat cultured neurons. Neurosci Lett 326:179-82
    • (2002) Neurosci Lett , vol.326 , pp. 179-182
    • Abe, T.1    Takahashi, S.2    Fukuuchi, Y.3
  • 2
    • 0021995591 scopus 로고
    • Determinants of deoxyglucose uptake in cultured astrocytes: The role of the sodium pump
    • Brookes N, Yarowsky PJ (1985) Determinants of deoxyglucose uptake in cultured astrocytes: the role of the sodium pump. J Neurochem 44:473-9
    • (1985) J Neurochem , vol.44 , pp. 473-479
    • Brookes, N.1    Yarowsky, P.J.2
  • 3
    • 0242574396 scopus 로고    scopus 로고
    • Energy substrates for neurons during neural activity: A critical review of the astrocyte-neuron lactate shuttle hypothesis
    • Chih CP, Roberts EL, Jr (2003) Energy substrates for neurons during neural activity: a critical review of the astrocyte-neuron lactate shuttle hypothesis. J Cereb Blood Flow Metab 23:1263-81
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 1263-1281
    • Chih, C.P.1    Roberts Jr., E.L.2
  • 4
    • 0000202516 scopus 로고    scopus 로고
    • Circulation and energy metabolism of the brain
    • (Siegel GJ, Agranoff BW, Albers RW, Fisher SK, Uhler MD, eds), New York: Lippincott-Raven
    • Clarke DD, Sokoloff L (1999) Circulation and energy metabolism of the brain. In: Basic neurochemistry: molecular, cellular, and medical aspects. 6th ed. (Siegel GJ, Agranoff BW, Albers RW, Fisher SK, Uhler MD, eds), New York: Lippincott-Raven, 637-69
    • (1999) Basic Neurochemistry: Molecular, Cellular, and Medical Aspects. 6th Ed. , pp. 637-669
    • Clarke, D.D.1    Sokoloff, L.2
  • 5
    • 0037727912 scopus 로고    scopus 로고
    • Neighborly interactions of metabolically-activated astrocytes in vivo
    • Dienel GA, Cruz NF (2003) Neighborly interactions of metabolically- activated astrocytes in vivo. Neurochem Int 43:339-54
    • (2003) Neurochem Int , vol.43 , pp. 339-354
    • Dienel, G.A.1    Cruz, N.F.2
  • 6
    • 2442532184 scopus 로고    scopus 로고
    • Nutrition during brain activation: Does cell-to-cell lactate shuttling contribute significantly to sweet and sour food for thought?
    • Dienel GA, Cruz NF (2004) Nutrition during brain activation: does cell-to-cell lactate shuttling contribute significantly to sweet and sour food for thought? Neurochem Int 45:321-51
    • (2004) Neurochem Int , vol.45 , pp. 321-351
    • Dienel, G.A.1    Cruz, N.F.2
  • 7
    • 8344272718 scopus 로고    scopus 로고
    • The astrocyte-neuron lactate shuttle: A challenge of a challenge
    • Hertz L (2004) The astrocyte-neuron lactate shuttle: a challenge of a challenge. J Cereb Blood Flow Metab 24:1241-8
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 1241-1248
    • Hertz, L.1
  • 8
    • 0032468697 scopus 로고    scopus 로고
    • Functional studies in cultured astrocytes
    • Hertz L, Peng L, Lai JC (1998a) Functional studies in cultured astrocytes. Methods 16:293-310
    • (1998) Methods , vol.16 , pp. 293-310
    • Hertz, L.1    Peng, L.2    Lai, J.C.3
  • 9
    • 0031763269 scopus 로고    scopus 로고
    • Can experimental conditions explain the discrepancy overglutamate stimulation of aerobic glycolysis?
    • Hertz L, Swanson RA, Newman GC, Marrif H, Juurlink BH, Peng L (1998b) Can experimental conditions explain the discrepancy overglutamate stimulation of aerobic glycolysis? Dev Neurosci 20:339-47
    • (1998) Dev Neurosci , vol.20 , pp. 339-347
    • Hertz, L.1    Swanson, R.A.2    Newman, G.C.3    Marrif, H.4    Juurlink, B.H.5    Peng, L.6
  • 10
    • 4544316033 scopus 로고    scopus 로고
    • Fluorometric determination of glucose utilization in neurons in vitro and in vivo
    • Itoh Y, Abe T, Takaoka R, Tanahashi N (2004) Fluorometric determination of glucose utilization in neurons in vitro and in vivo. J Cereb Blood Flow Metab 24:993-1003
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 993-1003
    • Itoh, Y.1    Abe, T.2    Takaoka, R.3    Tanahashi, N.4
  • 11
    • 0037446874 scopus 로고    scopus 로고
    • Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo
    • Itoh Y, Esaki T, Shimoji K, Cook M, Law MJ, Kaufman E, Sokoloff L (2003) Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo. Proc Natl Acad Sci USA 100:4879-84
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4879-4884
    • Itoh, Y.1    Esaki, T.2    Shimoji, K.3    Cook, M.4    Law, M.J.5    Kaufman, E.6    Sokoloff, L.7
  • 13
    • 0035576881 scopus 로고    scopus 로고
    • Alpha-cyano-4-hydroxycinnamate decreases both glucose and lactate metabolism in neurons and astrocytes: Implications for lactate as an energy substrate for neurons
    • McKenna MC, Hopkins IB, Carey A (2001) Alpha-cyano-4-hydroxycinnamate decreases both glucose and lactate metabolism in neurons and astrocytes: implications for lactate as an energy substrate for neurons. J Neurosci Res 66:747-54
    • (2001) J Neurosci Res , vol.66 , pp. 747-754
    • McKenna, M.C.1    Hopkins, I.B.2    Carey, A.3
  • 14
    • 0032900831 scopus 로고    scopus 로고
    • Extracellular glucose concentrations in the rat hippocampus measured by zero-netflux: Effects of microdialysis flow rate, strain, and age
    • McNay EC, Gold PE (1999) Extracellular glucose concentrations in the rat hippocampus measured by zero-netflux: effects of microdialysis flow rate, strain, and age. J Neurochem 72:785-90
    • (1999) J Neurochem , vol.72 , pp. 785-790
    • McNay, E.C.1    Gold, P.E.2
  • 16
    • 0035108931 scopus 로고    scopus 로고
    • Effects of L-glutamate, D-aspartate, and monensin on glycolytic and oxidative glucose metabolism in mouse astrocyte cultures: Further evidence that glutamate uptake is metabolically driven by oxidative metabolism
    • Peng L, Swanson RA, Hertz L (2001) Effects of L-glutamate, D-aspartate, and monensin on glycolytic and oxidative glucose metabolism in mouse astrocyte cultures: further evidence that glutamate uptake is metabolically driven by oxidative metabolism. Neurochem Int 38:437-43
    • (2001) Neurochem Int , vol.38 , pp. 437-443
    • Peng, L.1    Swanson, R.A.2    Hertz, L.3
  • 17
    • 0028046768 scopus 로고
    • High extracellular potassium concentrations stimulate oxidative metabolism in a glutamatergic neuronal culture and glycolysis in cultured astrocytes but have no stimulatory effect in a GABAergic neuronal culture
    • Peng L, Zhang X, Hertz L (1994) High extracellular potassium concentrations stimulate oxidative metabolism in a glutamatergic neuronal culture and glycolysis in cultured astrocytes but have no stimulatory effect in a GABAergic neuronal culture. Brain Res 663:168-72
    • (1994) Brain Res , vol.663 , pp. 168-172
    • Peng, L.1    Zhang, X.2    Hertz, L.3
  • 18
    • 0020071961 scopus 로고
    • Significance of the potassium signal from neurones to glial cells
    • Pentreath VW, Kai-Kai MA (1982) Significance of the potassium signal from neurones to glial cells. Nature 295:59-61
    • (1982) Nature , vol.295 , pp. 59-61
    • Pentreath, V.W.1    Kai-Kai, M.A.2
  • 22
    • 0025950483 scopus 로고
    • Characterization of the glycogenolysis elicited by vasoactive intestinal peptide, noradrenaline and adenosine in primary cultures of mouse cerebral cortical astrocytes
    • Sorg O, Magistretti PJ (1991) Characterization of the glycogenolysis elicited by vasoactive intestinal peptide, noradrenaline and adenosine in primary cultures of mouse cerebral cortical astrocytes. Brain Res 563:227-33
    • (1991) Brain Res , vol.563 , pp. 227-233
    • Sorg, O.1    Magistretti, P.J.2
  • 23
    • 0036161924 scopus 로고    scopus 로고
    • Substrate-dependence of reduction of MTT: A tetrazolium dye differs in cultured astroglia and neurons
    • Takahashi S, Abe T, Gotoh J, Fukuuchi Y (2002) Substrate-dependence of reduction of MTT: a tetrazolium dye differs in cultured astroglia and neurons. Neurochem Int 40:441-8
    • (2002) Neurochem Int , vol.40 , pp. 441-448
    • Takahashi, S.1    Abe, T.2    Gotoh, J.3    Fukuuchi, Y.4
  • 24
    • 0029073149 scopus 로고
    • Role of sodium and potassium ions in regulation of glucose metabolism in cultured astroglia
    • Takahashi S, Driscoll BF, Law MJ, Sokoloff L (1995) Role of sodium and potassium ions in regulation of glucose metabolism in cultured astroglia. Proc Natl Acad Sci USA 92:4616-20
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4616-4620
    • Takahashi, S.1    Driscoll, B.F.2    Law, M.J.3    Sokoloff, L.4
  • 25
    • 0027385413 scopus 로고
    • Regulation of lactate metabolism by albumin in rat neurons and astrocytes from primary culture
    • Vicario C, Tabernero A, Medina JM (1993) Regulation of lactate metabolism by albumin in rat neurons and astrocytes from primary culture. Pediatr Res 34:709-15
    • (1993) Pediatr Res , vol.34 , pp. 709-715
    • Vicario, C.1    Tabernero, A.2    Medina, J.M.3
  • 26
    • 0842344387 scopus 로고    scopus 로고
    • Astrocytes and synaptosomes transport and metabolize lactate and acetate differently
    • Waniewski RA, Martin DL (2004) Astrocytes and synaptosomes transport and metabolize lactate and acetate differently. Neurochem Res 29:209-17
    • (2004) Neurochem Res , vol.29 , pp. 209-217
    • Waniewski, R.A.1    Martin, D.L.2
  • 27
    • 0020697189 scopus 로고
    • The mammalian pyruvate dehydrogenase complex: Structure and regulation
    • Wieland OH (1983) The mammalian pyruvate dehydrogenase complex: structure and regulation. Rev Physiol Biochem Pharmacol 96:123-70
    • (1983) Rev Physiol Biochem Pharmacol , vol.96 , pp. 123-170
    • Wieland, O.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.