Is human Type 2 diabetes maternally inherited? Insights from an animal model

Diabetic Medicine

Volumn 21, Issue 7, 2004, Pages 759-762

  Gill Randall, R J ^a   Adams, D ^a   Ollerton, R L ^b   Alcolado, J C ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF WESTERN SYDNEY   (Australia)

Author keywords

Diabetes mellitus; Inheritance; Rodent

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD GLUCOSE MONITORING; BODY WEIGHT; CONTROLLED STUDY; DIET RESTRICTION; EXTRACHROMOSOMAL INHERITANCE; FEMALE; GLUCOSE BLOOD LEVEL; INTRAVENOUS GLUCOSE TOLERANCE TEST; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROGENY; RAT; RAT STRAIN; SEX DIFFERENCE; SEX RATIO;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GLUCOSE TOLERANCE TEST; HUMANS; LITTER SIZE; MALE; MOTHERS; RATS; RATS, WISTAR; SEX FACTORS;

EID: 3142736018     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1464-5491.2004.01225.x     Document Type: Article

References (12)

1. Alcolado JC, Alcolado R. Importance of maternal history of non-insulin dependent diabetic patients. Br Med J 1991; 302: 1178-1180.
2. Alcolado JC, Laji K, Gill-Randall R. Maternal transmission of diabetes. Diabetic Med 2002; 19: 89-98.
3. Meigs JB, Cupples A, Wilson PWF. Parental transmission of Type 2 diabetes; the Framingham offspring study. Diabetes 2000; 49: 2201-2207.
4. McCarthy M, Cassall P, Tran T, Mathias L, Hart LM, Maassen JA et al. Evaluation of the importance of maternal history of diabetes and mitochondrial variation in the development of NIDDM. Diabetic Med 1996; 13: 420-428.
5. Goto Y, Kakizaki M, Musaki N. Production of spontaneous diabetic rats by repetition of selective breeding. Tohoku J Exp Med 1976; 119: 85-90.
6. Goto Y, Suzuki K, Ono T, Sasaki M, Toyota T. Development of diabetes in the non-obese NIDDM rat (GK rat). Adv Exp Med Biol 1988; 246: 29-31.
7. Gauguier D, Nelson I, Barnard C, Parent V, Marsac C, Cohen D et al. Higher maternal than paternal inheritance of diabetes in GK rats. Diabetes 1994; 43: 220-224.
8. Abdel-Halim SM, Guenifi A, Luthman H, Grill V, Efendic S, Ostenson CG. Impact of diabetic inheritance on glucose tolerance and insulin secretion in spontaneously diabetic GK-Wistar rats. Diabetes 1994; 43: 281-8.
9. Galli J, Li LS, Glaser A, Ostenson CG, Jiao H, Fakhrai-Rad H et al. Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat. Nature Genet 1996; 12: 31-37.
10. Bassett DR, Graig BW. Influence of early nutrition on growth and adipose tissue characteristics in male and female rats. Am J Physiol 1988; 64: 1249-1256.
11. Plagemann A, Harder T, Rake A, Voits M, Fink H, Rohde W et al. Perinatal increase of hypothalamic insulin, acquired malformation of hypothalamic galaninergic neurones, and syndrome X-like alterations in adulthood of neonatally overfed rats. Brain Res 1999; 836: 146-155.
12. Plagemann A, Harder T, Franke K, Kohlhoff R. Long-term impact of neonatal breast-feeding on body weight and glucose tolerance in children of diabetic mothers. Diabetes Care 2002; 25: 16-22.