Enantioselective alkynylation of aldehydes catalyzed by [2.2]paracyclophane-based ligands

Organic Letters

Volumn 6, Issue 13, 2004, Pages 2113-2116

  Dahmen, Stefan ^a  

^a CYNORA GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHANE DERIVATIVE; LIGAND;

ADDITION REACTION; ALKYNYLATION; ARTICLE; CATALYSIS; CHIRALITY; ENANTIOSELECTIVITY; EVALUATION; LIGAND BINDING; SCREENING;

EID: 3142722640     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol049596b     Document Type: Article

References (16)

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15. This behavior is atypical for mixed zinc species. The equilibrium could be influenced by the very low solubility of the dialkynylzinc reagents.
16. Clear supernant solution gives rise to the ethylation product in >80% yield.