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Generation of a spacing pattern: The role of TRIPTYCHON in trichome patterning in Arabidopsis
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The control of trichome spacing and number in Arabidopsis
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Larkin J.C., Prigge M., Marks M.D. The control of trichome spacing and number in Arabidopsis. Development. 122:1996;997-1005
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Clonal relationships and cell patterning in the root epidermis of Arabidopsis
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Dolan L., Duckett C.M., Grierson C., Linstead P., Schneider K., Lawson E., Dean C., Poethig S., Roberts K. Clonal relationships and cell patterning in the root epidermis of Arabidopsis. Development. 120:1994;2465-2474
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Roberts, K.9
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Positional information in root eidermis is defined during embryogenesis and acts in domains with strict boundaries
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Berger F., Haseloff J., Schiefelbein J., Dolan L. Positional information in root eidermis is defined during embryogenesis and acts in domains with strict boundaries. Curr Biol. 8:1998;421-430
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Berger, F.1
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How do cells know what they want to be when they grow up? Lessons from epidermal patterning in Arabidopsis
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Larkin J.C., Brown M.L., Schiefelbein J. How do cells know what they want to be when they grow up? Lessons from epidermal patterning in Arabidopsis. Annu Rev Plant Biol. 54:2003;403-430
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The homeobox gene GLABRA 2 is required for position-dependent cell differentiation in the root epidermis of Arabidopsis thaliana
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Masucci J.D., Rerie W.G., Foreman D.R., Zhang M., Galway M.E., Marks M.D., Schiefelbein J.W. The homeobox gene GLABRA 2 is required for position-dependent cell differentiation in the root epidermis of Arabidopsis thaliana. Development. 122:1996;1253-1260
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Masucci, J.D.1
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Control of GL2 expression in Arabidopsis leaves and trichomes
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Szymanski D.B., Jilk R.A., Pollock S.M., Marks M.D. Control of GL2 expression in Arabidopsis leaves and trichomes. Development. 125:1998;1161-1171
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Szymanski, D.B.1
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The glabra 2 gene encodes a homeo domain protein required for normal trichome development in Arabidobsis
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Rerie W.G., Feldmann K.A., Marks M.D. The glabra 2 gene encodes a homeo domain protein required for normal trichome development in Arabidobsis. Genes Dev. 8:1994;1388-1399
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The Arabidopsis Athb-10 (GLABRA2) is an HD-Zip protein required for regulation of root hair development
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Cristina M.D., Sessa G., Dolan L., Linstead P., Ruberti S., Morelli G. The Arabidopsis Athb-10 (GLABRA2) is an HD-Zip protein required for regulation of root hair development. Plant J. 10:1996;393-402
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11
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0038442830
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Modulation of phospholipid signaling by GLABRA2 in root-hair pattern formation
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The authors demonstrate that the phospholipase Dζ1 gene is controlled by GL2 and that phospholipid signaling is important for root hair development. This is the first description of a link between the patterning machinery and downstream genes controlling the actual differentiation processes.
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Ohashi Y., Oka A., Rodrigues-Pousada R., Possenti M., Ruberti I., Morelli G., Aoyama T. Modulation of phospholipid signaling by GLABRA2 in root-hair pattern formation. Science. 300:2003;1427-1430 The authors demonstrate that the phospholipase Dζ1 gene is controlled by GL2 and that phospholipid signaling is important for root hair development. This is the first description of a link between the patterning machinery and downstream genes controlling the actual differentiation processes.
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Science
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Ohashi, Y.1
Oka, A.2
Rodrigues-Pousada, R.3
Possenti, M.4
Ruberti, I.5
Morelli, G.6
Aoyama, T.7
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WEREWOLF, a MYB-related protein in Arabidopsis, is a position-dependent regulator of epidermal cell patterning
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Lee M.M., Schiefelbein J. WEREWOLF, a MYB-related protein in Arabidopsis, is a position-dependent regulator of epidermal cell patterning. Cell. 99:1999;473-483
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Lee, M.M.1
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A myb gene required for leaf trichome differentiation in Arabiopsis is expressed in stipules
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Oppenheimer D.G., Herman P.L., Sivakumaran S., Esch J., Marks M.D. A myb gene required for leaf trichome differentiation in Arabiopsis is expressed in stipules. Cell. 67:1991;483-493
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Lee M.M., Schiefelbein J. Developmentally distinct MYB genes encode functionally equivalent proteins in Arabidopsis. Development. 128:2001;1539-1546
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Lee, M.M.1
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GL3 encodes a bHLH protein that regulates trichome development in Arabidopsis through interaction with GL1 and TTG1
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Payne C.T., Zhang F., Lloyd A.M. GL3 encodes a bHLH protein that regulates trichome development in Arabidopsis through interaction with GL1 and TTG1. Genetics. 156:2000;1349-1362
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Payne, C.T.1
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The bHLH genes GLABRA3 (GL3) and ENHANCER of GLABRA3 (EGL3) specify epidermal cell fate in the Arabidopsis root
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The authors show that GL3 and EGL3 act together in regulating the non-root hair fate in a redundant manner. Furthermore, the interactions with the other known root hair patterning genes GL2, CPC and WER are analyzed genetically and in yeast two hybrid studies.
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Bernhardt C., Lee M.M., Gonzalez A., Zhang F., Lloyd A., Schiefelbein J. The bHLH genes GLABRA3 (GL3) and ENHANCER OF GLABRA3 (EGL3) specify epidermal cell fate in the Arabidopsis root. Development. 130:2003;6431-6439 The authors show that GL3 and EGL3 act together in regulating the non-root hair fate in a redundant manner. Furthermore, the interactions with the other known root hair patterning genes GL2, CPC and WER are analyzed genetically and in yeast two hybrid studies.
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Development
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Bernhardt, C.1
Lee, M.M.2
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A network of redundant bHLH proteins functions in all TTG1-dependent pathways of Arabidopsis
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It is shown here that the multiple functions of TTG1 in root hair, trichome and anthocyanin biosynthesis are mediated by three bHLH genes - GL3, EGL3 and TT8 - the function of which are partially redundant. For the understanding of trichome patterning, it was very important to uncover the redundant function of GL3 and EGL3.
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Zhang F., Gonzalez A., Zhao M., Payne C.T., Lloyd A. A network of redundant bHLH proteins functions in all TTG1-dependent pathways of Arabidopsis. Development. 130:2003;4859-4869 It is shown here that the multiple functions of TTG1 in root hair, trichome and anthocyanin biosynthesis are mediated by three bHLH genes - GL3, EGL3 and TT8 - the function of which are partially redundant. For the understanding of trichome patterning, it was very important to uncover the redundant function of GL3 and EGL3.
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Development
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Zhang, F.1
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The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in Arabidopsis, encodes a WD40 repeat protein
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Walker A.R., Davison P.A., Bolognesi-Winfield A.C., James C.M., Srinivasan N., Blundell T.L., Esch J.J., Marks M.D., Gray J.C. The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in Arabidopsis, encodes a WD40 repeat protein. Plant Cell. 11:1999;1337-1349
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The TTG gene is required to specify epidermal cell fate and cell patterning in the Arabidopsis root
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Galway M.E., Masucci J.D., Lloyd A.M., Walbot V., Davis R.W., Schiefelbein J.W. The TTG gene is required to specify epidermal cell fate and cell patterning in the Arabidopsis root. Dev Biol. 166:1994;740-754
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TRIPTYCHON and CAPRICE mediate lateral inhibition during trichome and root hair patterning in Arabidopsis
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Schellmann S., Schnittger A., Kirik V., Wada T., Okada K., Beermann A., Thumfahrt J., Jurgens G., Hulskamp M. TRIPTYCHON and CAPRICE mediate lateral inhibition during trichome and root hair patterning in Arabidopsis. EMBO J. 21:2002;5036-5046
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The ENHANCER of TRY and CPC1 (ETC1) gene acts redundantly with TRIPTYCHON and CAPRICE in trichome and root hair cell patterning in Arabidopsis
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The authors show that the three related MYB-like proteins TRY, CPC and ETC1 act redundantly during trichome and root hair patterning. Although a redundancy of TRY and CPC had been shown previously, the try cpc double mutants still exhibit a regular spacing pattern, which raised doubt on whether the postulated models are correct. Therefore, a particularly important finding is that trichome patterning is almost completely abolished in the cpc try etc1 triple mutant.
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Kirik V., Simon M., Hulskamp M., Schiefelbein J. The ENHANCER OF TRY AND CPC1 (ETC1) gene acts redundantly with TRIPTYCHON and CAPRICE in trichome and root hair cell patterning in Arabidopsis. Dev Biol. 268:2004;506-513 The authors show that the three related MYB-like proteins TRY, CPC and ETC1 act redundantly during trichome and root hair patterning. Although a redundancy of TRY and CPC had been shown previously, the try cpc double mutants still exhibit a regular spacing pattern, which raised doubt on whether the postulated models are correct. Therefore, a particularly important finding is that trichome patterning is almost completely abolished in the cpc try etc1 triple mutant.
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A contradictory GLABRA3 allele helps define gene interactions controlling trichome development in Arabidopsis
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The newly discovered gl3-sst (glabra3-shape shifter) allele is here used to characterize the interactions between the known patterning genes. It is shown that a point mutation in a region relevant for the interactions with GL1 and TTG1 causes a reduced binding of these two proteins but not of TRY. In addition, it was shown that TRY competes with GL1 for binding to GL3.
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Esch J.J., Chen M., Sanders M., Hillestad M., Ndkium S., Idelkope B., Neizer J., Marks M.D. A contradictory GLABRA3 allele helps define gene interactions controlling trichome development in Arabidopsis. Development. 130:2003;5885-5894 The newly discovered gl3-sst (glabra3-shape shifter) allele is here used to characterize the interactions between the known patterning genes. It is shown that a point mutation in a region relevant for the interactions with GL1 and TTG1 causes a reduced binding of these two proteins but not of TRY. In addition, it was shown that TRY competes with GL1 for binding to GL3.
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Wada T., Kurata T., Tominaga R., Koshino-Kimura Y., Tachibana T., Goto K., Marks M.D., Shimura Y., Okada K. Role of a positive regulator of root hair development, CAPRICE, in Arabidopsis root epidermal cell differentiation. Development. 129:2002;5409-5419
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