FLT3: Receptor and ligand

Growth Factors

Volumn 22, Issue 2, 2004, Pages 71-73

  Drexler, Hans G ^a   Quentmeier, Hilmar ^a  

^a Dept of Human/Animal Cell Cultures ^*  (Germany)

Author keywords

AML; Cytokine; FLT3; FLT3L; Leukemia; Receptor

Indexed keywords

ADAPTOR PROTEIN; FLT3 LIGAND; GROWTH FACTOR; IMATINIB; MEMBRANE PROTEIN; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN TYROSINE KINASE;

ACUTE GRANULOCYTIC LEUKEMIA; AGE; BONE MARROW CELL; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CELL MATURATION; CELL PROLIFERATION; CELL STIMULATION; CELL SURVIVAL; CELL TYPE; CHRONIC MYELOID LEUKEMIA; DENDRITIC CELL; DRUG RESEARCH; DRUG TARGETING; GENE ACTIVATION; GENE MUTATION; GENETIC DISORDER; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; HUMAN; LEUKEMIA; LEUKEMOGENESIS; LYMPHOID CELL; MYELOID PROGENITOR CELL; NATURAL KILLER CELL; PATHOLOGY; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SHORT SURVEY; SIGNAL TRANSDUCTION; STEM CELL; STROMA CELL;

ANIMALS; FMS-LIKE TYROSINE KINASE 3; GROWTH SUBSTANCES; HUMANS; LEUKEMIA, MYELOCYTIC, ACUTE; MEMBRANE PROTEINS; MUTATION; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 3142714858     PISSN: 08977194     EISSN: None     Source Type: Journal    
DOI: 10.1080/08977190410001700989     Document Type: Short Survey

References (22)

1. Armstrong, S.A., Staunton, J.E., Silverman, L.B., Pieters, R., den Boer, M.L., Minden, M., et al. (2002) "MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia", Nature Genetics 30, 41-47.
2. 3 ligand by leukemic cells", Leukemia 10, 588-599.
3. 3 ligand on proliferation and survival of myeloid leukemia cells", Leukemia and Lymphoma 33, 83-91.
4. 3 in hematopoiesis and leukemia", Blood 100, 1532-1542.
5. Goldman, J.M. and Melo, J.V. (2003) "Chronic myeloid leukemia - Advances in biology and new approaches to treatment", New England Journal of Medicine 349, 1451-1464.
6. 2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs" , Nature 368, 643-648.
7. 3 in human hematologic malignancies", Leukemia and Lymphoma 43, 1541-1547.
8. Levis, M. and Small, D. (2003) "FLT3: It does matter in leukemia", Leukemia 77, 1738-1752.
9. 3 ligand: stem/progenitor cell factors with overlapping yet distinct activities", Blood 91, 1101-1134.
10. 3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells", Cell 75, 1157-1167.
11. 3 ligand: a growth factor for early hematopoietic progenitor cells", Blood 83, 2795-2801.
12. 3 ligand-treated mice: multiple dendritic cell subpopulations identified", Journal of Experimental Medicine 184, 1953-1962.
13. Matthews, W., Jordan, C.T., Wiegand, G.W., Pardoll, D. and Lemischka, I.R. (1991) "A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations", Cell 28, 1143-1152.
14. 3 gene found in acute myeloid leukemia", Leukemia 10, 1911-1918.
15. Piacibello, W., Sanavio, F., Garetto, L., Severino, A., Bergandi, D., Ferrario, J., et al. (1997) "Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood", Blood 89, 2644-2653.
16. 3 mutations in acute myeloid leukemia cell lines", Leukemia 17, 120-124.
17. Quentmeier, H., Dirks, W.G., MacLeod, R.A.F., Reinhardt, J., Zaborski, M. and Drexler, H.G. (2004) "Expression of HOX genes in acute leukemia cell lines with and without MLL translocations", Leukemia and Lymphoma 45, 567-574.
18. Rosnet, O., Mattei, M.G., Marchetto, S. and Birnbaum, D. (1991) "Isolation and chromosomal localization of a novel FMS-like tyrosine kinase gene", Genomics 9, 380-385.
19. 2 gene: cDNA cloning and expression in hematopoietic cells", Blood 82, 1110-1119.
20. 34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells", Proceedings of National Academy of Sciences of the USA 91, 459-463.
21. 3 in haematopoietic malignancies", Nature Reviews in Cancer 3, 650-665.
22. 3 ligand: role in control of hematopoietic and immune functions of the bone marrow", News in Physiological Sciences 18, 247-251.