Use of in vivo-generated biofilms from hemodialysis catheters to test the efficacy of a novel antimicrobial catheter lock for biofilm eradication in vitro

Journal of Clinical Microbiology

Volumn 42, Issue 7, 2004, Pages 3073-3076

  Kite, P ^a   Eastwood, K ^a   Sugden, S ^a   Percival, S L ^a,b  

^a LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

^b Global Development Centre   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EDETATE SODIUM;

ANTIMICROBIAL CATHETER LOCK; ARTERIOVENOUS FISTULA; ARTICLE; BACTERIAL COUNT; BACTERIUM CULTURE; BIOFILM; CATHETER; CATHETER INFECTION; DEVICE; DRUG EFFICACY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HEMODIALYSIS; IN VITRO STUDY; INSTRUMENT STERILIZATION; NONHUMAN; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; BIOFILMS; CATHETERS, INDWELLING; EDETIC ACID; HUMANS; RENAL DIALYSIS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA;

EID: 3142688240     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.42.7.3073-3076.2004     Document Type: Article

References (15)

1. Anaissie, E., G. Samonis, D. Kontoyiannis, J. Costerton, U. Sabharwal, G. Bodey, and I. Raad. 1995. Role of catheter colonization and infrequent hematogenous seeding in catheter-related infections. Eur. J. Clin. Microbiol. Infect. Dis. 14:135-137.
2. Carratala, J. J., Niubo, A. Fernandez-Sevilla, E. Juve, X. Castellsague, J. Berlanga, J. Linares, and F. Gudiol. 1999. Randomized, double-blind trial of an antibiotic-lock technique for prevention of gram-positive central venous catheter-related infection in neutropenic patients with cancer. Antimicrob. Agents Chemother. 43:2200-2204.
3. Christensen, G. D., L. Baldassari, and W. A. Simpson. 1994. Colonization of medical devices by coagulase-negative staphylococci, p. 45-78. In A. L. Bisno and F. A. Waldvogel (ed.), Infections associated with indwelling medical devices, 2nd ed. American Society for Microbiology, Washington, D.C.
4. Evans, R. C., and C. J. Holmes. 1987. Effect of vancomycin hydrochloride on Staphylococcus epidermidis biofilm associated with silicone elastomer. Antimicrob. Agents Chemother. 31:889-894.
5. Garland, J. S., K. Henrickson, and D. G. Maki. 2002. The 2002 Hospital Infection Control Practices Advisory Committee, Centers for Disease Control and Prevention, guideline for prevention of intravascular device-related infection. Pediatrics 110:1009-1013.
6. Gil, M. L., M. Casanova, and J. P. Martinez. 1994. Changes in the cell wall glycoprotein composition of Candida albicans associated to the inhibition of germ tube formation by EDTA. Arch. Microbiol. 161:489-494.
7. Haley, R., D. H. Culver, J. W. White W. M. Morgan, and T. G. Emori. 1985. The nationwide nosocomial infection rate: a new need for vital statistics. Am. J. Epidemiol. 121:159-167.
8. Henrickson, K. J., R. A. Axtell, S. M. Hoover, S. M. Kuhn, J. K. Pritchett, S. C. Klein, and P. John. 2000. Prevention of central venous catheter-related infections and the thrombotic events in immunocompromised children by the use of vancomycin/ciprofloxacin/heparin flush solution: a randomized, multicenter, double-blind trial. J. Clin. Oncol. 18:1269-1278.
9. Mermel, L. A. 2000. Prevention of intravascular catheter-related infections. Ann. Intern. Med. 132:391-402.
10. Raad, I., R. Hachem, R. K. Tcholakian, and R. Sheretz. 2002. Efficacy of minocycline and EDTA lock solution in preventing catheter-related bacteremia, septic phlebitis, and endocarditis in rabbits. Antimicrob. Agents Chemother. 46:327-332.
11. Raad, I., and R. Sherertz. November 1994. M-EDTA pharmaceutical preparations and uses thereof. U.S. patent 5, 362, 754.
12. Reardon, D. M., B. Warner, B., and E. A. Trowbridge. 1991. EDTA, the traditional anticoagulant of haematology: with increased automation is it time for review? Med. Lab. Sci. 48:72-75.
13. Root, J. L., O. R. McIntyre, N. J. Jacobs, and C. P. Daghlian. 1988. Inhibitory effect of disodium EDTA upon the growth of Staphylococcus epidermidis in vitro: relation to infection prophylaxis of Hickman catheters. Antimicrob. Agents Chemother. 32:1627-1631.
14. Rose, R. K. 2000. The role of calcium in oral streptococcal aggregation and the implications for biofilm formation and retention. Biochim. Biophys. Acta 1475:76-82.
15. Schwartz, C., K. J. Henrickson, K. Roghmann, and K. Powell. 1990. Prevention of bacteremia attributed to luminal colonization of tunneled central venous catheters with vancomycin-susceptible organisms. J. Clin. Oncol. 8: 1591-1597.