Pharmacogenomics: From genes to drug sensitivity;La pharmacogénétique: Le lien entre génes et réponse aux médicaments

Medecine/Sciences

Volumn 20, Issue 6-7, 2004, Pages 634-636

  Loriot, Marie Anne ^a   Beaune, Philippe ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL GENETICS; DRUG SENSITIVITY; GENE; GENETIC POLYMORPHISM; GENOTYPE; MOLECULAR GENETICS; NOTE; PHARMACOGENOMICS; PHENOTYPE; TREATMENT OUTCOME;

EID: 3142684123     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/2004206-7634     Document Type: Note

References (10)

1. Rapport de l'Agence française de sécurité sanitaire des produits de santé. Paris: AFSSAPS, 2001.
2. Evans WE, Relling MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 1999; 286: 487-91.
3. Oscarson M. Pharmacogenetics of drug metabolising enzymes: importance for personalised medecine. Clin Chem Lab Med 2003; 41: 573-80.
4. Zanger UM, Raimundo S, Eichelbaum M. Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry. Naunyn-Schmiedeberg's Arch Pharmacol 2004; 369: 23-37.
5. Kirchheiner J, Brosen K, Dahl ML, et al. CYP2D6 and CYP2C19 genotype-based dose recommendations for anti-depressants: a first step towards subpopulation-specific dosages. Acta Psychiatr Scand 2001; 104: 173-92.
6. Relling MV, Hancock ML, River S, et al. Mercaptopurine therapy intolerance and heterozygoty at the thiopurine S-methyl-transferase gene locus. J Natl Cancer Inst 1999; 91: 2001-8.
7. Ando Y, Saka H, Ando M, et al. Polymorphisms of UDP-glucuronosyl- transferase gene and irinotecan toxicity: a pharmacogenetics analysis. Cancer Res 2000; 60: 6921-6.
8. Daly AK, King BP. Pharmacogenetics of oral anticoagulants. Pharmacogenetics 2003; 13: 247-52.
9. Anglicheau D, Verstuyft C, Laurent-Puig P, et al. Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients. J Am Soc Nephrol 2003; 14: 1889-96.
10. Swiss HIV Cohort Study. Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study. Lancet 2002; 359: 30-6.