메뉴 건너뛰기




Volumn 42, Issue 6, 2004, Pages 317-322

The identification of three human metabolites of a peptide-doxorubicin conjugate using HPLC-MS-MS in positive and negative ionization modes

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; DOXORUBICIN DERIVATIVE; DRUG METABOLITE; LEUCINE DOXORUBICIN; PEPTIDE DOXORUBICIN CONJUGATE; UNCLASSIFIED DRUG;

EID: 3142681640     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chromsci/42.6.317     Document Type: Article
Times cited : (16)

References (8)
  • 3
    • 0037111113 scopus 로고    scopus 로고
    • Determination of a peptide-doxorubicin, prostate specific antigen activated prodrug, and its active metabolites in human plasma using high-performance liquid chromatography with fluorescence detection; stabilization of the peptide prodrug with EDTA
    • M.S. Schwartz and B.K. Matuszewski. Determination of a peptide-doxorubicin, prostate specific antigen activated prodrug, and its active metabolites in human plasma using high-performance liquid chromatography with fluorescence detection; stabilization of the peptide prodrug with EDTA. J. Chromatogr. B 780(1): 171-82 (2002).
    • (2002) J. Chromatogr. B , vol.780 , Issue.1 , pp. 171-182
    • Schwartz, M.S.1    Matuszewski, B.K.2
  • 4
    • 0018841542 scopus 로고
    • Binding specificity of chemically and enzymatically activated anthracycline anticancer agents to nucleic acids
    • B. Sinha. Binding specificity of chemically and enzymatically activated anthracycline anticancer agents to nucleic acids. Chem.-Biol. Interactions 30: 67-77 (1980).
    • (1980) Chem.-Biol. Interactions , vol.30 , pp. 67-77
    • Sinha, B.1
  • 5
    • 0026500568 scopus 로고
    • Fully automated determination of a new anthracycline N-I- leucyldoxorubicin and six metabolites in plasma by high-performance liquid chromatography with on-line sample handling
    • J. de Jong, C. Munniksma, W. Guerand, A. Bast, and W. Van der Vijgh. Fully automated determination of a new anthracycline N-I-leucyldoxorubicin and six metabolites in plasma by high-performance liquid chromatography with on-line sample handling. J. Chromatogr. 574: 273-81 (1992).
    • (1992) J. Chromatogr. , vol.574 , pp. 273-281
    • De Jong, J.1    Munniksma, C.2    Guerand, W.3    Bast, A.4    Van Der Vijgh, W.5
  • 6
    • 0027052703 scopus 로고
    • Plasma pharmacodynamics of a new prodrug N-I-leucyldoxorubicin and its metabolites in a phase I clinical trial
    • J. de Jong, G. Geijssen, C. Munniksma, J. Vermorken, and W. van der Vijgh. Plasma pharmacodynamics of a new prodrug N-I-leucyldoxorubicin and its metabolites in a phase I clinical trial. J. Clin. Oncol. 10(12): 1897-1906 (1992).
    • (1992) J. Clin. Oncol. , vol.10 , Issue.12 , pp. 1897-1906
    • De Jong, J.1    Geijssen, G.2    Munniksma, C.3    Vermorken, J.4    Van Der Vijgh, W.5
  • 7
    • 0342546480 scopus 로고    scopus 로고
    • Simultaneous determination of four anthracyclines and three metabolites in human serum by liquid chromatography-electrospray mass spectrometry
    • F. Lachatre, P. Marquet, S. Ragot, J. Gaulier, P. Cardot, and J. Dupuy. Simultaneous determination of four anthracyclines and three metabolites in human serum by liquid chromatography-electrospray mass spectrometry. J. Chromatogr. B 738: 281-91 (2000).
    • (2000) J. Chromatogr. B , vol.738 , pp. 281-291
    • Lachatre, F.1    Marquet, P.2    Ragot, S.3    Gaulier, J.4    Cardot, P.5    Dupuy, J.6
  • 8
    • 0344958268 scopus 로고
    • Daunorubicin aldo-keto reductases: Enantioface differential reduction of the side chain carbonyl group of antitumor anthracyclines
    • S. Penco, G. Cassinelli, A. Vigevani, P. Zini, G. Rivola, and F. Arcamone. Daunorubicin aldo-keto reductases: Enantioface differential reduction of the side chain carbonyl group of antitumor anthracyclines. Gazzetta Chimica Italiana 115: 195-97 (1985).
    • (1985) Gazzetta Chimica Italiana , vol.115 , pp. 195-197
    • Penco, S.1    Cassinelli, G.2    Vigevani, A.3    Zini, P.4    Rivola, G.5    Arcamone, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.