-
1
-
-
0345535621
-
Development of difluoromethylornithine (DFMO) as a chemoprevention agent
-
Meyskens FL Jr, Gerner EW. Development of difluoromethylornithine (DFMO) as a chemoprevention agent. Clin Cancer Res 1999;5:945-51.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 945-951
-
-
Meyskens Jr., F.L.1
Gerner, E.W.2
-
2
-
-
0021343859
-
Phase I trial and pharmacokinetic studies of α- difluoromethylornithine - An inhibitor of polyamine biosynthesis
-
Abeloff MD, Slavik M, Luk GD, et al. Phase I trial and pharmacokinetic studies of α-difluoromethylornithine-an inhibitor of polyamine biosynthesis. J Clin Oncol 1984;2:124-30.
-
(1984)
J Clin Oncol
, vol.2
, pp. 124-130
-
-
Abeloff, M.D.1
Slavik, M.2
Luk, G.D.3
-
3
-
-
0023690550
-
A phase I trial of recombinant interferon-α and α-difluoromethylornithine in metastatic melanoma
-
Croghan MK, Booth A, Meyskens FL Jr. A phase I trial of recombinant interferon-α and α-difluoromethylornithine in metastatic melanoma. J Biol Response Modif 1988;7:409-15.
-
(1988)
J Biol Response Modif
, vol.7
, pp. 409-415
-
-
Croghan, M.K.1
Booth, A.2
Meyskens Jr., F.L.3
-
4
-
-
0022999939
-
A phase II study of α-difluoromethylornithine (DFMO) for the treatment of metastatic melanoma
-
Meyskens FL, Kingsley EM, Glattke T, Loescher L, Booth A. A phase II study of α-difluoromethylornithine (DFMO) for the treatment of metastatic melanoma. Invest New Drugs 1986;4:257-62.
-
(1986)
Invest New Drugs
, vol.4
, pp. 257-262
-
-
Meyskens, F.L.1
Kingsley, E.M.2
Glattke, T.3
Loescher, L.4
Booth, A.5
-
5
-
-
0022499206
-
Phase II trials of α-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer
-
Abeloff MD, Rosen ST, Luk GD, Baylin SB, Zeltzman M, Sjoerdsma A. Phase II trials of α-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer. Cancer Treat Rep 1986;70:843-5.
-
(1986)
Cancer Treat Rep
, vol.70
, pp. 843-845
-
-
Abeloff, M.D.1
Rosen, S.T.2
Luk, G.D.3
Baylin, S.B.4
Zeltzman, M.5
Sjoerdsma, A.6
-
6
-
-
0025311468
-
Evaluation of continuous-infusion α-difluoromethylornithine therapy for colorectal carcinoma
-
Ajani JA, Ota DM, Grossie VB Jr, et al. Evaluation of continuous-infusion α-difluoromethylornithine therapy for colorectal carcinoma. Cancer Chemother Pharmacol 1990;26:223-6.
-
(1990)
Cancer Chemother Pharmacol
, vol.26
, pp. 223-226
-
-
Ajani, J.A.1
Ota, D.M.2
Grossie Jr., V.B.3
-
8
-
-
0031454230
-
α-Difluoromethylornithine ototoxicity. Chemoprevention clinical trial results
-
Pasic TR, Heisey D, Love RR. α-Difluoromethylornithine ototoxicity. Chemoprevention clinical trial results. Arch Otolaryngol Head Neck Surg 1997;123:1281-6.
-
(1997)
Arch Otolaryngol Head Neck Surg
, vol.123
, pp. 1281-1286
-
-
Pasic, T.R.1
Heisey, D.2
Love, R.R.3
-
9
-
-
0027601440
-
Evaluation of α-difluoromethylornithine as a potential chemopreventive agent: Tolerance to daily oral administration in humans
-
Creaven PJ, Pendyala L, Petrelli NJ. Evaluation of α- difluoromethylornithine as a potential chemopreventive agent: tolerance to daily oral administration in humans. Cancer Epidemiol, Biomarkers & Prev 1993;2:243-7.
-
(1993)
Cancer Epidemiol, Biomarkers & Prev
, vol.2
, pp. 243-247
-
-
Creaven, P.J.1
Pendyala, L.2
Petrelli, N.J.3
-
10
-
-
0029920326
-
Toxicity evaluation of difluoromethylornithine: Doses for chemoprevention trials
-
Loprinzi CL, Messing EM, O'Fallon JR, et al. Toxicity evaluation of difluoromethylornithine: doses for chemoprevention trials. Cancer Epidemiol, Biomarkers & Prev 1996;5:371-4.
-
(1996)
Cancer Epidemiol, Biomarkers & Prev
, vol.5
, pp. 371-374
-
-
Loprinzi, C.L.1
Messing, E.M.2
O'Fallon, J.R.3
-
11
-
-
0027983571
-
Dose de-escalation chemoprevention trial of α- difluoromethylornithine in patients with colon polyps
-
Meyskens FL Jr, Emerson SS, Pelot D, et al. Dose de-escalation chemoprevention trial of α-difluoromethylornithine in patients with colon polyps. J Natl Cancer Inst 1994;86:1122-30.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1122-1130
-
-
Meyskens Jr., F.L.1
Emerson, S.S.2
Pelot, D.3
-
12
-
-
0027266833
-
Randomized phase I chemoprevention dose-seeking study of α-difluoromethylornithine
-
Love RR, Carbone PP, Verma AK, et al. Randomized phase I chemoprevention dose-seeking study of α-difluoromethylornithine. J Natl Cancer Inst 1993;85:732-37.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 732-737
-
-
Love, R.R.1
Carbone, P.P.2
Verma, A.K.3
-
13
-
-
0031661696
-
Phase I chemoprevention study of piroxicam and α- difluoromethylornithine
-
Carbone PP, Douglas JA, Larson PO, et al. Phase I chemoprevention study of piroxicam and α-difluoromethylornithine. Cancer Epidemiol, Biomarkers & Prev 1998;7:907-12.
-
(1998)
Cancer Epidemiol, Biomarkers & Prev
, vol.7
, pp. 907-912
-
-
Carbone, P.P.1
Douglas, J.A.2
Larson, P.O.3
-
14
-
-
0031889260
-
Phase I dose deescalation trial of α-difluoromethylornithine in patients with grade 3 cervical intraepithelial neoplasia
-
Mitchell MF, Tortolero-Luna G, Lee JJ, et al. Phase I dose deescalation trial of α-difluoromethylornithine in patients with grade 3 cervical intraepithelial neoplasia. Clin Cancer Res 1998;4:303-10.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 303-310
-
-
Mitchell, M.F.1
Tortolero-Luna, G.2
Lee, J.J.3
-
15
-
-
0026618065
-
Polyamine contents in rectal and buccal mucosae in humans treated with oral difluoromethylornithine
-
Boyle JO, Meyskens FL Jr, Garewal HS, Gerner EW. Polyamine contents in rectal and buccal mucosae in humans treated with oral difluoromethylornithine. Cancer Epidemiol, Biomarkers & Prev 1992; 1:131-5.
-
(1992)
Cancer Epidemiol, Biomarkers & Prev
, vol.1
, pp. 131-135
-
-
Boyle, J.O.1
Meyskens Jr., F.L.2
Garewal, H.S.3
Gerner, E.W.4
-
16
-
-
0031733846
-
A randomized, placebocontrolled trial of low-dose α- difluoromethylornithine in individuals at risk for colorectal cancer
-
Love RR, Jacoby R, Newton MA, et al. A randomized, placebocontrolled trial of low-dose α-difluoromethylornithine in individuals at risk for colorectal cancer. Cancer Epidemiol, Biomarkers & Prev 1998;7:989-92.
-
(1998)
Cancer Epidemiol, Biomarkers & Prev
, vol.7
, pp. 989-992
-
-
Love, R.R.1
Jacoby, R.2
Newton, M.A.3
-
17
-
-
0042098091
-
Effect of α-difluoromethylornithine on rectal mucosal levels of polyamines in a randomized, double-blinded trial for colon cancer prevention
-
Meyskens FL Jr, Gerner EW, Emerson S, et al. Effect of α-difluoromethylornithine on rectal mucosal levels of polyamines in a randomized, double-blinded trial for colon cancer prevention. J Natl Cancer Inst 1998;90:1212-8.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1212-1218
-
-
Meyskens Jr., F.L.1
Gerner, E.W.2
Emerson, S.3
-
18
-
-
0035036630
-
Effects of difluoromethylornithine chemoprevention on audiometry thresholds and otoacoustic emissions
-
Doyle KJ, McLaren CE, Shanks JE, Galus CM, Meyskens FL. Effects of difluoromethylornithine chemoprevention on audiometry thresholds and otoacoustic emissions. Arch Otolaryngol Head Neck Surg 2001;127:553-8.
-
(2001)
Arch Otolaryngol Head Neck Surg
, vol.127
, pp. 553-558
-
-
Doyle, K.J.1
McLaren, C.E.2
Shanks, J.E.3
Galus, C.M.4
Meyskens, F.L.5
-
19
-
-
0035869019
-
Recommendations for cancer prevention trials using potentially ototoxic test agents
-
Shotland LI, Ondrey FG, Mayo KA, Viner JL. Recommendations for cancer prevention trials using potentially ototoxic test agents. J Clin Oncol 2001;19:1658-63.
-
(2001)
J Clin Oncol
, vol.19
, pp. 1658-1663
-
-
Shotland, L.I.1
Ondrey, F.G.2
Mayo, K.A.3
Viner, J.L.4
-
20
-
-
0025363392
-
Cochlear damage and increased threshold in α- difluoromethylornithine (DFMO) treated guinea pigs
-
Salzer SJ, Mattox DE, Brownell WE. Cochlear damage and increased threshold in α-difluoromethylornithine (DFMO) treated guinea pigs. Hear Res 1990;46:101-12.
-
(1990)
Hear Res
, vol.46
, pp. 101-112
-
-
Salzer, S.J.1
Mattox, D.E.2
Brownell, W.E.3
-
21
-
-
0022639864
-
Identification of polyamines in the cochlea of the rat and their potential role in hearing
-
Schweitzer L, Casseday JH, Sjoerdsma A, McCann PP, Bartolome JV. Identification of polyamines in the cochlea of the rat and their potential role in hearing. Brain Res Bull 1986;16:215-8.
-
(1986)
Brain Res Bull
, vol.16
, pp. 215-218
-
-
Schweitzer, L.1
Casseday, J.H.2
Sjoerdsma, A.3
McCann, P.P.4
Bartolome, J.V.5
-
23
-
-
0028097041
-
Spermine and spermidine as gating molecules for inward rectifier K+ channels
-
Ficker E, Taglialatela M, Wible BA, Henley CM, Brown AM. Spermine and spermidine as gating molecules for inward rectifier K+ channels. Science 1994;266:1068-72.
-
(1994)
Science
, vol.266
, pp. 1068-1072
-
-
Ficker, E.1
Taglialatela, M.2
Wible, B.A.3
Henley, C.M.4
Brown, A.M.5
-
24
-
-
0033288042
-
Auditory deprivation of the central auditory system resulting from selective inner hair cell loss: Animal model of auditory neuropathy
-
Salvi RJ, Wang J, Ding D, Stecker N, Arnold S. Auditory deprivation of the central auditory system resulting from selective inner hair cell loss: animal model of auditory neuropathy. Scand Audiol Suppl 1999;51:1-12.
-
(1999)
Scand Audiol Suppl
, vol.51
, pp. 1-12
-
-
Salvi, R.J.1
Wang, J.2
Ding, D.3
Stecker, N.4
Arnold, S.5
-
25
-
-
0033949479
-
Characterization of the ototoxicity of difluoromethylornithine and its enantiomers
-
McWilliams ML, Chen GD, Fechter LD. Characterization of the ototoxicity of difluoromethylornithine and its enantiomers. Toxicol Sci 2000;56:124-32.
-
(2000)
Toxicol Sci
, vol.56
, pp. 124-132
-
-
McWilliams, M.L.1
Chen, G.D.2
Fechter, L.D.3
-
26
-
-
0027383434
-
Ototoxicity of chemotherapeutic agents
-
Schweitzer VG. Ototoxicity of chemotherapeutic agents. Otolaryngol Clin North Am 1993;26:759-89.
-
(1993)
Otolaryngol Clin North Am
, vol.26
, pp. 759-789
-
-
Schweitzer, V.G.1
-
27
-
-
0015013715
-
Primary structural changes in the organ of Corti after acoustic overstimulation
-
Spoendlin H. Primary structural changes in the organ of Corti after acoustic overstimulation. Acta Otolaryngol 1971;71:166-76.
-
(1971)
Acta Otolaryngol
, vol.71
, pp. 166-176
-
-
Spoendlin, H.1
-
28
-
-
0025614370
-
Interaction of cisplatin and noise on the peripheral auditory system
-
Gratton MA, Salvi RJ, Kamen BA, Saunders SS. Interaction of cisplatin and noise on the peripheral auditory system. Hear Res 1990;50:211-23.
-
(1990)
Hear Res
, vol.50
, pp. 211-223
-
-
Gratton, M.A.1
Salvi, R.J.2
Kamen, B.A.3
Saunders, S.S.4
|