Choroid plexus cysts in the mid-trimester fetus - Practical application suggests superiority of an individualized risk method of counseling for trisomy 18

Prenatal Diagnosis

Volumn 22, Issue 9, 2002, Pages 792-797

  Bird, L M ^a,b,c   Dixson, B ^a   Masser Frye, D ^a   Mestre, L ^a   Ribas, L ^a   Mullen, L ^d   Kalla, K ^e   Carder, K ^a   Huslig, M ^a   Catanzarite, V A ^a   Jones, M C ^a,b,c  

^a Sharp and Children's Prenatal Diagnostic Center   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c RADY CHILDREN'S HOSPITAL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Genetic Services   (United States)

Author keywords

Choroid plexus cyst; Risk assessment; Trisomy 18

Indexed keywords

ADULT; ANEUPLOIDY; ARTICLE; CHOROID PLEXUS; CHOROID PLEXUS CYST; CHOROID PLEXUS TUMOR; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; FEMALE; HEALTH CARE COST; HUMAN; MAJOR CLINICAL STUDY; PATIENT COUNSELING; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; RISK ASSESSMENT; SECOND TRIMESTER PREGNANCY; SENSITIVITY AND SPECIFICITY; TRISOMY 18;

ADULT; BRAIN DISEASES; CHOROID PLEXUS; CHROMOSOMES, HUMAN, PAIR 18; CYSTS; DIRECTIVE COUNSELING; FEMALE; FETAL DISEASES; GENETIC COUNSELING; HUMANS; PREGNANCY; PREGNANCY TRIMESTER, SECOND; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TRISOMY; ULTRASONOGRAPHY, PRENATAL;

EID: 3142670985     PISSN: 01973851     EISSN: None     Source Type: Journal    
DOI: 10.1002/pd.411     Document Type: Article

References (47)

1. Achiron R, Barkai G, Katznelson MB, Nashiach S. 1991. Fetal lateral ventricle choroid plexus cysts: the dilemma of amniocentesis. Obstet Gynecol 78: 815-818.
2. Bakos O, Moen KS, Hansson S. 1998. Prenatal karyotyping of choroid plexus cysts. Eur J Ultrasound 8: 79-83.
3. Benacerraf BR, Laboda LA. 1989. Cyst of the fetal choroid plexus: a normal variant? Am J Obstet Gynecol 160: 319-321.
4. Brown T, Kliewer MA, Hertzberg BS, et al. 1999, A role for maternal serum screening in detecting chromosomal abnormalities in fetuses with isolated choroid plexus cysts: a prospective multicentre study. Prenat Diagn 19: 405-410.
5. Chan L, Hixson JL, Laifer SA, Marchese SG, Martin JG, Hill LM. 1989. A sonographic and karyotypic study of second-trimester fetal choroid plexus cysts. Obstet Gynecol 73: 703-706.
6. Chinn DH, Miller EI, Worthy LM, Towers CV. 1991. Sonographically detected fetal choroid plexus cysts. J Ultrasound Med 10: 255-258.
7. Chitty LS, Chudleigh T. 1993. Choroid plexus cysts - when to karyotype? BMUS Bulletin Feb: 40-41.
8. Choong S, Meagher S. 1999. Management of choroid plexus cysts in the mid-trimester fetus. Aust NZ J Obstet Gynecol 39: 7-11.
9. Clark SL, Devore GR, Sabey PL. 1988. Prenatal diagnosis of cysts of the fetal choroid plexus. Obstet Gynecol 72: 585-587.
10. Donnenfeld AE. 1995. Prenatal sonographic detection of isolated fetal choroid plexus cysts: should we screen for trisomy 18? J Med Screen 2: 18-21.
11. Donnenfeld AE. 1997. Risk and benefit analysis of offering karyotyping for an isolated choroid plexus cyst. Ultrasound Obstet Gynecol 9: 67-68.
12. Gabrielli S, Reece EA, Pilu G, et al. 1989. The clinical significance of prenatally diagnosed choroid plexus cysts. Am J Obstet Gynecol 160: 1207-1210.
13. Geary M, Patel S, Lamont R. 1997. Isolated choroid plexus cysts and association with fetal aneuploidy in an unselected population. Ultrasound Obstet Gynecol 10: 171-173.
14. Ghidini A, Strobelt N, Locatelli A, Mariani E, Piccoli MG, Vergani P. 2000. Isolated fetal choroid plexus cysts: role of ultrasongraphy in establishment of the risk of trisomy 18. Am J Obstet Gynecol 182:972-977.
15. Gratton RJ, Hogge WA, Aston CE. 1996. Choroid plexus cysts and trisomy 18: risk modification on maternal age and multiple-marker screening. Am J Obstet Gynecol 175: 1493-1497.
16. Gray DL, Winborn RC, Suessen TL, Crane JP. 1996. Is genetic amniocentesis warranted when isolated choroid plexus cysts are found? Prenat Diagn 16: 983-990.
17. Gross SJ, Shulman LP, Tolley EA, et al. 1995. Isolated fetal choroid plexus cysts and trisomy 18: a review and meta-analysis. Am J Obstet Gynecol 172: 83-87.
18. Gupta JKI, Cave M, Lilford RJ, et al. 1995. Clinical significance of fetal choroid plexus cysts. Lancet 346: 724-729.
19. Gupta JK, Khan KS, Thornton JG, Lilford RJ. 1997. Management of fetal choroid plexus cysts. Br J Obstet Gynaecol 104: 881-886.
20. Gupta JK, Khan KS, Lilford RJ. 1998. Management of fetal choroid plexus cysts (reply to letter). Br J Obstet Gynaecol 105: 245-246.
21. Howard RJ, Tuck SM, Long J, Thomas VA. 1992. The significance of choroid plexus cysts in fetuses at 18-20 weeks. An indication for amniocentesis? Prenat Diagn 12: 685-688.
22. Jou H, Shyu M, Lee C, et al. 1997. Fetuses with choroid plexus cysts are at high risk for Down syndrome. J Maternal Fetal Invest 7: 12-15.
23. Kennedy KA, Carey JC. 1993. Choroid plexus cysts: significance and current management practices. Seminars Ultrasound, CT, MRI 14: 23-30.
24. Kupferminc MJ, Tamura RK, Sabbagha RE, Parilla BV, Cohen LS, Pergament E. 1994. Isolated choroid plexus cysts(s): an indication for amniocentesis. Am J Obstet Gynecol 171: 1068-1071.
25. Leonardi MR, Wolfe HM, Lanouette JM, Landwehr JB, Johnson MP, Evans MI. 1998. The apparently isolated choroid plexus cyst: importance of minor abnormalities in predicting the risk for aneuploidy. Fetal Diag Ther 13: 49-52.
26. Morcos CL, Platt LD, Carlson DE, Gregory KD, Greene NH, Korst LM. 1998. The isolated choroid plexus cyst. Obstet Gynecol 92:232-236.
27. Nadel AS, Bromley BS, Frigoletto FD, Estroff JA, Benacerraf BR. 1992. Isolated choroid plexus cysts in the second-trimester fetus: is amniocentesis really indicated? Radiology 185: 545-548.
28. Nava S, Godmilow L, Reeser S, Ludomirsky A, Donnenfeld. 1994. Significance of sonographically detected second-trimester choroid plexus cysts: a series of 211 cases and a review of the literature. Ultrasound Obstet Gynecol 4: 448-451.
29. Nicolaides KH, Rodeck CH, Gosden CM. 1986. Rapid karyotyping in non-lethal fetal malformations. Lancet 1: 283-286.
30. Oettinger M, Odeh M, Korenblum R, Markovits J. 1993. Antenatal diagnosis of choroid plexus cyst: suggested management. Obstet Gynecol Survey 48: 635-639.
31. Ostlere SJ, Irving HC, Lilford RJ. 1990. Fetal choroid plexus cysts: a report of 100 cases. Radiology 175: 753-755.
32. Peleg D, Yankowitz J. 1998. Choroid plexus cysts and aneuploidy. J Med Genet 35: 554-557.
33. Perpignano MC, Cohen HL, Klein VR, et al. 1992. Fetal choroid plexus cysts: beware the smaller cyst. Radiology 182: 715-717.
34. Platt LD, Carlson DR, Medearis AL, Wall CA. 1991. Fetal choroid plexus cysts in the second trimester of pregnancy: a cause for concern. Am J Obstet Gynecol 164: 1652-1656.
35. Porto M, Murata Y, Warneke LA, Keegan KA. 1993. Fetal choroid plexus cysts: an independent risk factor for chromosomal anomalies. J Clin Ultrasound 21: 103-108.
36. Reinsch RC. 1997. Choroid plexus cysts - association with trisomy: prospective review of 16059 patients. Am J Obstet Gynecol 176: 1381-1383.
37. Ricketts NE, Lowe EM, Patel NB. 1987. Prenatal diagnosis of choroid plexus cysts. Lancet 1: 213-214.
38. Shields LE, Uhrich SB, Easterling TR, Cyr DR, Mack LA. 1996. Isolated fetal choroid plexus cysts and karyotype analysis: is it necessary? J Ultrasound Med 15: 389-394.
39. Snijders RJ, Shawa L, Nicolaides KH. 1994. Fetal choroid plexus cysts and trisomy 18: assessment of risk based on ultrasound findings and maternal age. Prenat Diagn 14: 1119-1127.
40. Sohn C, Gast A-S, Krapfl E. 1997. Isolated fetal choroid plexus cysts: not an indication for genetic diagnosis? Fetal Diag Ther 12: 255-259.
41. Sullivan A, Giudice T, Vavelidis F, Thiagarajah S. 1999. Choroid plexus cysts: is biochemical testing a valuable adjunct to targeted ultrasonography? Am J Obstet Gynecol 181: 260-265.
42. Thorpe-Beeston JG, Gosden M, Nicolaides KH. 1990. Choroid plexus cysts and chromosomal defects. Br J Radiol 63: 783-786.
43. Vintzileos AM, Ananth CV, Fisher AJ, et al. 1998. An economic evaluation of prenatal strategies for detection of trisomy 18. Am J Obstet Gynecol 179: 1220-1224.
44. Walkinshaw S, Pilling D, Spriggs A. 1994. Isolated choroid plexus cysts - the need for routine offer of karyotyping. Prenat Diagn 14: 663-667.
45. Walkinshaw SA. 2000. Fetal choroid plexus cysts: are we there yet? Prenat Diagn 20: 657-662.
46. Yoder PR, Sabbagha RE, Gross SJ, Zelop CM. 1999. The secondtrimester fetus with isolated choroid plexus cysts: a meta-analysis of risk of trisomies 18 and 21. Am J Obstet Gynecol 93: 869-872.
47. Zerres K, Schuler H, Gembruch U, Bald R, Hansmann M, Schwanitz G. 1992. Chromosomal findings in fetuses with prenatally diagnosed cysts of the choroid plexus. Hum Genet 89: 301-304.