Fetuses with choroid plexus cysts are at high risk for Down syndrome

Journal of Maternal-Fetal Investigation

Volumn 7, Issue 1, 1997, Pages 12-15

  Jou, Hei Jen ^a   Shyu, Ming Kwang ^b   Lee, Chien Nan ^c   Shih, Jin Chung ^c   Guo, Yih Shing ^d   Huang, Bih Fen ^a   Huang, Chun Liang ^c   Hsieh, Fon Jou ^d  

^a Department of Obstetrics and Gynecology ^*  (Taiwan)

^b TAIWAN ADVENTIST HOSPITAL   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^d NATIONAL TAIPEI UNIVERSITY OF NURSING AND HEALTH SCIENCES   (Taiwan)

Author keywords

Choroid plexus cyst; Down syndrome; Trisomy 18

Indexed keywords

ADULT; AMNIOCENTESIS; ANEUPLOIDY; ARTICLE; BRAIN CYST; CHOROID PLEXUS; CHROMOSOME MOSAICISM; DOWN SYNDROME; FEMALE; FETUS; FETUS ECHOGRAPHY; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SECOND TRIMESTER PREGNANCY; TAIWAN; TRISOMY 18; TRISOMY 21;

EID: 0030932822     PISSN: 09396322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Lin SJ. Down syndrome. Acta Paediatr Sin 1994;35A:28-31.
2. Mooney RA, Peterson CJ, French ÇA, et al. Effectiveness of combining maternal serum alpha-fetoprotein and hCG in a second-trimester screening program for Down syndrome. Obstet Gynecol 1994;84:298-303.
3. Chinn DH, Miller El, Worthy LM, et al. Sonographically detected fetal choroid plexus cysts: frequency and association with aneuploidy. J Ultrasound Med 1991;10:255-8.
4. Twinning P, Zuccollo J, Clewes J, et al. Fetal choroid plexus cysts: a prospective study and review of the literature. Br J Radiol 1990;64: 98-102.
5. Kupfermine MJ, Tamura RK, Sabbagha RE, et al. Isolated choroid plexus cyst(s): an indication for amniocentesis. Am J Obstet Gynecol 1994;171:1068-71.
6. Chudleigh P, Pearce JM, Campbell S. The prenatal diagnosis of transient cysts of the fetal choroid plexus. Prenat Diagn 1984;4:135-7.
7. Clark SL, DeVore GR, Sabey PL. Prenatal diagnosis of cysts of the fetal choroid plexus. Obstet Gynecol 1988;72:585-6.
8. Platt LD, Carlson DE, Medearis AL, et al. Fetal choroid plexus cysts in the second trimester of pregnancy: a cause for concern. Am J Obstet Gynecol 1991;164:1652-6.
9. Gross Si, Shulman LP, Tolley EA, et al. Isolated choroid plexus cysts and trisomy 18: a review and meta-analysis. Am J Obstet Gynecol 1995;172:83-7.
10. Chitkara U, Cogswell C, Norton K, et al. Choroid plexus cysts in the fetus: a benign anatomic variant or pathologic entity? Report of 41 cases and review of the literature. Obstet Gynecol 1988;72:185-9.
11. Ostlere SJ, Irving HC, Lilford RJ. Fetal choroid plexus cysts: a report of 100 cases. Radiology 1990; 175:753-5.
12. Nadel AS, Bromley BS, Frigoletto FD, et al. Isolated choroid plexus cysts in the second-trimester fetus: is amniocentesis really indicated? Radiology 1992;185:545-8.
13. Nyberg DA, Kramer D, Resta RG, et al. Prenatal sonographic findings of trisomy 18: review of 47 cases. J Ultrasound Med 1993;2:103-13.
14. Hsieh FJ, Jou JH, Ko TM, et al. Sonography of the fetuses with chromosomal aberrations. Adv Obstet Perinatol 1991;2:29-35.
15. Benacerraf BR, Harlow B, Frigoletto FD. Are choroid plexus cysts an indication for second-trimester amniocentesis? Am J Obstet Gynecol 1990; 162:1001-6.
16. Wald NJ, Kennard A. Prenatal biochemical screening for Down syndrome and neural tube defects. Curr Opin Obstet Gynecol 1992;4:3027.
17. Palomaki GE, Knight GJ, McCarthy J, et al. Maternal serum screening for fetal Down syndrome in the United States: a 1992 survey. Am J Obstet Gynecol 1993; 169:1558-62.
18. Benacerraf BR, Nadel A, Bromley B. Identification of second-trimester fetuses with autosomal trisomy by use of a sonographic scoring index. Radiology 1994; 193:1350.
19. Ricketts NEM, Lowe EM, Patel NB: Prenatal diagnosis of choroid plexus cysts. Lancet 1987; 1:213-4.
20. Rotmensch S, Luo JS, Nores JA, Dimaio MS, Hobbins JC. Bilateral choroid plexus cysts in trisomy 21. Am J Obstet Gynecol 1992; 166: 591-2.
21. Thorpe-Beeston JG, Gosden CM, Nicolaides KH. Choroid plexus cysts and chromosomal defects. Br J Radiol 1990;63:783-6.
22. Zerres K, Schuler H, Gembruch U, et al. Chromosomal findings in fetuses with prenatally diagnosed cysts of the choroid plexus. Hum Genet 1992;89:301-4.
23. Perpignano MC, Cohen HL, Klein VR, et al. Fetal choroid plexus cysts: beware the smaller cyst. Radiology 1992; 182:715-7.
24. Porto M, Murata Y, Warneke LA, et al. Fetal choroid plexus cysts: an independent risk factor for chromosomal anomalies. J Clin Ultrasound 1993;21:103-8.
25. Kennedy KA, Carey JC. Choroid plexus cysts: significance and current management practices. Semin Ultrasound CT MR 1993:14:23-30.
26. Walkinshaw S, Pilling D, Spriggs A. Isolated choroid plexus cyststhe need for routine offer of karyotyping. Prenat Diagn 1994; 14:663-7.