Ectopic activation of Dpp signalling in the male Drosophila germline inhibits germ cell differentiation

Genesis (United States)

Volumn 39, Issue 2, 2004, Pages 84-93

  Bunt, Stephanie M ^b   Hime, Gary R ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b NONE

Author keywords

Drosophila; Stem cell; Testis; TGF

Indexed keywords

ACTIVIN; CELL MARKER; CELL PROTEIN; DAD PROTEIN; DECAPENTAPLEGIC RECEPTOR; RECEPTOR; STEM CELL MARKER; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL POPULATION; DROSOPHILA; ECTOPIC SIGNALING; GENE EXPRESSION; GERM CELL; GERM CELL DIFFERENTIATION; GERM LINE; MALE; MICROENVIRONMENT; NEWBORN; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SOMATIC CELL; SPERMATOGONIUM; SPERMATOGONIUM LIKE CELL; STEM CELL; TESTIS;

EID: 3142668991     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.20030     Document Type: Article

References (47)

1. Austin J, Kimble J. 1987. glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans. Cell 51:589-599.
2. Berry LW, Westlund B, Schedl T. 1997. Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors. Development 124:925-936.
3. Brummel T, Abdollah S, Haerry TE, Shimell MJ, Merriam J, Raftery L, Wrana JL, O'Connor MB. 1999. The Drosophila activin receptor baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development. Genes Dev 13:98-111.
4. Chen D, McKearin D. 2003a. Dpp signaling silences bam transcription directly to establish asymmetric divisions of germline stem cells. Curr Biol 13:1786-1791.
5. Chen D, McKearin DM. 2003b. A discrete transcriptional silencer in the bam gene determines asymmetric division of the Drosophila germ-line stem cell. Development 130:1159-1170.
6. de Cuevas M, Spradling AC. 1998. Morphogenesis of the Drosophila fusome and its implications for oocyte specification. Dev Suppl 125:2781-2789.
7. Fuller MT. 1993. Spermatogenesis. In: Bate M, Martinez Arrias A, editors. The development of Drosophila melanogaster, vol. 1. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. p 71-147.
8. Fuller MT. 1998. Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis. Semin Cell Dev Biol 9:433-444.
9. Gonczy P, DiNardo S. 1996. The germ line regulates somatic cyst cell proliferation and fate during Drosophila spermatogenesis. Development 122:2437-2447.
10. Gonczy P, Viswanathan S, DiNardo S. 1992. Probing spermatogenesis in Drosophila with P-element enhancer detectors. Development 114:89-98.
11. Gonczy P, Matunis E, DiNardo S. 1997. bag-of-marbles and benign gonial cell neoplasm act in the germline to restrict proliferation during Drosophila spermatogenesis. Development 124:4361-4371.
12. Goodman CS, Doe CQ. 1993. Embryonic development of the Drosophila central nervous system. In: Bate M, Martinez Arrias A, editors. The development of Drosophila melanogaster, vol. 2. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. p 1131-1206.
13. Haerry T, Khalsa O, O'Connor M, Wharton K. 1998. Synergistic signaling by two BMP ligands through the SAX and TKV receptors controls wing growth and patterning in Drosophila. Development 125:3977-3987.
14. Hardy RW, Tokuyasu KT, Lindsley DL, Garavito M. 1979. The germinal proliferation centre in the testis of Drosophila. J Ultrastruct Res 69:180-190.
15. Henderson S, Gao D, Lambie E, Kimble J. 1994. lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans. Development 120:2913-2924.
16. Kemphues KJ, Raff EC, Raff RA, Kaufman TC. 1980. Mutation in a testis-specific beta-tubulin in Drosophila: analysis of its effects on meiosis and map location of the gene. Cell 21:445-451.
17. Kiger AA, Fuller MT. 2001. Male germ-line stem cells. In: Marshak DR, Gardner RL, Gottlieb D, editors. Stem cell biology. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. p 149-187.
18. Kiger AA, White-Cooper H, Fuller MT. 2000. Somatic support cells restrict germline stem cell self-renewal and promote differentiation. Nature 407:750-754.
19. Kiger AA, Jones DL, Schulz C, Rogers MB, Fuller MT. 2001. Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue. Science 294:2542-2545.
20. Kimble JE, White JG. 1981. On the control of germ cell development in Caenorhabditis elegans. Dev Biol 81:208-219.
21. King FJ, Lin H. 1999. Somatic signaling mediated by fs(1)Yb is essential for germline stem cell maintenance during Drosophila oogenesis. Dev Suppl 126:1833-1844.
22. Lasko PF, Ashburner M. 1990. Posterior localization of vasa protein correlates with, but is not sufficient for, pole cell development. Genes Dev 4:905-921.
23. Lin H. 1997. The tao of stem cells in the germline. Annu Rev Genet 31:455-491.
24. Lin H, Spradling A. 1993. Germline stem cell division and egg chamber development in transplanted Drosophila germaria. Dev Biol 159:140-152.
25. Lin H, Spradling A. 1997. A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary. Development 124:2463-2476.
26. Lin H, Yue L, Spradling A. 1994. The Drosophila fusome, a germline-specific organelle, contains membrane skeletal proteins and functions in cyst formation. Development 120:947-956.
27. Margolis J, Spradling A. 1995. Identification and behavior of epithelial stem cells in the Drosophila ovary. Dev Suppl 121:3797-3807.
28. Matunis E, Tran J, Gonczy P, Caldwell K, DiNardo S. 1997. punt and schnurri regulate a somatically derived signal that restricts proliferation of committed progenitors in the germline. Development 124:4383-4391.
29. McKearin D, Ohlstein B. 1995. A role for the Drosophila bag-of-marbles protein in the differentiation of cystoblasts from germline stem cells. Development 121:2937-2947.
30. Meng X, Lindahl M, Hyvonen ME, Parvinen M, de Rooij DG, Hess MW, Raatikainen-Ahokas A, Sainio K, Rauvala H, Lakso M, et al. 2000. Regulation of cell fate decision of undifferentiated spermatogonia by GDNF. Science 287:1489-1493.
31. Raftery LA, Sutherland DJ. 1999. TGF-beta family signal transduction in Drosophila development: from Mad to Smads. Dev Biol 210:251-268.
32. Rasmussen SW. 1973. Ultrastructural studies of spermatogenesis in Drosophila melanogaster Meigen. Zeitschr Zellfors Mikroskop Anat 140:125-144.
33. Schulz C, Wood CG, Jones DL, Tazuke SI, Fuller MT. 2002. Signaling from germ cells mediated by the rhomboid homolog stet organizes encapsulation by somatic support cells. Development 129:4523-4534.
34. Spradling A, Drummond-Barbosa D, Kai T. 2001. Stem cells find their niche. Nature 414:98-104.
35. Streit A, Bernasconi L, Sergeev P, Cruz A, Steinmann-Zwicky M. 2002. mgml, the earliest sex-specific germline marker in Drosophila, reflects expression of the gene esg in male stem cells. Int J Dev Biol 46:159-166.
36. Tazuke SI, Schulz C, Gilboa L, Fogarty M, Mahowald AP, Guichet A, Ephrussi A, Wood CG, Lehmann R, Fuller MT. 2002. A germline-specific gap junction protein required for survival of differentiating early germ cells. Development 129:2529-2539.
37. Tracey, WD Jr, Ning X, Klingler M, Kramer SG, Gergen JP. 2000. Quantitative analysis of gene function in the Drosophila embryo. Genetics 154:273-284.
38. Tran J, Brenner TJ, DiNardo S. 2000. Somatic control over the germline stem cell lineage during Drosophila spermatogenesis. Nature 407:754-757.
39. Tsuneizumi K, Nakayama T, Kamoshida Y, Kornberg TB, Christian JL, Tabata T. 1997. Daughters against dpp modulates dpp organizing activity in Drosophila wing development. Nature 389:627-631.
40. Tulina N, Matunis E. 2001. Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling. Science 294:2546-2549.
41. Twombly V, Blackman RK, Jin H, Graff JM, Padgett RW, Gelbart WM. 1996. The TGF-beta signaling pathway is essential for Drosophila oogenesis. Development. 122:1555-1565.
42. Van Doren M, Williamson AL, Lehmann R. 1998. Regulation of zygotic gene expression in Drosophila primordial germ cells. Curr Biol 8:243-246.
43. Whiteley M, Noguchi PD, Sensabaugh SM, Odenwald WF, Kassis JA. 1992. The Drosophila gene escargot encodes a zinc finger motif found in snail-related genes. Mech Dev 36:117-127.
44. Wodarz A. 2001. Cell polarity: no need to reinvent the wheel. Curr Biol 11:R975-978.
45. Xie T, Spradling AC. 1998. decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary. Cell 94:251-260.
46. Xie T, Spradling AC. 2000. A niche maintaining germ line stem cells in the Drosophila ovary. Science 290:328-330.
47. Yoshinaga K, Nishikawa S, Ogawa M, Hayashi S, Kunisada T, Fujimoto T. 1991. Role of c-kit in mouse spermatogenesis: identification of spermatogonia as a specific site of c-kit expression and function. Development 113:689-699.