Transformation of diffuse large B-cell lymphoma into pre-B acute lymphoblastic leukemia: Clinicopathologic features and clonal relationship

Human Pathology

Volumn 35, Issue 7, 2004, Pages 900-903

  Au, W Y ^a   Srivastava, G ^a   Wong, K Y ^a   Chung, L P ^a   Ma, S K ^a   Wan, T S ^a   Kwong, Y L ^a  

^a QUEEN MARY HOSPITAL   (Hong Kong)

Author keywords

acute lymphoblastic leukemia; ALL; clonal evolution; diffuse large B cell lymphoma; DLBC; EBER; Epstein Barr virus expressed RNA; IgH; immunoglobulin heavy chain; PCR; polymerase chain reaction; Tdt

Indexed keywords

CD19 ANTIGEN; CD20 ANTIGEN; CD22 ANTIGEN; CD34 ANTIGEN; CD79A ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; BIOTRANSFORMATION; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE COURSE; FIBROSIS; GENE MUTATION; HUMAN; LARGE CELL LYMPHOMA; LUNG ALVEOLITIS; MOLECULAR CLONING; PRECURSOR;

AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BASE SEQUENCE; CELL TRANSFORMATION, NEOPLASTIC; CLONE CELLS; DNA, NEOPLASM; FATAL OUTCOME; FEMALE; HUMANS; IMMUNOPHENOTYPING; IN SITU HYBRIDIZATION; KARYOTYPING; LEUKEMIA, B-CELL, ACUTE; LYMPHOMA, B-CELL; LYMPHOMA, LARGE-CELL, DIFFUSE; MOLECULAR SEQUENCE DATA; NEOPLASMS, SECOND PRIMARY; RIBOSOMAL PROTEINS; RNA, NEOPLASM; RNA, VIRAL; RNA-BINDING PROTEINS;

EID: 3142634593     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2004.04.002     Document Type: Article

References (15)

1. de Jong D., Glas A.M., Boerrigter L., et al. Very late relapse in diffuse large B-cell lymphoma represents clonally related disease and is marked by germinal center cell features. Blood. 102:2003;324-327
2. Foon K.A., Thiruvengadam R., Saven A., et al. Genetic relatedness of lymphoid malignancies. Transformation of chronic lymphocytic leukemia as a model. Ann Intern Med. 119:1993;63-73
3. Martinez-Climent J.A., Alizadeh A.A., Segraves R., et al. Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations. Blood. 101:2003;3109-3117
4. Traweek S.T., Liu J., Johnson R.M., et al. High-grade transformation of chronic lymphocytic leukemia and low-grade non-Hodgkin's lymphoma. Genotypic confirmation of clonal identity. Am J Clin Pathol. 100:1993;519-526
5. Nishiuchi R., Yoshino T., Teramoto N., et al. Clonal analysis by polymerase chain reaction of B-cell lymphoma with late relapse A report of five cases. Cancer. 77:1996;757-762
6. Jaffe E.S., Harris N.L., Stein H., et al. World Health Organization Classification of Tumors Tumors of Hematopoietic and Lymphoid Tissues. 2001;IARC Press, Lyon, France
7. Au W.Y., Shek W.H., Nicholls J., et al. T-cell intravascular lymphomatosis (angiotropic large cell lymphoma) Association with Epstein-Barr viral infection. Histopathology. 31:1997;563-567
8. McCarthy K.P., Sloane J.P., Wiedemann L.M. Rapid method for distinguishing clonal from polyclonal B-cell populations in surgical biopsy specimens. J Clin Pathol. 43:1990;429-432
9. Wetzler M., Kurzrock R., Goodacre A.M., et al. Transformation of chronic lymphocytic leukemia to lymphoma of true histiocytic type. Cancer. 76:1995;609-617
10. Kroft S.H., Dawson D.B., McKenna R.W. Large-cell lymphoma transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma. A flow cytometric analysis of seven cases. Am J Clin Pathol. 115:2001;385-395
11. Miyamura K., Osada H., Yamauchi T., et al. Single clonal origin of neoplastic B-cells with different immunoglobulin light chains in a patient with Richter's syndrome. Cancer. 66:1990;140-144
12. Pistoia V., Roncella S., Di Celle P.F., et al. Emergence of a B-cell lymphoblastic lymphoma in a patient with B-cell chronic lymphocytic leukemia Evidence for the single-cell origin of the two tumors. Blood. 78:1991;797-804
13. Bahler D.W., Swerdlow S.H. Clonal salivary gland infiltrates associated with myoepithelial sialadenitis (Sjögren's syndrome) begin as nonmalignant antigen-selected expansions. Blood. 91:1998;1864-1872
14. Stott D.I., Hiepe F., Hummel M., et al. Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjögren's syndrome. J Clin Invest. 102:1998;938-946
15. Szczepek A.J., Bergsagel P.L., Axelsson L., et al. CD34+ cells in the blood of patients with multiple myeloma express CD19 and IgH mRNA and have patient-specific IgH VDJ gene rearrangements. Blood. 89:1997;1824-1833