Phospholipase C involvement in activation of the muscarinic receptor-operated cationic current in guinea pig ileal smooth muscle cells

Journal of Pharmacological Sciences

Volumn 95, Issue 2, 2004, Pages 203-213

  Okamoto, Hiroyuki ^a   Unno, Toshihiro ^a   Arima, Daisuke ^a   Suzuki, Maki ^a   Yan, Hai Dun ^a   Matsuyama, Hayato ^a   Nishimura, Masakazu ^a   Komori, Seiichi ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

Diacylgrycerol; Muscarinic receptor; Nonselective cationic current; Phospholipase C; Smooth muscle

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; ANTIBODY; CARBACHOL; DIACYLGLYCEROL DERIVATIVE; G(Q) PROTEIN; GALPHA 11 PROTEIN; GLYCEROL 2 ACETATE 1 OLEATE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MUSCARINIC AGENT; MUSCARINIC RECEPTOR; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CATION TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; GUINEA PIG; ILEUM; ION CURRENT; NONHUMAN; PROTEIN FUNCTION; SMOOTH MUSCLE FIBER; VOLTAGE CLAMP;

EID: 3142622820     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.FP0030635     Document Type: Article

References (38)

1. Benham CD, Bolton TB, Lang RJ. Acetylcholine activates an inward current in single mammalian smooth muscle cells. Nature. 1985;316:345-347.
2. Inoue R, Isenberg G. Acetylcholine activates nonselective cation channels in guinea pig ileum through a G protein. Am J Physiol. 1990;258:C1173-C1178.
3. Bolton TB. Mechanisms of action of transmitters and other substances on smooth muscle. Physiol Rev. 1979;59:606-718.
4. Unno T, Kwon SC, Okamoto H, et al. Receptor signaling mechanisms underlying muscarinic agonist-evoked contraction in guinea-pig ileal longitudinal smooth muscle. Br J Pharmacol. 2003;139:337-350.
5. Zholos AV, Bolton TB. Muscarinic receptor subtypes controlling the cationic current in guinea-pig ileal smooth muscle. Br J Pharmacol. 1997;122:885-893.
6. Komori S, Unno T, Nakayama T, Ohashi H. M2 and M3 muscarinic receptors couple, respectively, with activation of nonselective cationic channels and potassium channels in intestinal smooth muscle cells. Jpn J Pharmacol. 1998;76:213-218.
7. Rhee JC, Rhee PL, Park MK, et al. Muscarinic receptors controlling the carbachol-activated nonselective cationic current in guinea pig gastric smooth muscle cells. Jpn J Pharmacol. 2000;82:331-337.
8. Komori S, Kawai M, Takewaki T, Ohashi H. GTP-binding protein involvement in membrane currents evoked by carbachol and histamine in guinea-pig ileal muscle. J Physiol (Lond). 1992;450:105-126.
9. 2+ channel current in smooth muscle cells of guinea-pig ileum. J Physiol (Lond). 1995;484:567-581.
10. 2+ current in guinea pig ileal smooth muscle cells. Eur J Pharmacol. 1998;346:323-330.
11. Kim YC, Kim SJ, Sim JH, et al. Suppression of the carbachol-activated nonselective cationic current by antibody against alpha subunit of Go protein in guinea-pig gastric myocytes. Pflugers Arch. 1998;436:494-496.
12. Yan HD, Okamoto H, Unno T, et al. Effects of G-protein-specific antibodies and G-βγ subunits on the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells. Br J Pharmacol. 2003;139:605-615.
13. Inoue R, Isenberg G. Intracellular calcium ions modulate acetylcholine-induced inward current in guinea-pig ileum. J Physiol (Lond). 1990;424:73-92.
14. Pacaud P, Bolton TB. Relation between muscarinic receptor cationic current and internal calcium in guinea-pig jejunal smooth muscle cells. J Physiol (Lond). 1991;441:477-499.
15. Zholos AV, Bolton TB. G-protein control of voltage dependence as well as gating of muscarinic metabotropic channels in guinea-pig ileum. J Physiol (Lond). 1994;478:195-202.
16. 3 receptor in longitudinal smooth muscle of guinea-pig small intestine. Br J Pharmacol. 2002; 135:1765-1775.
17. Helliwell RM, Large WA. Alpha 1-adrenoceptor activation of a non-selective cation current in rabbit portal vein by 1,2-diacyl-sn-glycerol. J Physiol (Lond). 1997;499:417-428.
18. Lee YM, Kim BJ, Kim HJ, et al. TRPC5 as a candidate for the nonselective cation channel activated by muscarinic stimulation in murine stomach. Am J Physiol Gastrointest Liver Physiol. 2003;284:G604-G616.
19. Zholos AV, Bolton TB. Effects of divalent cations on muscarinic receptor cationic current in smooth muscle from guinea-pig small intestine. J Physiol (Lond). 1995;486:67-82.
20. Komori S, Kawai M, Pacaud P, Ohashi H, Bolton TB. Oscillations of receptor-operated cationic current and internal calcium in single guinea-pig ileal smooth muscle cells. Pflugers Arch. 1993;424:431-438.
21. 2+ influx in single intestinal smooth muscle cells. Br J Pharmacol. 1996;19:245-252.
22. Bleasdale JE, Thakur NR, Gremban RS, et al. Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils. J Pharmacol Exp Ther. 1990;255:756-768.
23. 2+ oscillations in response to cholecystokinin and carbachol but not to JMV-180 in rat pancreatic acinar cells. J Biol Chem. 1992;267:13830-13835.
24. Smallridge RC, Kiang JG, Gist ID, Fein HG, Galloway RJ. U-73122, an aminosteroid phospholipase C antagonist, non-competitively inhibits thyrotropin-releasing hormone effects in GH3 rat pituitary cells. Endocrinology. 1992;131:1883-1888.
25. Komori S, Bolton TB. Calcium release induced by inositol 1,4,5-trisphosphate in single rabbit intestinal smooth muscle cells. J Physiol (Lond). 1991;433:495-517.
26. Tsien RY. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 1980;19: 2396-2404.
27. 2-channel interaction. Br J Pharmacol. 2001;134:1066-1072.
28. Smith RJ, Sam LM, Justen JM, Bundy GL, Bala GA, Bleasdale JE. Receptor-coupled signal transduction in human polymorphonuclear neutrophils: effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness. J Pharmacol Exp Ther. 1990;253:688-697.
29. Zholos AV, Bolton TB. A novel GTP-dependent mechanism of ileal muscarinic metabotropic channel desensitization. Br J Pharmacol. 1996;119:997-1012.
30. Kim SJ, Ahn SC, So I, Kim KW. Quinidine blockade of the carbachol-activated nonselective cationic current in guinea-pig gastric myocytes. Br J Pharmacol. 1995;115:1407-1414.
31. Berridge MJ. Inositol trisphosphate and diacylglycerol as second messengers. Biochem J. 1984;220:345-360.
32. Rhee SG, Suh PG, Ryu SH, Lee SY. Studies of inositol phospholipid- specific phospholipase C. Science. 1989;244:546-550.
33. 2+ release in single smooth muscle cells of guinea-pig small intestine. J Physiol (Lond). 1994;481:97-109.
34. Park D, Jhon DY, Lee CW, Lee KH, Rhee SG. Activation of phospholipase C isozymes by G protein beta gamma subunits. J Biol Chem. 1993;268:4573-4576.
35. Rhee SG. Regulation of phosphoinositide-specific phospholipase C. Annu Rev Biochem. 2001;70:281-312.
36. Inoue R, Waniishi Y, Yamada K, Ito Y. A possible role of tyrosine kinases in the regulation of muscarinic receptor-activated cation channels in guinea pig ileum. Biochem Biophys Res Commun. 1994;203:1392-1397.
37. Minke B, Cook B. TRP channel proteins and signal transduction. Physiol Rev. 2002;82:429-472.
38. Unno T, Sakamoto T, Arima D, et al. Both M2 and M3 receptor subtypes are indispensable for activation of the muscarinic receptor-operated cation channels in mouse intestinal smooth muscle cells. J Pharmacol Sci. 2004;94 Suppl I:101P.