Phosphorylation of AfsR by multiple serine/threonine kinases in Streptomyces coelicolor A3(2)

Gene

Volumn 334, Issue 1-2, 2004, Pages 53-61

  Sawai, Reiko ^a   Suzuki, Ayano ^a   Takano, Yuji ^a   Lee, Ping Chin ^a,b   Horinouchi, Sueharu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITI MALAYSIA SABAH   (Malaysia)

Author keywords

a.a.; Actinorhodin; amino acid(s); Antibiotic production; base pair(s); bp; PCR; polymerase chain reaction; Signal transduction; Transcriptional factor

Indexed keywords

ACTINORHODINE; AMINO ACID; HISTIDINE; PHOSPHOTRANSFERASE; PROTEIN AFSK; PROTEIN AFSL; PROTEIN AFSR; PROTEIN AFSS; PROTEIN DERIVATIVE; PROTEIN PKAG; PROTEIN SERINE THREONINE KINASE; REGULATOR PROTEIN; SERINE; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; ARTICLE; AUTOPHOSPHORYLATION; BACTERIAL CHROMOSOME; BACTERIAL GROWTH; BACTERIAL METABOLISM; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ESCHERICHIA COLI; EUKARYOTE; GENE DISRUPTION; GENETIC CODE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; STREPTOMYCES COELICOLOR; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANTHRAQUINONES; BACTERIAL PROTEINS; BASE SEQUENCE; DNA-BINDING PROTEINS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOMYCES; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ESCHERICHIA COLI; EUKARYOTA; STREPTOMYCES; STREPTOMYCES COELICOLOR;

EID: 3142600895     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2004.02.046     Document Type: Article

References (28)

1. Beck E., Ludwig G., Auerswald E.A., Reiss B., Schaller H. Nucleotide sequence and exact localization of the neomycin phosphotransferase gene from transposon Tn5. Gene. 19:1982;327-336
2. Bentley S.D., et al. Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature. 417:2002;141-147
3. Cooper J.A., Sefton B.M., Hunter T. Detection and quantification of phosphotyrosine in proteins. Methods Enzymol. 99:1983;387-402
4. Floriano B., Bibb M. afsR is a pleiotropic but conditionally required regulatory gene for antibiotic production in Streptomyces coelicolor A3(2). Mol. Microbiol. 21:1996;385-396
5. Hanks S.K., Quinn A.M., Hunter T. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science. 241:1988;42-52
6. Hirakata T., Kieser H., Hopwood D.A., Urabe H., Ogawara H. Putative protein serine/threonine kinase genes are located in several positions on the chromosome of Streptomyces coelicolor A3(2). FEMS Microbiol. Lett. 159:1998;1-5
7. Hopwood D.A., Bibb M.J., Chater K.F., Kieser T., Bruton C.J., Kieser H.M., Lydiate D.J., Smith C.P., Ward J.M., Schrempf H. Genetic Manipulation of Streptomyces: a Laboratory Manual. 1985;The John Innes Foundation, Norwich, UK
8. Horinouchi S. AfsR as an integrator of signals that are sensed by multiple serine/threonine kinases in Streptomyces coelicolor A3(2). J. Ind. Microbiol. Biotech. 30:2003;462-467
9. Horinouchi S., Beppu T. Production in large quantities of actinorhodin and undecylprodigiosin induced by afsB in Streptomyces lividans. Agric. Biol. Chem. 48:1984;2131-2133
10. Kamps M.P., Sefton B.M. Acid and base hydrolysis of phosphoproteins bound to immobilon facilitates analysis of phosphoamino acids in gel-fractionated proteins. Anal. Biochem. 176:1989;22-27
11. Kelemen G.H., Brian P., Flärdh K., Chamberlin L., Chater K.F., Buttner M.J. Developmental regulation of transcription of whiE, a locus specifying the polyketide spore pigment in Streptomyces coelicolor A3(2). J. Bacteriol. 180:1998;2515-2521
12. Kennelly P.J., Potts M. Fancy meeting you here! A fresh look at "prokaryotic" protein phosphorylation. J. Bacteriol. 178:1996;4759-4764
13. Kim E.-S., Hong H.-J., Choi C.-Y., Cohen S.N. Modulation of actinorhodin biosynthesis in Streptomyces lividans by glucose repression of afsR2 gene transcription. J. Bacteriol. 183:2001;2198-2203
14. Lee P.-C., Umeyama T., Horinouchi S. afsS is a target of AfsR, a transcriptional factor with ATPase activity that globally controls secondary metabolism in Streptomyces coelicolor A3(2). Mol. Microbiol. 43:2002;1413-1430
15. Maniatis T., Fritsch E.F., Sambrook J. Molecular Cloning: A Laboratory Manual. 1982;Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
16. Matsumoto A., Hong S.-K., Ishizuka H., Horinouchi S., Beppu T. Phosphorylation of the AfsR protein involved in secondary metabolism in Streptomyces species by a eukaryotic-type protein kinase. Gene. 146:1994;47-56
17. Neu J.M., MacMillan S.V., Nodwell J.R., Wright G.D. StoPK-1, a serine/threonine protein kinase from the glycopeptide antibiotic producer Streptomyces toyocaensis NRRL 15009, affects oxidative stress response. Mol. Microbiol. 44:2002;417-430
18. Ogawara H., Aoyagi N., Watanabe M., Urabe H. Sequences and evolutionary analyses of eukaryotic-type protein kinases from Streptomyces coelicolor A3(2). Microbiology. 145:1999;3343-3352
19. Oh S.H., Chater K.F. Denaturation of circular or linear DNA facilitates targeted integrative transformation of Streptomyces coelicolor A3(2): possible relevance to other organisms. J. Bacteriol. 179:1997;122-127
20. Strohl W.R. Compilation and analysis of DNA sequences associated with apparent streptomycete promoters. Nucleic Acids Res. 20:1992;961-974
21. Sollner-Webb B., Reeder R.H. The nucleotide sequence of the initiation and termination sites for ribosomal RNA transcription in X. laevis. Cell. 18:1979;485-499
22. Umeyama T., Horinouchi S. Autophosphorylation of a bacterial serine/threonine kinase, AfsK, is inhibited by KbpA, an AfsK-binding protein. J. Bacteriol. 183:2001;5506-5512
23. Umeyama T., Lee P.-C., Ueda K., Horinouchi S. An AfsK/AfsR system involved in the response of aerial mycelium formation to glucose in Streptomyces griseus. Microbiology. 145:1999;2281-2292
24. Umeyama T., Lee P.-C., Horinouchi S. Protein serine/threonine kinases in signal transduction for secondary metabolism and morphogenesis in Streptomyces. Appl. Microbiol. Biotechnol. 59:2002;419-425
25. Vögtli M., Chang P.C., Cohen S.N. afsR2: a previously undetected gene encoding a 63-amino-acid protein that stimulates antibiotic production in Streptomyces lividans. Mol. Microbiol. 14:1994;643-653
26. Wietzorrek A., Bibb M. A novel family of proteins that regulates antibiotic production in streptomycetes appears to contain an OmpR-like DNA-binding fold. Mol. Microbiol. 25:1997;1181-1184
27. AdsA) that is essential for morphological development in Streptomyces griseus. J. Bacteriol. 182:2000;4596-4605
28. Zhang C.-C. Bacterial signalling involving eukaryotic-type protein kinases. Mol. Microbiol. 20:1996;9-15