Influence of high-dose leucovorin and 5-fluorouracil chemotherapy regimen on P wave duration and dispersion

Journal of Clinical Pharmacy and Therapeutics

Volumn 29, Issue 3, 2004, Pages 267-271

  Ceyhan, C ^a   Meydan, N ^a   Barutca, S ^a   Tekten, T ^a   Onbasili, A O ^a   Ozturk, B ^a   Unal, S ^a   Bayrak, I ^a  

^a ADNAN MENDERES UNIVERSITY   (Turkey)

Author keywords

Cardiotoxicity; Fluorouracil; P dispersion

Indexed keywords

ANTINEOPLASTIC AGENT; FLUOROURACIL; FOLINIC ACID;

ADULT; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CARCINOID; CARDIOTOXICITY; CLINICAL ARTICLE; COLORECTAL CARCINOMA; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG DOSE REGIMEN; DRUG MEGADOSE; ECG ABNORMALITY; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; HUMAN; MALE; P WAVE; STATISTICAL SIGNIFICANCE; STOMACH CARCINOMA;

AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOID TUMOR; CARCINOMA; COLORECTAL NEOPLASMS; CORONARY ARTERIOSCLEROSIS; CORONARY VASOSPASM; CORONARY VESSELS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; FLUOROURACIL; HUMANS; INFUSIONS, INTRAVENOUS; INJECTIONS, INTRAVENOUS; LEUCOVORIN; MALE; STOMACH NEOPLASMS; TIME FACTORS;

EID: 3142547219     PISSN: 02694727     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2710.2004.00556.x     Document Type: Article

References (36)

1. Labianca R, Beretta G, Clerici M, Fraschini P, Luporini G (1982) Cardiac toxicity of 5-fluorouracil: a study on 1083 patients. Tumori, 68, 505-510.
2. Robben NC, Pippas AW, Moore JO (1993) The syndrome of 5-fluorouracil cardiotoxicity: an elusive cardiopathy. Cancer, 71, 493-509.
3. Patel B, Kloner RA, Ensley J, Al Sarraf M, Kish J, Wyenne J (1987) 5-Fluorouracil cardiotoxicity. Left ventricular dysfunction and effect of coronary vasodilators. The American Journal of the Medical Sciences, 294, 238-243.
4. Weidmann B, Jansen W, Heider A, Niederle N (1995) 5-Fluorouracil cardiotoxicity with left ventricular dysfunction under different dosing regimens. The American Journal of Cardiology, 75, 194-195.
5. Schober C, Papageorgiou E, Harstrick A et al. (1993) Cardiotoxicity of 5-fluorouracil in combination with folinic acid in patients with gastrointestinal cancer. Cancer, 72, 2242-2247.
6. de Forni M, Malet-Martino MC, Jaillais P et al. (1992) Cardiotoxicity of high-dose continuous infusion fluorouracil: a prospective clinical study. Journal of Clinical Oncology, 10, 1795-1801.
7. Meyer CC, Calis KA, Burke LB, Walawander CA, Grasela TH (1997) Symptomatic cardiotoxicity associated with 5-fluorouracil. Pharmacotherapy, 17, 729-736.
8. Eskilsson J, Albertsson M, Mercke C (1988) Adverse cardiac effects during induction chemotherapy treatment with cis-platin and 5-fluorouracil. Radiotherapy, 13, 41-46.
9. Chaudary S, Song SYT, Jaski BE (1988) Profound, yet reversible, heart failure secondary to 5-fluorouracil. The American Journal of Medicine, 85, 454-456.
10. Dilaveris P, Gialafos EJ, Sideris S et al. (1998) Simple electrocardiographic markers for the prediction of paroxysmal idiopathic atrial fibrillation. American Heart Journal, 135, 733-738.
11. Dilaveris P, Gialafos JE (2001) P dispersion: a novel predictor of paroxysmal atrial fibrillation. Annals of Noninvasive Electrocardiology, 6, 159-165.
12. Surawicz B (1986) Electrocardiographic diagnosis of chamber enlargement. Journal of the American College of Cardiology, 3, 711-724.
13. Chandraratna PA, Hodges M (1973) Electrocardiographic diagnosis of left atrial hypertension in acute myocardial infarction. Circulation, 47, 493-498.
14. Weber UK, Osswald S, Huber M et al. (1998) Selective versus non-selective antiarrhythmic approach for prevention of atrial fibrillation after coronary surgery: is there a need for pre-operative risk stratification? A prospective placebo-controlled study using low dose sotalol. European Heart Journal, 19, 794.
15. Waggoner AD, Adyanthaya AV, Quinones MA, Alexander JK (1976) Left atrial enlargement: echocardiographic assessment of electrocardiographic criteria. Circulation, 4, 553-557.
16. Di Bianco ED, Gottdiener JS, Fletcher RD, Pipberger HV (1979) Left atrial overload: a hemodynamic, echocardiographic and vectorcardiographic study. American Heart Journal, 98, 478-489.
17. Myrianthefs MM, Ellestad MH, Startt-Selvester RH, Crump R (1991) Significance of signal-averaged P wave changes during exercise in patients with coronary artery disease and correlation with angiographic findings. The American Journal of Cardiology, 68, 1619-1624.
18. Pandya A, Ellestad MH, Crump R (1996) Time course of changes in P wave duration during exercise. Cardiology, 87, 343-346.
19. Myrianthefs MM, Shandling AH, Startt-Selvester RH et al. (1992) Analysis of signal averaged P wave duration in patients with percutaneous coronary angioplasty-induced coronary ischemia. The American Journal of Cardiology, 70, 728-732.
20. Heikkila J, Hugenholtz PG, Tabakin BS (1973) Prediction of left heart filling pressure and its sequential change in acute myocardial infarction from the terminal force of the P wave. British Heart Journal, 35, 142-151.
21. Steinberg JS, Zelenkofske S, Wong SC, Gelernt M, Sciacca R, Menchavez E (1993) Value of P wave signal averaged ECG for predicting atrial fibrillation after cardiac surgery. Circulation, 88, 2618-2622.
22. Aytemir K, Ozer N, Atalar E et al. (2000) P wave dispersion on 12-lead electrocardiography in patients with paroxysmal atrial fibrillation. Pacing and Clinical Electrophysiology, 23, 1109-1112.
23. Hashiba K, Tanigawa M, Fukatani M et al. (1989) Electrophysiologic properties of atrial muscle in paroxysmal atrial fibrillation. The American Journal of Cardiology, 64, 20J-23J.
24. Cosio FG, Palacios J, Vidal JM et al. (1983) Electrophysiologic studies in atrial fibrillation. Slow conduction of premature impulses: a possible manifestation of the background for reentry. The American Journal of Cardiology, 51, 122-130.
25. Simpson RJ, Foster JR, Gettes LS (1982) Atrial excitability and conduction defect. The American Journal of Cardiology, 50, 1331-1337.
26. Spach MS, Dolber PC (1986) Relating extracellular potentials and their derivatives to anisotropic propagation at a microscopic level in human cardiac muscle: evidence for electrical uncoupling of side-side fiber connections with increased age. Circulation Research, 58, 356-371.
27. Ciaroni S, Cuenoud L, Bloch A (2000) Clinical study to investigate the predictive parameters for the onset of atrial fibrillation in patients with essential hypertension. American Heart Journal, 139, 814-819.
28. Guidera SA, Steinberg JS (1993) The signal-averaged P wave duration: a rapid and noninvasive marker of risk of atrial fibrillation. Journal of the American College of Cardiology, 21, 1645-1651.
29. Kleiman NS, Lehane DE, Geyer CE, Jr, Pratt CM, Young JB (1987) Prinzmetal's angina during 5-fluorouracil chemotherapy. American Journal of Medicine, 82, 566-568.
30. Luwaert RJ, Descamps O, Majois F, Chaudron JM, Beauduin M (1991) Coronary artery spasm induced by 5-fluorouracil. European Heart Journal, 12, 468-470.
31. Lemaire L, Malet-Martino MC, de Forni M, Martino R, Laserre B (1992) Cardiotoxicity of commercial 5-fluorouracil vials stems from the alkaline hydrolysis of this drug. British Journal of Cancer, 1, 119-122.
32. Arellano M, Malet-Martino M, Martino R, Gires P (1998) The anti-cancer drug 5-fluorouracil is metabolized by the isolated perfused rat liver and in rats into highly toxic fluoroacetate. British Journal of Cancer, 1, 79-86.
33. Dilaveris PE, Andrikopoulos GK, Metaxas G et al. (1999) Effects of ischemia on P wave dispersion and maximum P wave duration during spontaneous anginal episodes. Pacing and Clinical Electrophysiology, 22, 1640-1647.
34. Barry WH, Brooker JZ, Alderman EL, Harrison DC (1974) Changes in diastolic stiffness and tone of left ventricle during angina pectoris. Circulation, 12, 255-263.
35. Wiener L, Dwyer EM Jr, Cox JW (1968) Left ventricular hemodynamics in exercise-induced angina pectoris. Circulation, 38, 240-249.
36. Alleissie MA, Bonke FI, Schopman FJG (1976) Circus movement in rabbit atrial muscle as a mechanism of tachycardia, II: the role of nonuniform recovery of excitability in the occurrence of unidirectional block as studied with multiple microelectrodes. Circulation Research, 39, 168-177.