Characteristics, epidemiology and clinical importance of emerging strains of Gram-negative bacilli producing extended-spectrum β-lactamases

Research in Microbiology

Volumn 155, Issue 6, 2004, Pages 409-421

  Shah, Aamer Ali ^a   Hasan, Fariha ^a   Ahmed, Safia ^a   Hameed, Abdul ^a  

^a QUAID I AZAM UNIVERSITY   (Pakistan)

Author keywords

Escherichia coli; Extended spectrum lactamases; Klebsiella pneumoniae; Pseudomonas aeruginosa

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AZTREONAM; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CARBAPENEM; CARBENICILLIN; CEFOTAXIME; CEFPODOXIME; CEFTAZIDIME; CEPHALOSPORIN; CLAVULANIC ACID; CLOXACILLIN; PENICILLIN G; PIPERACILLIN PLUS TAZOBACTAM; SULBACTAM; SULTAMICILLIN; TAZOBACTAM; TIMENTIN;

ANTIBIOTIC RESISTANCE; BACTERIAL INFECTION; BACTERIAL STRAIN; ENTEROBACTERIACEAE; EPIDEMIC; ESCHERICHIA COLI; EXPOSURE; GRAM NEGATIVE BACTERIUM; HOSPITAL COST; HOSPITALIZATION; HUMAN; INCIDENCE; KLEBSIELLA PNEUMONIAE; NONHUMAN; NUCLEOTIDE SEQUENCE; PREVALENCE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RISK FACTOR; SHORT SURVEY; UNINDEXED SEQUENCE;

ANTI-BACTERIAL AGENTS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; MICROBIAL SENSITIVITY TESTS;

BACILLI; BACTERIA (MICROORGANISMS); ENTEROBACTERIACEAE; ESCHERICHIA COLI; KLEBSIELLA; KLEBSIELLA PNEUMONIAE; NEGIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 3142532473     PISSN: 09232508     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resmic.2004.02.009     Document Type: Short Survey

References (92)

1. Afazal-Shah M., Woodford N., Livermore D.M. Characterization of OXA-25, OXA-26, and OXA-27, molecular class D β -lactamases associated with carbapenem resistance in clinical isolates of Acinetobacter baumanii. Antimicrob. Agents Chemother. 45:2001;583-588
2. Ambler R.P. The structure of β -lactamases. Philos. Trans. R Soc. London B. 289:1980;321-331
3. Arlet G., Brami G., Dècrère D., Flippo A., Galtolot O., Lagrange P.H., Philippon A. Molecular characterization by PCR-restriction fragment length polymorphism of TEM β -lactamases. FEMS Microbiol. Lett. 134:1995;1498-1500
4. Barroso H., Freitas-Vieira A., Lito L.M., Cristino J.M., Salgado M.J., Neto H.F., Sousa J.C., Soveral G., Moura T., Duarte A. Survey of Klebsiella pneumoniae producing extended-spectrum β -lactamases at a Portuguese hospital: TEM-10 as the endemic enzyme. J. Antimicrob. Chemother. 45:2000;611-616
5. Barthélémy M., Péduzzi J., Labia R. Distinction entre les structures primaries des β -lactamases TEM-1 et TEM-2. Ann. Inst. Pasteur Microbiol. A. 136:1985;311-321
6. Bermudes H., Arpin C., Jude F., El-Harrif Z., Bébéar C., Quentin C. Molecular epidemiology of an outbreak due to extended-spectrum β -lactamase-producing Enterobacteria in a French hospital. Eur. J. Clin. Microbiol. Infect. Dis. 16:1997;523-529
7. Blahova J., Kralikova K., Krcmery V. New aspects of antibiotic resistance and possibilities of its prevention. Cas. Lek. Cesk. 140:2001;487-491
8. Blondeau J.M. Extended-spectrum beta-lactamases. Semin. Respir. Infect. 16:2001;169-176
9. Bonfiglio G., Perilli M., Stefani S., Amicosante G., Nicoletti G. Prevalence of extended-spectrum β -lactamases among Enterobacteriaceae: An Italian survey. Int. J. Antimicrob. Agents. 19:2002;213-217
10. Bonnet P.R., Sampaio J.L.M., Labia R., De Champs C., Sirot D., Chanel C., Sirot J. A novel CTX-M β -lactamase (CTX-M-8) in cefotaxime-resistant Enterobacteriaceae isolated in Brazil. Antimicrob. Agents Chemother. 44:2000;1936-1942
11. Bonomo R.A., Rudin S.A., Shlaes D.M. Tazobactam is a potent inactivator of selected inhibitor-resistant class A β -lactamases. FEMS Microbiol. Lett. 148:1997;59-62
12. Bou G., Oliver A., Martínez-Beltrán J. OXA-24, a novel class D β -lactamase with carbapenemase activity in an Acinetobacter baumannii clinical strain. Antimicrob. Agents Chemother. 44:2000;1556-1561. 31
13. Bradford P.A., Urban C., Jaiswal A., Mariano N., Rasmussen B.A., Projan S.J., Rahal J.J., Bush K. SHV-7, a novel cefotaxime-hydrolyzing β -lactamase, identified in Escherichia coli isolates from hospitalized nursing home patients. Antimicrob. Agents Chemother. 39:1995;899-905
14. Bradford P.A., Yang Y., Sahm D., Grope I., Gardovska D., Storch G. CTX-M-5, a novel cefotaxime-hydrolyzing β -lactamase from an outbreak of Salmonella typhimurium in Latvia. Antimicrob. Agents Chemother. 42:1998;1980-1984
15. Branger C., Lesimple A.L., Bruneu B., Berry P., Lambert-Zechovsky N. Long-term investigation of the clonal dissemination of Klebsiella pneumoniae isolates producing extended-spectrum β -lactamases in a university hospital. J. Med. Microbiol. 47:1998;201-209
16. Bret L., Chanel C., Sirot D., Labia R., Sirot J. Characterization of an inhibitor-resistant enzyme IRT-2 derived from TEM-2 β -lactamase produced by Proteus mirabilis strains. J. Antimicrob. Chemother. 38:1996;183-191
17. Bryan L.E. General mechanisms of resistance to antibiotics. J. Antimicrob. Chemother. 22:(Suppl. A):1988;1-15
18. Bush K., Jacoby G.A., Medeiros A.A. A functional classification scheme for β -lactamases and its correlation with molecular structure. Antimicrob. Agents Chemother. 39:1995;1211-1233
19. Bush K., Jacoby G. Nomenclature of TEM β -lactamases. J. Antimicrob. Chemother. 40:1997;1-3
20. Bush K. New β -lactamases in Gram-negative bacteria: Diversity and impact on the selection of antimicrobial therapy. Clin. Infect. Dis. 32:2001;1085-1089
21. Casewell M.W., Phillips I. Hands as a route of transmission for Klebsiella species. Br. Med. J. 2:1977;1315-1317
22. Chaibi E.B., Sirot D., Paul G., Labia R. Inhibitor-resistant TEM- β -lactamases: Phenotypic, genetic and biochemical characteristics. J. Antimicrob. Chemother. 43:1999;447-458
23. Cormican M.G., Marshall S.A., Jones R.N. Detection of extended-spectrum β -lactamase (ESBL)-producing strains by the E-test ESBL screen. J. Clin. Microbiol. 34:1996;1880-1884
24. D'Agata E., Venkataraman L., DeGirolami P., Weigel L., Samore M., Tenover F. The molecular and clinical epidemiology of enterobacteriaceae-producing extended-spectrum β -lactamase in a tertiary care hospital. J. Infect. 36:1998;279-285
25. Danel F., Hall L.M.C., Duke B., Gur D., Livermore D.M. OXA-17, a further extended-spectrum variant of OXA-10 β -lactamase, isolated from Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 43:1999;1362-1366
26. Danel F., Hall L.M.C., Gur D., Livermore D.M. OXA-14, another extended-spectrum variant of OXA-10 (PSE-2) β -lactamase from Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 39:1995;1881-1884
27. Datt N., Kontomichalou P. Penicillinase synthesis controlled by infectious R-factor in Enterobacteriaceae. Nature. 208:1965;239-241
28. De Champs C., Sauvant M.P., Chanal C., Sirot D., Gazuy N., Malhuret R. Prospective survey of colonization and infections caused by expanded-spectrum β -lactamase-producing members of the family Enterobacteriaceae in an intensive care unit. J. Clin. Microbiol. 12:1989;2887-2890
29. Doucet-Populaire F., Ghnassia J.C., Bonnet R., Sirot J. First isolation of a CTX-M-3-producing Enterobacter cloacae in France. Antimicrob. Agents Chemother. 44:2000;3239-3240
30. El Harrif-Heraud Z., Arpin C., Benliman S., Quentin C. Molecular epidemiology of a nosocomial outbreak due to SHV-4 producing strains of Citrobacter diversus. J. Clin. Microbiol. 35:1997;2561-2567
31. Emery C.L., Weymouth L.A. Detection and clinical significance of extended-spectrum β -lactamases in a tertiary-care medical center. J. Clin. Microbiol. 35:1997;2061-2067
32. Gniadkowski M., Palucha A., Grzesioski P., Hryniewicz W. Outbreak of ceftazidime-resistant Klebsiella pneumoniae in a pediatric hospital in Warsaw, Poland: Clonal spread of the TEM-47 extended-spectrum β -lactamase (ESBL)-producing strain and transfer of a plasmid carrying the SHV-5-like ESBL-encoding gene. Antimicrob. Agents Chemother. 42:1998;3079-3085
33. Gniadkowski M., Schneider I., Palucha A., Jungwirth R., Mikiewicz B., Bauernfeind A. Cefotaxime-resistant Enterobacteriaceae isolates from a hospital in Warsaw, Poland: Identification of a new CTX-M-3 cefotaxime-hydrolyzing β -lactamase that is closely related to the CTX-M-1/MEN-1 enzyme. Antimicrob. Agents Chemother. 42:1998;827-832
34. Helfand M.S., Bonomo R.A. β -lactamases: A survey of protein diversity. Curr. Drug Targets Infect. Disord. 3:2003;9-23
35. Huovinen S., Huovinen P., Jacoby G.A. Detection of plasmid-mediated β -lactamases with DNA probes. Antimicrob. Agents Chemother. 32:1988;175-179
36. Jacoby G.A., Medeiros A.A. More extended-spectrum β -lactamases. Antimicrob. Agents Chemother. 35:1991;1697-1704
37. Jarlier V., Nicolas M.H., Fournier G., Philippon A. Extended-spectrum β -lactamases conferring transferable resistance to newer β -lactam agents in Enterobacteriaceae: Hospital prevalence and susceptibility patterns. Rev. Infect. Dis. 10:1988;867-878
38. Jonson A.P., Woodford N. Bacterial antibiotic resistance. Curr. Opin. Infect. Dis. 6:1993;515-519
39. Kim J., Kwon Y., Pai H., Kim J.W., Cho D.-T. Survey of Klebsiella pneumoniae strains producing extended-spectrum β -lactamases: Prevalence of SHV-12 and SHV-2a in Korea. J. Clin. Microbiol. 36:1998;1446-1449
40. Lautenbach E., Patel J.B., Bilker W.B., Edelstain P.H., Fishman N.O. Extended-spectrum β -lactamase-producing Escherichia coli and Klebsiella pneumoniae: Risk factors for infection and impact on resistance of outcomes. Clin. Infect. Dis. 32:2001;1162-1171
41. Livermore D.M. β -Lactamases in laboratory and clinical resistance. Clin. Microbiol. Rev. 8:1995;557-584
42. Mabilat C., Courvalin P. Development of "oligotyping" for characterization and molecular epidemiology of TEM β -lactamases in members of the family Enterobacteriaceae. Antimicrob. Agents Chemother. 34:1990;2210-2216
43. Marchandin H., Carriere C., Sirot D., Jean-Pierre H., Darbas H. TEM-24 produced by four different species of Enterobacteriaceae, including Providencia rettgeri, in a single patient. Antimicrob. Agents Chemother. 43:1999;2069-2073
44. Matsumoto Y., Inoue M. Characterization of SFO-1, a plasmid-mediated inducible class A β -lactamase from Enterobacter cloacae. Antimicrob. Agents Chemother. 43:1999;307-313
45. Matthew M. Plasmid-mediated β -lactamases of Gram-negative bacteria: Properties and distribution. J. Antimicrob. Chemother. 5:1979;349-358
46. Medeiros A., Mayer K.H., Opal S.M. Plasmid-mediated β -lactamases. Antimicrob. Newsl. 5:1988;61-65
47. Medeiros A. Evolution and dissemination of β -lactamases accelerated by generations of β -lactam antibiotics. Clin. Infect. Dis. 24:(Suppl. 1):1997;S19-S45
48. Morris D., O'Hare C., Glennon M., Maher M., Corbett-Feeney G., Cormican M. Extended-spectrum β -lactamases in Ireland, including a novel enzyme, TEM-102. Antimicrob. Agents Chemother. 47:2003;2572-2578
49. Mugnier P., Dubrous P., Casin I., Arlet G., Collatz E. A TEM-derived extended-spectrum β -lactamase in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 40:1996;2488-2493
50. Naas T., Philippon L., Poirel L., Ronco E., Nordman P. An SHV-derived extended-spectrum β -lactamase in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 43:1999;1281-1284
51. Naas T., Sougakoff W., Casetta A., Nordman P. Molecular characterization of OXA-20, a novel class D β -lactamase, and its integron from Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 42:1998;2074-2083
52. Naas T., Poirel L., Karim A., Nordmann P. Molecular characterization of In50, a class 1 integron encoding the gene for the extended-spectrum β -lactamase VEB-1 in Pseudomonas aeruginosa. FEMS Microbiol. Lett. 176:1999;411-419
53. Nathisuwan S., Burgess D.S., Lewis J.S. Extended-spectrum β -lactamases: Epidemiology, detection, and treatment. Pharmacotherapy. 21:2001;920-928
54. National Committee for Clinical Laboratory Standards, Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: Approved standard M7-A5 and informational supplement M100-S10, National Committee for Clinical Laboratory Standards, Wayne, PA, 2000
55. Nordman P., Ronco E., Naas T., Duport C., Michel-Briand Y., Labia R. Characterization of a novel extended-spectrum β -lactamase from Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 37:1993;962-969
56. Nordmann P. Trends in β -lactam resistance among Enterobacteriaceae. Clin. Infect. Dis. 27:1998;S100-S106
57. Nordmann P., Poirel L., Kubina M., Casetta A., Naas T. Biochemical-genetic characterization and distribution of OXA-22, a chromosomal and inducible class D β -lactamase from Ralstonia (Pseudomonas) pickettii. Antimicrob. Agents Chemother. 44:2000;2201-2204
58. Nüesch-Inderbinen M.T., Hächler F.H.K.H. Detection of genes coding for extended-spectrum SHV β -lactamases in clinical isolates by a molecular genetic method, and comparison with the E-test. Eur. J. Clin. Microbiol. Infect. Dis. 15:1996;398-402
59. Ouellette M., Paul G.C., Philippon A.M., Roy P.H. Oligonucleotide probes (TEM-1, OXA-1) versus isoelectric focusing in β -lactamase characterization of 114 resistant strains. Antimicrob. Agents Chemother. 32:1988;397-399
60. Pai H., Lyu S., Lee J.H., Kim J., Kwon Y., Kim J.W., Choe K.W. Survey of extended-spectrum β -lactamases in clinical isolates of Escherichia coli and Klebsiella pneumoniae: Prevalence of TEM-52 in Korea. J. Clin. Microbiol. 37:1999;1758-1763
61. Paterson D.L., Hujer K.M., Hujer A.M., Yeiser B., Bonomo M.D., Rice L.B., Bonomo R.A. Extended-spectrum β -lactamases in Klebsiella pneumoniae bloodstream isolates from seven countries: Dominance and widespread prevalence of SHV- and CTX-M-type β -lactamases. Antimicrob. Agents Chemother. 47:2003;3554-3560
62. Perilli M., Segatore B., Massis M.R.D., Riccio M.L., Bianchi C., Zollo A., Rossolini G.M., Amicosante G. TEM-72, a new extended-spectrum β -lactamase detected in Proteus mirabilis and Morganella morganii in Italy. Antimicrob. Agents Chemother. 44:2000;2537-2539
63. Philippon L.N., Naas T., Bouthors A.T., Barakett V., Nordmann P. OXA-18, a class D clavulanic acid-inhibited extended-spectrum β -lactamase from Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 41:1997;2188-2195
64. Poirel L., Thomas I.L., Naas T., Karim A., Nordman P. Biochemical sequence analyses of GES-1, a novel class A extended-spectrum β -lactamase, and the class 1 integron IN52 from Klebsiella pneumoniae. Antimicrob. Agents Chemother. 44:2000;622-632
65. Richmond M.H., Sykes R.B. The β -lactamases of Gram-negative bacteria and their possible physiological role. Adv. Microb. Physiol. 9:1973;31-88
66. Rosenau A., Cattier B., Gousset N., Harriau P., Philippon A., Quentin R. Capnocytophaga ochracea: Characterization of a plasmid-encoded extended-spectrum TEM-17 β -lactamase in the phylum Flavobacter-Bacteroides. Antimicrob. Agents Chemother. 44:2000;760-762
67. CME) encoding an extended-spectrum class A β -lactamase related to the Bacteroides cephalosporinases and the VEB-1 and PER β -lactamases. Antimicrob. Agents Chemother. 43:1999;2193-2199
68. Roy C., Foz A., Segura C., Tirado M., Funster C., Reig R. Plasmid-determined β -lactamases identified in a group of 204 ampicillin-resistant Enterobacteriaceae. J. Gen. Microbiol. 12:1983;507-510
69. Rupp M.E., Fey P.D. Extended-spectrum β -lactamase (ESBL)-producing enterobacteriaceae: Considerations for diagnosis, prevention and drug treatment. Drugs. 63:2003;353-365
70. Sanders C.C., Peyret M., Moland E.S., Shubert C., Thomson K.S., Boufgras J.M., Sanders W.E. Jr. Ability of the VITEK 2 Advanced Expert system to identify β -lactam phenotypes in isolates of Enterobacteriaceae and Pseudomonas aeruginosa. J. Clin. Microbiol. 38:2000;570-574
71. Shah A.A., Hasan F., Ahmed S., Hameed A. Extended-spectrum β -lactamases in Enterobacteriaceae: Related to age and gender. Microbiologia. 25:2002;363-366
72. Shah A.A., Hasan F., Ahmed S., Hameed A. Prevalence of extended-spectrum β -lactamases in nosocomial and outpatients. Pak. J. Med. Sci. 19:2003;187-191
73. Silva J., Aguilar C., Ayala G., Estrada M.A., Garza-Ramos U., Lara-Lemus R., Ledezma L. TLA-1: A new plasmid-mediated extended-spectrum β -lactamase from Escherichia coli. Antimicrob. Agents Chemother. 44:2000;997-1003
74. Simpson I.N., Harper P.B., O'Challaghan C.H. Principal β -lactamases responsible for resistance to β -lactam antibiotics in urinary tract infections. Antimicrob. Agents Chemother. 17:1980;926-936
75. Sirot D., Sirot J., Labia R., Morand A., Courvalin P., Parroux R. Transferable resistance to 3rd generation cephalosporins in clinical isolates of Klebsiella pneumoniae: Identification of CTX-1, a novel β -lactamase. J. Antimicrob. Chemother. 38:1987;323-334
76. Siu L.K., Lo J.Y.C., Yuen K.Y., Chau P.Y., Ng M.H., Ho P.L. β -Lactamases in Shigella flexneri isolates from Hong Kong and Shanghai and a novel OXA-1-like β -lactamase, OXA-30. Antimicrob. Agents Chemother. 44:2000;2034-2038
77. Sougakoff W., Goussard S., Courvalin P. The TEM-3 β -lactamase, which hydrolyzes broad-spectrum cephalosporins, is derived from the TEM-2 penicillinase by two amino acid substitutions. FEMS Microbiol. Lett. 56:1988;343-348
78. Spanu T., Luzzaro F., Perilli M., Amicosante G., Toniolo A., Fadda G. Occurrence of extended-spectrum β -lactamases in members of the family Enterobacteriaceae in Italy: Implications for resistance to beta-lactams and other antimicrobial drugs; Italian ESBL Study Group. Antimicrob. Agents Chemother. 46:2002;196-202
79. Stobberingh E.E., Arends J., Hoogkamp-Korstanje J.A.A., Goessens W.H.F., Visser M.R., Buiting A.G.M., Debets-Ossenkopp Y.J., Ketel R.J.V., Ogtrop M.L.V., Sabbe L.J.M., Voorn G.P., Winter H.L.J., Van Zeijl J.H. Occurrence of extended-spectrum β -lactamases in Dutch hospitals. Infection. 27:1999;348-354
80. Thomson K.S., Prevan A.M., Sanders C.C. β -Lactamases in Enterobacteriaceae: Emerging problem for new β -lactam antibiotics. Curr. Clin. Top. Infect. Dis. 16:1996;151-163
81. Thomson K.S., Sanders C.C. Detection of extended-spectrum β -lactamases in members of the family Enterobacteriaceae: Comparison of the double-disk and three-dimensional tests. Antimicrob. Agents Chemother. 36:1992;1877-1882
82. Tsang D.N.C., Que T.L., Ho M., Yuen K.Y. Comparison of screening methods for detection of extended-spectrum β -lactamases and their prevalence among Escherichia coli and Klebsiella species in Hong Kong. APMIS. 108:2000;237-240
83. Tzouvelekis L.S., Bonomo R.A. SHV-type β -lactamases. Curr. Pharm. Des. 5:1999;847-864
84. Tzouvelekis L.S., Tzelepi E., Tassios P.T., Legakis N.J. CTX-M-type β -lactamases: An emerging group of extended-spectrum enzymes. Int. J. Antimicrob. Agents. 14:2000;137-143
85. Vahaboglu H., Öztürk R., Aygün G., Coskunkan F., Yaman A., Kaygusuz A., Leblebicioglu H., Balik I., Aydin K., Otkun M. Widespread detection of PER-1-type extended-spectrum β -lactamases among nosocomial Acinetobacter and Pseudomonas aeruginosa isolates in Turkey: A nationwide multicenter study. Antimicrob. Agents Chemother. 41:1997;2265-2269
86. Vahaboglu H., Dodanli S., Eroglu C., Öztürk R., Soyletir G., Yildirim I., Avkan V. Characterization of multiple-antibiotic-resistant Salmonella typhimurium strains: Molecular epidemiology of PER-1-producing isolates and evidence for nosocomial plasmid exchange by a clone. J. Clin. Microbiol. 34:1996;2942-2946
87. Zali F.H., Gascoyne-Binzi D.M., Heritage J., Hawkey P.M. Detection of mutations conferring extended-spectrum activity on SHV β -lactamases using polymerase chain reaction single strand conformational polymorphism (PCR-SSCP). J. Antimicrob. Chemother. 37:1996;797-802
88. http://www.lahey.org/studies/temtable.asp. Lahey Clinic, TEM extended-spectrum and inhibitor-resistant β -lactameses
89. http://www.lahey.org/studies/webt.asp#SHV. Lahey Clinic, Amino acid sequences for TEM, SHV and OXA extended-spectrum and inhibitor-resistant β -lactameses
90. http://www.lahey.org/studies/other.asp#table1. Lahey Clinic, CTX-M-type β -lactameses
91. http://www.lahey.org/studies/webt.asp#OXA. Lahey Clinic, Amino acid sequences for TEM, SHV and OXA extended-spectrum and inhibitor-resistant β -lactameses
92. http://www.lahey.org/studies/other.asp#table1