Detection of mutations conferring extended-spectrum activity on SHV β-lactamases using polymerase chain reaction single strand conformational polymorphism (PCR-SSCP)

Journal of Antimicrobial Chemotherapy

Volumn 37, Issue 4, 1996, Pages 797-802

  M'Zali, Fatima Hannachi ^a   Gascoyne Binzi, Deborah M ^a   Heritage, John ^a   Hawkey, Peter M ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL ENZYME; BETA LACTAMASE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GENE; DRUG STRUCTURE; METHODOLOGY; NONHUMAN; POINT MUTATION; POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; STRUCTURE ACTIVITY RELATION;

BASE SEQUENCE; BETA-LACTAMASES; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE, MICROBIAL; HUMANS; ISOELECTRIC FOCUSING; MOLECULAR SEQUENCE DATA; POINT MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL;

EID: 0029913651     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/37.4.797     Document Type: Article

References (10)

1. Barthélémy, M., Péduzzi, J., Ben Yaghlane, H. & Labia, R. (1988). Single amino acid substitution between SHV-1 β-lactamase and cefotaxime-hydrolysing SHV-2 enzyme. FEBS Letters 231, 217-20.
2. Bure, A., Legrand, P., Arlet, G., Jarlier, V., Paul, G. & Philippon, A. (1988). Dissemination in five French hospitals of Klebsiella pneumoniae serotype K25 harbouring a new transferable enzymatic resistance to third generation cephalosporins and aztreonam. European Journal of Clinical Microbiology and Infectious Diseases 7, 780-2.
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