메뉴 건너뛰기




Volumn 66, Issue 1, 2006, Pages 1-14

Optimising dosing strategies of antibacterials utilising pharmacodynamic principles: Impact on the development of resistance

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; AZITHROMYCIN; BETA LACTAM; CARBAPENEM; CEFEPIME; CEFMENOXIME; CEPHALOSPORIN; CIPROFLOXACIN; CLARITHROMYCIN; CLINDAMYCIN; ERYTHROMYCIN; GARENOXACIN; GATIFLOXACIN; GENTAMICIN; GLYCOPEPTIDE; LEVOFLOXACIN; LINCOSAMIDE; LINEZOLID; MACROLIDE; METRONIDAZOLE; OXAZOLIDINONE DERIVATIVE; PENICILLIN G; PIPERACILLIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TAZOBACTAM; TELITHROMYCIN; TOBRAMYCIN; UNINDEXED DRUG; VANCOMYCIN;

EID: 31344476129     PISSN: 00126667     EISSN: 00126667     Source Type: Journal    
DOI: 10.2165/00003495-200666010-00001     Document Type: Review
Times cited : (90)

References (70)
  • 1
    • 0141673604 scopus 로고    scopus 로고
    • Antimicrobial resistance among gram-negative organisms in the intensive care unit
    • Clark NM, Patterson J, Lynch JP. Antimicrobial resistance among gram-negative organisms in the intensive care unit. Curr Opin Crit Care 2003; 9: 413-23
    • (2003) Curr Opin Crit Care , vol.9 , pp. 413-423
    • Clark, N.M.1    Patterson, J.2    Lynch, J.P.3
  • 3
    • 2142760947 scopus 로고    scopus 로고
    • Antimicrobial pharmacodynamics: Critical interac-tions of 'bug and drug'
    • Drusano GL. Antimicrobial pharmacodynamics: critical interac-tions of 'bug and drug'. Nat Rev Microbiol 2004; 2: 289-300
    • (2004) Nat Rev Microbiol , vol.2 , pp. 289-300
    • Drusano, G.L.1
  • 4
    • 4143140875 scopus 로고    scopus 로고
    • Molecular epidemiology of selected multidrug-resistant bacteria: A global report from the SENTRY Antimicrobial Surveillance Program
    • Deshpande LM, Fritsche TR, Jones RN. Molecular epidemiology of selected multidrug-resistant bacteria: a global report from the SENTRY Antimicrobial Surveillance Program. Diagn Microbiol Infect Dis 2004; 49: 231-6
    • (2004) Diagn Microbiol Infect Dis , vol.49 , pp. 231-236
    • Deshpande, L.M.1    Fritsche, T.R.2    Jones, R.N.3
  • 5
    • 0346753421 scopus 로고    scopus 로고
    • National Nosocomial Infections Surveillance (NNIS) system report, data summary from January 1992 through June 2003, issued August 2003
    • National Nosocomial Infections Surveillance (NNIS) system report, data summary from January 1992 through June 2003, issued August 2003. Am J Infect Control 2003; 31: 481-98
    • (2003) Am J Infect Control , vol.31 , pp. 481-498
  • 6
    • 0037447017 scopus 로고    scopus 로고
    • Factors associated with relative rates of antimicrobial resistance among Streptococcus pneumoniae in the United States: Results from the TRUST Surveillance Program (1998-2002)
    • Karlowsky JA, Thornsberry C, Jones ME, et al. Factors associated with relative rates of antimicrobial resistance among Streptococcus pneumoniae in the United States: results from the TRUST Surveillance Program (1998-2002). Clin Infect Dis 2003; 36: 963-70
    • (2003) Clin Infect Dis , vol.36 , pp. 963-970
    • Karlowsky, J.A.1    Thornsberry, C.2    Jones, M.E.3
  • 7
    • 0033595136 scopus 로고    scopus 로고
    • Decreased susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada: Canadian Bacterial Surveillance Network
    • Chen DK, McGeer A, de Azavedo JC, et al. Decreased susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada: Canadian Bacterial Surveillance Network. N Engl J Med 1999; 341: 233-9
    • (1999) N Engl J Med , vol.341 , pp. 233-239
    • Chen, D.K.1    McGeer, A.2    De Azavedo, J.C.3
  • 8
    • 0032908242 scopus 로고    scopus 로고
    • Emergence of fluoroquinolone resistance among multiply resistant strains of Streptococcus pneumoniae in Hong Kong
    • Ho PL, Que TL, Tsang DN, et al. Emergence of fluoroquinolone resistance among multiply resistant strains of Streptococcus pneumoniae in Hong Kong. Antimicrob Agents Chemother 1999; 43: 1310-3
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1310-1313
    • Ho, P.L.1    Que, T.L.2    Tsang, D.N.3
  • 9
    • 0042160273 scopus 로고    scopus 로고
    • Emergence of levofloxacin-resistant pneumococci in immunocompromised adults after therapy for community-acquired pneumonia
    • Anderson KB, Tan JS, File TM, et al. Emergence of levofloxacin-resistant pneumococci in immunocompromised adults after therapy for community-acquired pneumonia. Clin Infect Dis 2003; 37: 376-81
    • (2003) Clin Infect Dis , vol.37 , pp. 376-381
    • Anderson, K.B.1    Tan, J.S.2    File, T.M.3
  • 10
    • 0037035122 scopus 로고    scopus 로고
    • Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia
    • Davidson R, Cavalcanti R, Brunton JL, et al. Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. N Engl J Med 2002; 346: 747-50
    • (2002) N Engl J Med , vol.346 , pp. 747-750
    • Davidson, R.1    Cavalcanti, R.2    Brunton, J.L.3
  • 11
    • 5444226347 scopus 로고    scopus 로고
    • Occurrence and antimicrobial resistance pattern comparisons among bloodstream infection isolates from the SENTRY Antimicrobial Surveillance Program (1997-2002)
    • Biedenbach DJ, Moet GJ, Jones RN. Occurrence and antimicrobial resistance pattern comparisons among bloodstream infection isolates from the SENTRY Antimicrobial Surveillance Program (1997-2002). Diagn Microbiol Infect Dis 2004; 50: 59-69
    • (2004) Diagn Microbiol Infect Dis , vol.50 , pp. 59-69
    • Biedenbach, D.J.1    Moet, G.J.2    Jones, R.N.3
  • 12
    • 9644274002 scopus 로고    scopus 로고
    • National surveillance of antimicrobial resistance in Pseudomonas aeruginosa isolates obtained from intensive care unit patients from 1993 to 2002
    • Obritsch MD, Fish DN, MacLaren R, et al. National surveillance of antimicrobial resistance in Pseudomonas aeruginosa isolates obtained from intensive care unit patients from 1993 to 2002. Antimicrob Agents Chemother 2004; 48: 4606-10
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 4606-4610
    • Obritsch, M.D.1    Fish, D.N.2    MacLaren, R.3
  • 13
    • 0036498656 scopus 로고    scopus 로고
    • Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: Our worst nightmare?
    • Livermore DM. Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare? Clin Infect Dis 2002; 34: 634-40
    • (2002) Clin Infect Dis , vol.34 , pp. 634-640
    • Livermore, D.M.1
  • 14
    • 0037453976 scopus 로고    scopus 로고
    • Antibiotic resistance among gram-negative bacilli in US intensive care units: Implications for fluoroquinolone use
    • Neuhauser MM, Weinstein RA, Rydman R, et al. Antibiotic resistance among gram-negative bacilli in US intensive care units: implications for fluoroquinolone use. JAMA 2003; 289: 885-8
    • (2003) JAMA , vol.289 , pp. 885-888
    • Neuhauser, M.M.1    Weinstein, R.A.2    Rydman, R.3
  • 15
    • 0025938759 scopus 로고
    • Enterobacter bacteremia: Clinical features and emergence of antibiotic resistance during therapy
    • Chow JW, Fine MJ, Shlaes DM, et al. Enterobacter bacteremia: clinical features and emergence of antibiotic resistance during therapy. Ann Intern Med 1991; 115: 585-90
    • (1991) Ann Intern Med , vol.115 , pp. 585-590
    • Chow, J.W.1    Fine, M.J.2    Shlaes, D.M.3
  • 16
    • 0142146624 scopus 로고    scopus 로고
    • Pharmacodynamics of quinolones
    • Nightingale CH, Marakawa T, Ambrose PG, editors. New York: Marcel Dekker Inc.
    • Owens RC, Ambrose PG. Pharmacodynamics of quinolones. In: Nightingale CH, Marakawa T, Ambrose PG, editors. Antimi-crobial pharmacodynamics in theory and clinical practice. New York: Marcel Dekker Inc., 2002: 155-76
    • (2002) Antimicrobial Pharmacodynamics in Theory and Clinical Practice , pp. 155-176
    • Owens, R.C.1    Ambrose, P.G.2
  • 17
    • 0031952586 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic parameters: Rationale for antibacterial dosing of mice and men
    • Craig WA. Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis 1998; 26: 1-10
    • (1998) Clin Infect Dis , vol.26 , pp. 1-10
    • Craig, W.A.1
  • 18
    • 0022528827 scopus 로고
    • Correlation of pharmacokinetic indices with therapeutic outcome in patients receiving aminoglycosides
    • Deziel-Evans LM, Murphy JE, Job ML. Correlation of pharmacokinetic indices with therapeutic outcome in patients receiving aminoglycosides. Clin Pharm 1986; 5: 319-24
    • (1986) Clin Pharm , vol.5 , pp. 319-324
    • Deziel-Evans, L.M.1    Murphy, J.E.2    Job, M.L.3
  • 19
    • 0031807608 scopus 로고    scopus 로고
    • Dosing of aminoglycosides to rapidly attain pharmacodynamic goals and hasten therapeutic response by using individualized pharmacokinetic monitoring of patients with pneumonia caused by gram-negative organisms
    • Kashuba AD, Bertino JS, Nafziger AN. Dosing of aminoglycosides to rapidly attain pharmacodynamic goals and hasten therapeutic response by using individualized pharmacokinetic monitoring of patients with pneumonia caused by gram-negative organisms. Antimicrob Agents Chemother 1998; 42: 1842-4
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1842-1844
    • Kashuba, A.D.1    Bertino, J.S.2    Nafziger, A.N.3
  • 20
    • 0032979927 scopus 로고    scopus 로고
    • Optimizing aminoglycoside therapy for nosocomial pneumonia caused by gram-negative bacteria
    • Kashuba AD, Nafziger AN, Drusano GL, et al. Optimizing aminoglycoside therapy for nosocomial pneumonia caused by gram-negative bacteria. Antimicrob Agents Chemother 1999; 43: 623-9
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 623-629
    • Kashuba, A.D.1    Nafziger, A.N.2    Drusano, G.L.3
  • 21
    • 0028227018 scopus 로고
    • Once-daily gentamicin versus once-daily netilmicin in patients with serious infections: A randomized clinical trial
    • Prins JM, Buller HR, Kuijper EJ, et al. Once-daily gentamicin versus once-daily netilmicin in patients with serious infections: a randomized clinical trial. J Antimicrob Chemother 1994; 33: 823-35
    • (1994) J Antimicrob Chemother , vol.33 , pp. 823-835
    • Prins, J.M.1    Buller, H.R.2    Kuijper, E.J.3
  • 22
    • 0027518301 scopus 로고
    • Once versus thrice daily gentamicin in patients with serious infections
    • Prins JM, Buller HR, Kuijper EJ, et al. Once versus thrice daily gentamicin in patients with serious infections. Lancet 1993; 341: 335-9
    • (1993) Lancet , vol.341 , pp. 335-339
    • Prins, J.M.1    Buller, H.R.2    Kuijper, E.J.3
  • 23
    • 0027215734 scopus 로고
    • Once-daily versus thrice-daily dosing of netilmicin in combination with beta-lactam antibiotics as empirical therapy for febrile neutropenic patients
    • Rozdzinski E, Kern WV, Reichle A, et al. Once-daily versus thrice-daily dosing of netilmicin in combination with beta-lactam antibiotics as empirical therapy for febrile neutropenic patients. J Antimicrob Chemother 1993; 31: 585-98
    • (1993) J Antimicrob Chemother , vol.31 , pp. 585-598
    • Rozdzinski, E.1    Kern, W.V.2    Reichle, A.3
  • 24
    • 0025939694 scopus 로고
    • A prospective randomized study comparing once- versus twice-daily amikacin dosing in critically ill adult and paediatric patients
    • Marik PE, Lipman J, Kobilski S, et al. A prospective randomized study comparing once- versus twice-daily amikacin dosing in critically ill adult and paediatric patients. J Antimicrob Chemother 1991; 28: 753-64
    • (1991) J Antimicrob Chemother , vol.28 , pp. 753-764
    • Marik, P.E.1    Lipman, J.2    Kobilski, S.3
  • 25
    • 0029895354 scopus 로고    scopus 로고
    • Once-daily aminoglycoside dosing: Impact on requests and costs for therapeutic drug monitoring
    • Nicolau DP, Wu AH, Finocchiaro S, et al. Once-daily aminoglycoside dosing: impact on requests and costs for therapeutic drug monitoring. Ther Drug Monit 1996; 18: 263-6
    • (1996) Ther Drug Monit , vol.18 , pp. 263-266
    • Nicolau, D.P.1    Wu, A.H.2    Finocchiaro, S.3
  • 26
    • 0032515386 scopus 로고    scopus 로고
    • Pharmacodynamics of levofloxacin: A new paradigm for early clinical trials
    • Preston SL, Drusano GL, Berman AL, et al. Pharmacodynamics of levofloxacin: a new paradigm for early clinical trials. JAMA 1998; 279: 125-9
    • (1998) JAMA , vol.279 , pp. 125-129
    • Preston, S.L.1    Drusano, G.L.2    Berman, A.L.3
  • 27
    • 0027161344 scopus 로고
    • Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients
    • Forrest A, Nix DE, Ballow CH, et al. Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients. Antimicrob Agents Chemother 1993; 37: 1073-81
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 1073-1081
    • Forrest, A.1    Nix, D.E.2    Ballow, C.H.3
  • 28
    • 2442549489 scopus 로고    scopus 로고
    • Relationship between fluoroquinolone area under the curve: Minimum inhibitory concentration ratio and the probability of eradication of the infecting pathogen, in patients with nosocomial pneumonia
    • Drusano GL, Preston SL, Fowler C, et al. Relationship between fluoroquinolone area under the curve: minimum inhibitory concentration ratio and the probability of eradication of the infecting pathogen, in patients with nosocomial pneumonia. J Infect Dis 2004; 189: 1590-7
    • (2004) J Infect Dis , vol.189 , pp. 1590-1597
    • Drusano, G.L.1    Preston, S.L.2    Fowler, C.3
  • 29
    • 0034812780 scopus 로고    scopus 로고
    • Pharmacodynamics of fluoroquinolones against Streptococcus pneumoniae in patients with community-acquired respiratory tract infections
    • Ambrose PG, Grasela DM, Grasela TH, et al. Pharmacodynamics of fluoroquinolones against Streptococcus pneumoniae in patients with community-acquired respiratory tract infections. Antimicrob Agents Chemother 2001; 45: 2793-7
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 2793-2797
    • Ambrose, P.G.1    Grasela, D.M.2    Grasela, T.H.3
  • 30
    • 0037710404 scopus 로고    scopus 로고
    • Antimicrobial susceptibility breakpoints and first-step parC mutations in Streptococcus pneumoniae: Redefining fluoroquinolone resistance
    • Lim S, Bast D, McGeer A, et al. Antimicrobial susceptibility breakpoints and first-step parC mutations in Streptococcus pneumoniae: redefining fluoroquinolone resistance. Emerg Infect Dis 2003; 9: 833-7
    • (2003) Emerg Infect Dis , vol.9 , pp. 833-837
    • Lim, S.1    Bast, D.2    McGeer, A.3
  • 31
    • 0041767486 scopus 로고    scopus 로고
    • Activities of mutant prevention concentration-targeted moxifloxacin and levofloxacin against Streptococcus pneumoniae in an in vitro pharmacodynamic model
    • Allen GP, Kaatz GW, Rybak MJ. Activities of mutant prevention concentration-targeted moxifloxacin and levofloxacin against Streptococcus pneumoniae in an in vitro pharmacodynamic model. Antimicrob Agents Chemother 2003; 47: 2606-14
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 2606-2614
    • Allen, G.P.1    Kaatz, G.W.2    Rybak, M.J.3
  • 32
    • 4644244664 scopus 로고    scopus 로고
    • Mutant prevention concentrations for single-step fluoroquinolone- resistant mutants of wild-type, efflux-positive, or ParC or GyrA mutation-containing Streptococcus pneumoniae isolates
    • Smith HJ, Walters M, Hisanaga T, et al. Mutant prevention concentrations for single-step fluoroquinolone-resistant mutants of wild-type, efflux-positive, or ParC or GyrA mutation-containing Streptococcus pneumoniae isolates. Antimicrob Agents Chemother 2004; 48: 3954-8
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 3954-3958
    • Smith, H.J.1    Walters, M.2    Hisanaga, T.3
  • 33
    • 0037439449 scopus 로고    scopus 로고
    • Prevention of resistance: A goal for dose selection for antimicrobial agents
    • Drusano GL. Prevention of resistance: a goal for dose selection for antimicrobial agents. Clin Infect Dis 2003; 36: S42-50
    • (2003) Clin Infect Dis , vol.36
    • Drusano, G.L.1
  • 34
    • 0031856680 scopus 로고    scopus 로고
    • The pharmacodynamics of beta-lactams
    • Turnidge JD. The pharmacodynamics of beta-lactams. Clin Infect Dis 1998; 27: 10-22
    • (1998) Clin Infect Dis , vol.27 , pp. 10-22
    • Turnidge, J.D.1
  • 35
    • 0021708980 scopus 로고
    • Role for dual individualization with cefmenoxime
    • Schentag JJ, Smith IL, Swanson DJ, et al. Role for dual individualization with cefmenoxime. Am J Med 1984; 77: 43-50
    • (1984) Am J Med , vol.77 , pp. 43-50
    • Schentag, J.J.1    Smith, I.L.2    Swanson, D.J.3
  • 36
    • 0035136786 scopus 로고    scopus 로고
    • Evidence to support the rationale that bacterial eradication in respiratory tract infection is an important aim of antimicrobial therapy
    • Dagan R, Klugman KP, Craig WA, et al. Evidence to support the rationale that bacterial eradication in respiratory tract infection is an important aim of antimicrobial therapy. J Antimicrob Chemother 2001; 47: 129-40
    • (2001) J Antimicrob Chemother , vol.47 , pp. 129-140
    • Dagan, R.1    Klugman, K.P.2    Craig, W.A.3
  • 37
    • 0036736403 scopus 로고    scopus 로고
    • Pharmacodynamics of cefepime in patients with Gram-negative infections
    • Tam VH, McKinnon PS, Akins RL, et al. Pharmacodynamics of cefepime in patients with Gram-negative infections. J Antimicrob Chemother 2002; 50: 425-8
    • (2002) J Antimicrob Chemother , vol.50 , pp. 425-428
    • Tam, V.H.1    McKinnon, P.S.2    Akins, R.L.3
  • 38
    • 31344445291 scopus 로고    scopus 로고
    • Cefepime pharmacodynamics in patients with extended spectrum beta lactamases (ESBL) and non-ESBL infections
    • abstract no. A-1151. Dec 16-19; Washington, DC
    • Lee SY, Kuti JK, Nicolau DP. Cefepime pharmacodynamics in patients with extended spectrum beta lactamases (ESBL) and non-ESBL infections [abstract no. A-1151]. 45th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2005 Dec 16-19; Washington, DC
    • (2005) 45th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Lee, S.Y.1    Kuti, J.K.2    Nicolau, D.P.3
  • 39
    • 0035001026 scopus 로고    scopus 로고
    • Continuous versus intermittent administration of ceftazidime in intensive care unit patients with nosocomial pneumonia
    • Nicolau DP, McNabb J, Lacy MK, et al. Continuous versus intermittent administration of ceftazidime in intensive care unit patients with nosocomial pneumonia. Int J Antimicrob Agents 2001; 17: 497-504
    • (2001) Int J Antimicrob Agents , vol.17 , pp. 497-504
    • Nicolau, D.P.1    McNabb, J.2    Lacy, M.K.3
  • 40
    • 0036206559 scopus 로고    scopus 로고
    • Clinical efficacy and pharmacoeconomics of a continuous-infusion piperacillin-tazobactam program in a large community teaching hospital
    • Grant EM, Kuti JL, Nicolau DP, et al. Clinical efficacy and pharmacoeconomics of a continuous-infusion piperacillin-tazobactam program in a large community teaching hospital. Pharmacotherapy 2002; 22: 471-83
    • (2002) Pharmacotherapy , vol.22 , pp. 471-483
    • Grant, E.M.1    Kuti, J.L.2    Nicolau, D.P.3
  • 41
    • 0345130000 scopus 로고    scopus 로고
    • Continuous infusion versus intermittent administration of meropenem in critically ill patients
    • Thalhammer F, Traunmuller F, El Menyawi I, et al. Continuous infusion versus intermittent administration of meropenem in critically ill patients. J Antimicrob Chemother 1999; 43: 523-7
    • (1999) J Antimicrob Chemother , vol.43 , pp. 523-527
    • Thalhammer, F.1    Traunmuller, F.2    El Menyawi, I.3
  • 42
    • 18244391438 scopus 로고    scopus 로고
    • Evaluation by Monte Carlo simulation of the pharmacokinetics of two doses of meropenem administered intermittently or as a continuous infusion in healthy volunteers
    • Krueger WA, Bulitta J, Kinzig-Schippers M, et al. Evaluation by Monte Carlo simulation of the pharmacokinetics of two doses of meropenem administered intermittently or as a continuous infusion in healthy volunteers. Antimicrob Agents Chemother 2005; 49: 1881-9
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 1881-1889
    • Krueger, W.A.1    Bulitta, J.2    Kinzig-Schippers, M.3
  • 43
    • 0037373164 scopus 로고    scopus 로고
    • Integration of population pharmacokinetics, a pharmacodynamic target, and microbiologic surveillance data to generate a rational empiric dosing strategy for cefepime against Pseudomonas aeruginosa
    • Tam VH, Louie A, Lomaestro BM, et al. Integration of population pharmacokinetics, a pharmacodynamic target, and microbiologic surveillance data to generate a rational empiric dosing strategy for cefepime against Pseudomonas aeruginosa. Pharmacotherapy 2003; 23: 291-5
    • (2003) Pharmacotherapy , vol.23 , pp. 291-295
    • Tam, V.H.1    Louie, A.2    Lomaestro, B.M.3
  • 44
    • 0042743965 scopus 로고    scopus 로고
    • Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy
    • Jumbe N, Louie A, Leary R, et al. Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy. J Clin Invest 2003; 112: 275-85
    • (2003) J Clin Invest , vol.112 , pp. 275-285
    • Jumbe, N.1    Louie, A.2    Leary, R.3
  • 45
    • 22544468795 scopus 로고    scopus 로고
    • Bacterial-population responses to drug-selective pressure: Examination of garenoxacin's effect on Pseudomonas aeruginosa
    • Tam VH, Louie A, Deziel MR, et al. Bacterial-population responses to drug-selective pressure: examination of garenoxacin's effect on Pseudomonas aeruginosa. J Infect Dis 2005; 192: 420-8
    • (2005) J Infect Dis , vol.192 , pp. 420-428
    • Tam, V.H.1    Louie, A.2    Deziel, M.R.3
  • 46
    • 1642502330 scopus 로고    scopus 로고
    • Pharmacodynamics of moxifloxacin and levofloxacin at simulated epithelial lining fluid drug concentrations against Streptococcus pneumoniae
    • Florea NR, Tessier PR, Zhang C, et al. Pharmacodynamics of moxifloxacin and levofloxacin at simulated epithelial lining fluid drug concentrations against Streptococcus pneumoniae. Antimicrob Agents Chemother 2004; 48: 1215-21
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 1215-1221
    • Florea, N.R.1    Tessier, P.R.2    Zhang, C.3
  • 47
    • 33747879840 scopus 로고    scopus 로고
    • Evaluation of bacterial kill when modeling the bronchopulomonary pharmacokinetic profile of moxifloxacin (MOX) and levofloxacin (LVX) against parC containing isolates of Streptococcus pneumoniae (SPN)
    • abstract no. A-453. Dec 16-19; Washington, DC
    • DeRyke CA, Du X, Nicolau DP. Evaluation of bacterial kill when modeling the bronchopulomonary pharmacokinetic profile of moxifloxacin (MOX) and levofloxacin (LVX) against parC containing isolates of Streptococcus pneumoniae (SPN) [abstract no. A-453]. 45th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2005 Dec 16-19; Washington, DC
    • (2005) 45th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • DeRyke, C.A.1    Du, X.2    Nicolau, D.P.3
  • 49
    • 0031940776 scopus 로고    scopus 로고
    • Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapy
    • Thomas JK, Forrest A, Bhavnani SM, et al. Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapy. Antimicrob Agents Chemother 1998; 42: 521-7
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 521-527
    • Thomas, J.K.1    Forrest, A.2    Bhavnani, S.M.3
  • 50
    • 0037633871 scopus 로고    scopus 로고
    • Stretching the mutant prevention concentration (MPC) beyond its limits
    • Smith HJ, Nichol KA, Hoban DJ, et al. Stretching the mutant prevention concentration (MPC) beyond its limits. J Antimicrob Chemother 2003; 51: 1323-5
    • (2003) J Antimicrob Chemother , vol.51 , pp. 1323-1325
    • Smith, H.J.1    Nichol, K.A.2    Hoban, D.J.3
  • 51
    • 0035139520 scopus 로고    scopus 로고
    • Mutant prevention concentrations of fluoroquinolones for clinical isolates of Streptococcus pneumoniae
    • Blondeau JM, Zhao X, Hansen G, et al. Mutant prevention concentrations of fluoroquinolones for clinical isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother 2001; 45: 433-8
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 433-438
    • Blondeau, J.M.1    Zhao, X.2    Hansen, G.3
  • 52
    • 0038639673 scopus 로고    scopus 로고
    • The mutant selection window and antimicrobial resistance
    • Drlica K. The mutant selection window and antimicrobial resistance. J Antimicrob Chemother 2003; 52: 11-7
    • (2003) J Antimicrob Chemother , vol.52 , pp. 11-17
    • Drlica, K.1
  • 53
    • 3843150553 scopus 로고    scopus 로고
    • The role of PK/PD parameters to avoid selection and increase of resistance: Mutant prevention concentration
    • Blondeau JM, Hansen G, Metzler K, et al. The role of PK/PD parameters to avoid selection and increase of resistance: mutant prevention concentration. J Chemother 2004; 16 Suppl. 3: 1-19
    • (2004) J Chemother , vol.16 , Issue.3 SUPPL. , pp. 1-19
    • Blondeau, J.M.1    Hansen, G.2    Metzler, K.3
  • 54
    • 0032481410 scopus 로고    scopus 로고
    • Low dosage and long treatment duration of beta-lactam: Risk factors for carriage of penicillin-resistant Streptococcus pneumoniae
    • Guillemot D, Carbon C, Balkau B, et al. Low dosage and long treatment duration of beta-lactam: risk factors for carriage of penicillin-resistant Streptococcus pneumoniae. JAMA 1998; 279: 365-70
    • (1998) JAMA , vol.279 , pp. 365-370
    • Guillemot, D.1    Carbon, C.2    Balkau, B.3
  • 55
    • 0037311178 scopus 로고    scopus 로고
    • Suboptimal antibiotic dosage as a risk factor for selection of penicillin-resistant Streptococcus pneumoniae: In vitro kinetic model
    • Odenholt I, Gustafsson I, Lowdin E, et al. Suboptimal antibiotic dosage as a risk factor for selection of penicillin-resistant Streptococcus pneumoniae: in vitro kinetic model. Antimicrob Agents Chemother 2003; 47: 518-23
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 518-523
    • Odenholt, I.1    Gustafsson, I.2    Lowdin, E.3
  • 56
    • 0041767539 scopus 로고    scopus 로고
    • Selection of resistant Streptococcus pneumoniae during penicillin treatment in vitro and in three animal models
    • Knudsen JD, Odenholt I, Erlendsdottir H, et al. Selection of resistant Streptococcus pneumoniae during penicillin treatment in vitro and in three animal models. Antimicrob Agents Chemother 2003; 47: 2499-506
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 2499-2506
    • Knudsen, J.D.1    Odenholt, I.2    Erlendsdottir, H.3
  • 57
    • 31344451986 scopus 로고    scopus 로고
    • In vivo pharmacodynamic characterization of meropenem and its impact on the selection of resistance among Pseudomonas aeruginosa
    • Nov 2-5; Atlanta (GA)
    • Ong CT, Tessier PR, Li C, et al. In vivo pharmacodynamic characterization of meropenem and its impact on the selection of resistance among Pseudomonas aeruginosa [abstract]. American College of Clinical Pharmacy Annual Meeting; 2003 Nov 2-5; Atlanta (GA)
    • (2003) American College of Clinical Pharmacy Annual Meeting
    • Ong, C.T.1    Tessier, P.R.2    Li, C.3
  • 58
    • 31344458862 scopus 로고    scopus 로고
    • Efflux pumps do not translate to in vivo failure in efficacy or emergence of resistance to meropenem, imipenem, or cefepime
    • abstract no. A-1867. Oct 30-Nov 2; Washington, DC
    • Ong CT, Tessier PR, Li C, et al. Efflux pumps do not translate to in vivo failure in efficacy or emergence of resistance to meropenem, imipenem, or cefepime [abstract no. A-1867]. 44th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2004 Oct 30-Nov 2; Washington, DC
    • (2004) 44th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Ong, C.T.1    Tessier, P.R.2    Li, C.3
  • 59
    • 20444440421 scopus 로고    scopus 로고
    • Comparison of betalactams in counter-selecting resistance of Pseudomonas aeruginosa
    • Tam VH, Schilling AN, Melnick DA, et al. Comparison of betalactams in counter-selecting resistance of Pseudomonas aeruginosa. Diagn Microbiol Infect Dis 2005; 52: 145-51
    • (2005) Diagn Microbiol Infect Dis , vol.52 , pp. 145-151
    • Tam, V.H.1    Schilling, A.N.2    Melnick, D.A.3
  • 60
    • 19644387088 scopus 로고    scopus 로고
    • Questioning the paradigm: Monotherapy vs combination antimicrobial thearpy for treatment of Pseudomonas aeruginosa
    • DeRyke CA, Kuti JK, Nicolau DP. Questioning the paradigm: monotherapy vs combination antimicrobial thearpy for treatment of Pseudomonas aeruginosa. Conn Med 2005; 69: 271-5
    • (2005) Conn Med , vol.69 , pp. 271-275
    • DeRyke, C.A.1    Kuti, J.K.2    Nicolau, D.P.3
  • 61
    • 21844464306 scopus 로고    scopus 로고
    • Effect of aminoglycoside and beta-lactam combination therapy versus betalactam monotherapy on the emergence of antimicrobial resistance: A meta-analysis of randomized, controlled trials
    • Bliziotis IA, Samonis G, Vardakas KZ, et al. Effect of aminoglycoside and beta-lactam combination therapy versus betalactam monotherapy on the emergence of antimicrobial resistance: a meta-analysis of randomized, controlled trials. Clin Infect Dis 2005; 41: 149-58
    • (2005) Clin Infect Dis , vol.41 , pp. 149-158
    • Bliziotis, I.A.1    Samonis, G.2    Vardakas, K.Z.3
  • 62
    • 0033059706 scopus 로고    scopus 로고
    • Emergence of antibiotic-resistant Pseudomonas aeruginosa: Comparison of risks associated with different antipseudomonal agents
    • Carmeli Y, Troillet N, Eliopoulos GM, et al. Emergence of antibiotic-resistant Pseudomonas aeruginosa: comparison of risks associated with different antipseudomonal agents. Antimicrob Agents Chemother 1999; 43: 1379-82
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1379-1382
    • Carmeli, Y.1    Troillet, N.2    Eliopoulos, G.M.3
  • 63
    • 0035577355 scopus 로고    scopus 로고
    • Influence of previous exposure to antibiotic therapy on the susceptibility pattern of Pseudomonas aeruginosa bacteremic isolates
    • El Amari EB, Chamot E, Auckenthaler R, et al. Influence of previous exposure to antibiotic therapy on the susceptibility pattern of Pseudomonas aeruginosa bacteremic isolates. Clin Infect Dis 2001; 33: 1859-64
    • (2001) Clin Infect Dis , vol.33 , pp. 1859-1864
    • El Amari, E.B.1    Chamot, E.2    Auckenthaler, R.3
  • 64
    • 0037563090 scopus 로고    scopus 로고
    • Beta lactam monotherapy versus beta lactam-aminoglycoside combination therapy for fever with neutropenia: Systematic review and meta-analysis
    • Paul M, Soares-Weiser K, Leibovici L. Beta lactam monotherapy versus beta lactam-aminoglycoside combination therapy for fever with neutropenia: systematic review and meta-analysis. BMJ 2003; 326: 1111
    • (2003) BMJ , vol.326 , pp. 1111
    • Paul, M.1    Soares-Weiser, K.2    Leibovici, L.3
  • 65
    • 0141556333 scopus 로고    scopus 로고
    • Prevention of the emergence of resistance in Pseudomonas aeruginosa infections through pharmacodynamic dosing and combination chemotherapy
    • May 17-22; Atlanta (GA)
    • Drusano G, Louie A, Miller MH, et al. Prevention of the emergence of resistance in Pseudomonas aeruginosa infections through pharmacodynamic dosing and combination chemotherapy [abstract]. 98th International Conference of the American Thoracic Society; 2002 May 17-22; Atlanta (GA)
    • (2002) 98th International Conference of the American Thoracic Society
    • Drusano, G.1    Louie, A.2    Miller, M.H.3
  • 66
    • 16244367470 scopus 로고    scopus 로고
    • In vitro synergy and selection of resistance by fluoroquinolones plus amikacin or beta-lactams against extended-spectrum beta-lactamase-producing Escherichia coli
    • Drago L, De Vecchi E, Nicola L, et al. In vitro synergy and selection of resistance by fluoroquinolones plus amikacin or beta-lactams against extended-spectrum beta-lactamase-producing Escherichia coli. J Chemother 2005; 17: 46-53
    • (2005) J Chemother , vol.17 , pp. 46-53
    • Drago, L.1    De Vecchi, E.2    Nicola, L.3
  • 67
    • 0020412098 scopus 로고
    • Selection of aminoglycoside-resistant variants of Pseudomonas aeruginosa in an in vivo model
    • Gerber AU, Vastola AP, Brandel J, et al. Selection of aminoglycoside-resistant variants of Pseudomonas aeruginosa in an in vivo model. J Infect Dis 1982; 146: 691-7
    • (1982) J Infect Dis , vol.146 , pp. 691-697
    • Gerber, A.U.1    Vastola, A.P.2    Brandel, J.3
  • 68
    • 28844443170 scopus 로고    scopus 로고
    • Optimization of meropenem minimum concentration/MIC ratio to suppress in vitro resistance of Pseudomonas aeruginosa
    • Tam VH, Schilling AN, Neshat S, et al. Optimization of meropenem minimum concentration/MIC ratio to suppress in vitro resistance of Pseudomonas aeruginosa. Antimicrob Agents Chemother 2005; 49: 4920-7
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 4920-4927
    • Tam, V.H.1    Schilling, A.N.2    Neshat, S.3
  • 69
    • 0037237618 scopus 로고    scopus 로고
    • The mutant prevention concentration (MPC): A review
    • Allen GP. The mutant prevention concentration (MPC): a review. J Infect Dis Pharmacother 2003; 6: 27-47
    • (2003) J Infect Dis Pharmacother , vol.6 , pp. 27-47
    • Allen, G.P.1
  • 70
    • 0022219276 scopus 로고
    • Pseudomonas bacteremia: Retrospective analysis of 410 episodes
    • Bodey GP, Jadeja L, Elting L. Pseudomonas bacteremia: retrospective analysis of 410 episodes. Arch Intern Med 1985; 145: 1621-9
    • (1985) Arch Intern Med , vol.145 , pp. 1621-1629
    • Bodey, G.P.1    Jadeja, L.2    Elting, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.