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Volumn 4, Issue 2, 2005, Pages 88-90

Visualizing drug efficacy in vivo

Author keywords

Cytochrome P 450 enzymes; Drug efficacy; Imaging; In vivo; Luciferase reporter; Transgenic mice

Indexed keywords

BIOASSAY; ENZYMES; MEDICAL IMAGING; METABOLISM; PHARMACOKINETICS; PHYSIOLOGICAL MODELS;

EID: 31344475955     PISSN: 15353508     EISSN: None     Source Type: Journal    
DOI: 10.1162/15353500200505109     Document Type: Article
Times cited : (5)

References (13)
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    • Ansede JH, Thakker DR (2004). High-throughput screening for stability and inhibitory activity of compounds toward cytochrome P450-mediated metabolism. J Pharm Sci. 93:239-255.
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    • Ansede, J.H.1    Thakker, D.R.2
  • 2
    • 31344449488 scopus 로고    scopus 로고
    • Luminescent assays for recombinant and liver microsome cytochrome P450 activities
    • Call JJ, Ho S, Ma D, Simpson D (2003). Luminescent assays for recombinant and liver microsome cytochrome P450 activities. Drug Metab Rev. 35:28.
    • (2003) Drug Metab Rev , vol.35 , pp. 28
    • Call, J.J.1    Ho, S.2    Ma, D.3    Simpson, D.4
  • 5
    • 4544232468 scopus 로고    scopus 로고
    • Inhibitors of dipeptidyl peptidase IV: A novel approach for the prevention and treatment of Type 2 diabetes?
    • Deacon CF, Ahren B, Hoist JJ (2004). Inhibitors of dipeptidyl peptidase IV: A novel approach for the prevention and treatment of Type 2 diabetes? Expert Opin Investig Drugs. 13:1091-1102.
    • (2004) Expert Opin Investig Drugs , vol.13 , pp. 1091-1102
    • Deacon, C.F.1    Ahren, B.2    Hoist, J.J.3
  • 9
    • 0023897416 scopus 로고
    • A new type of ultrasensitive bioluminogenic enzyme substrates: I. Enzyme substrates with D-luciferin as leaving group
    • Miska W, Geiger R (1988). A new type of ultrasensitive bioluminogenic enzyme substrates: I. Enzyme substrates with D-luciferin as leaving group. Biol Chem Hoppe Seyler. 369: 407-411.
    • (1988) Biol Chem Hoppe Seyler , vol.369 , pp. 407-411
    • Miska, W.1    Geiger, R.2
  • 11
    • 23244464739 scopus 로고    scopus 로고
    • Thymidylate synthase: A critical target in cancer therapy?
    • Rustum YM (2004). Thymidylate synthase: A critical target in cancer therapy? Front Biosci. 9:2467-2473.
    • (2004) Front Biosci , vol.9 , pp. 2467-2473
    • Rustum, Y.M.1
  • 12
    • 0031569864 scopus 로고    scopus 로고
    • Mouse cytochrome P450 (Cyp3a11): Predominant expression in liver and capacity to activate aflatoxin B1
    • Yanagimoto T, Itoh S, Sawada M, Kamataki T (1997). Mouse cytochrome P450 (Cyp3a11): Predominant expression in liver and capacity to activate aflatoxin B1. Arch Biochem Biopbys. 340:215-218.
    • (1997) Arch Biochem Biopbys , vol.340 , pp. 215-218
    • Yanagimoto, T.1    Itoh, S.2    Sawada, M.3    Kamataki, T.4
  • 13
    • 8444237774 scopus 로고    scopus 로고
    • A Cyp la2-luciferase transgenic CD-1 mouse model: Responses to aryl hydrocarbons similar to the humanized AhR mice
    • Zhang W, Moorthy B, Chen M, Muthiah K, Coffee R, Purchio AF, West DB (2004). A Cyp la2-luciferase transgenic CD-1 mouse model: Responses to aryl hydrocarbons similar to the humanized AhR mice. Toxicol Sci. 82:297-307.
    • (2004) Toxicol Sci , vol.82 , pp. 297-307
    • Zhang, W.1    Moorthy, B.2    Chen, M.3    Muthiah, K.4    Coffee, R.5    Purchio, A.F.6    West, D.B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.