An epidemiologically significant epitope of a 1998 human influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex

Journal of Molecular Biology

Volumn 356, Issue 3, 2006, Pages 651-663

  Venkatramani, Lalitha ^a   Bochkareva, Elena ^a,b   Lee, Janis T ^a   Gulati, Upma ^a   Graeme Laver, W ^a,c   Bochkarev, Alexey ^a,b   Air, Gillian M ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c NONE   (Australia)

Author keywords

Antigenic drift; Influenza virus; Neuraminidase Fab structure; Water mediated hydrogen bonds

Indexed keywords

EPITOPE; HEMAGGLUTININ; IMMUNOGLOBULIN F(AB) FRAGMENT; INFLUENZA VACCINE; MONOCLONAL ANTIBODY; PROTEIN MEM5; SIALIDASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANTIGEN ANTIBODY REACTION; ARTICLE; CRYSTAL STRUCTURE; HYDRATION; HYDROGEN BOND; INFLUENZA VIRUS; MUTATION; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; VIRUS MUTATION;

HUMAN INFLUENZA VIRUS; ORTHOMYXOVIRIDAE;

EID: 31344475098     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.11.061     Document Type: Article

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