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Volumn 16, Issue 5, 2006, Pages 1440-1444

Erratum: Hetaryl imidazoles: Novel dual inhibitors of VEGF receptors I and II (Bioorganic and Medicinal Chemistry Letters (2006) 16 (1440-1444) DOI: 10.1016/j.bmcl.2005.11.033);Hetaryl imidazoles: A novel dual inhibitors of VEGF receptors I and II

Author keywords

4 (Azolylethyl)thiazole 5 carboxamides; Angiogenesis; Dual kinase inhibitor; Receptor tyrosine kinase; Vascular endothelial growth factor receptor 2

Indexed keywords

IMIDAZOLE DERIVATIVE; PROTEIN TYROSINE KINASE; VANDETANIB; VASCULOTROPIN INHIBITOR; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; VATALANIB;

EID: 31344474265     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.01.119     Document Type: Erratum
Times cited : (26)

References (21)
  • 2
    • 0030952289 scopus 로고    scopus 로고
    • W. Risau Nature 386 1997 671
    • (1997) Nature , vol.386 , pp. 671
    • Risau, W.1
  • 3
    • 15344340324 scopus 로고    scopus 로고
    • TM (Bevacizumab) has recently been approved to treat colorectal cancer, see C. Culy Drugs Today 41 2005 23
    • (2005) Drugs Today , vol.41 , pp. 23
    • Culy, C.1
  • 13
    • 31344478871 scopus 로고    scopus 로고
    • note
    • 3: C, 56.54; H, 4.03; N, 19.78. Found: C, 56.31; H, 3.88, N, 19.56.
  • 14
    • 31344478083 scopus 로고    scopus 로고
    • note
    • 2, 2 mM DTT, and 1 mg/ml BSA) containing 0.5 mmol pGAT-biotin and 3-4 ng KDR enzyme was added to each well. After 5-10 min preincubation, the kinase reaction was initiated by the addition of 10 μl of 10 μM ATP in the reaction buffer, after which the plate was incubated at room temperature for 45 min. The reaction was stopped by addition of 50 μl KF buffer (50 mM Hepes, pH 7.5, 0.5 M KF, and 1 mg/ml BSA) containing 100 mM EDTA and 0.36 μg/ml PY20K (Eu-cryptate labeled anti-phosphotyrosine antibody, CIS Bio International) was added and after an additional 2 h incubation at rt, the plate was analyzed in a RUBYstar HTRF Reader.
  • 21
    • 31344464232 scopus 로고    scopus 로고
    • note
    • 4, and absorbance was measured at 450 nm.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.