Expression of human BMP-2 gene in different tissues of tobacco plants

Acta Genetica Sinica

Volumn 33, Issue 1, 2006, Pages 56-62

  Gao, Yuan ^a,b   Suo, Guang Li ^a   Han, Jin ^a   He, Zheng Quan ^b   Yao, Wei ^b   Dai, Jian Wu ^a  

^a INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^b CHINA THREE GORGES UNIVERSITY   (China)

Author keywords

Bone morphogenetic protein 2 (BMP 2); gus gene; Protein expression; Transgenic tobacco plant

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; HYBRID PROTEIN; RECOMBINANT PROTEIN;

ARTICLE; BIOREACTOR; BMP 2 GENE; BONE DEVELOPMENT; GENE; GENE EXPRESSION; GUS GENE; NONHUMAN; PLANT BIOTECHNOLOGY; PLANT LEAF; PLANT ROOT; PLANT STEM; PLANT TISSUE; PROTEIN CONTENT; PROTEIN EXPRESSION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE ENGINEERING; TOBACCO; TRANSGENIC PLANT;

NICOTIANA OBTUSIFOLIA; NICOTIANA TABACUM;

EID: 31344446389     PISSN: 03794172     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0379-4172(06)60009-7     Document Type: Article

References (15)

1. Urist M R, Behnam K, Kerendi F, Bagga D, Adkisson H D, Nevenzel J, Malinin T. Neutral lipids facilitate transfer of bone morphogenetic proteins and other noncollagenous proteins. Med Hypotheses, 1997, 49: 465-475.
2. Yasko A W, Lane J M, Fellinger E J, Rosen V, Wozney J M, Wang E A. The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2), a radiographic, histological, and biomechanical study in rats. J Bone Joint Surg Am, 1992, 74: 659-670.
3. Ruppert R, Hoffmann E, Sebald W. Human bone morphogenetic protein-2 contains a heparin-binding site which modifies its biological activity. Eur J Biochem, 1996, 237: 295-302.
4. Wozney J M, Rosen V, Celeste A J, Mitsock L M, Whitters M J, Kriz R, Hewick R, Wang E A. Novel regulators of bone formation: Molecular clones and activities. Science, 1988, 242: 1528-1534.
5. Hammonds R G, Jr Schwall R, Dudley A, Berkemeier L, Lai C, Lee J, Cunningham N, Reddi A H, Wood W I, Mason A J. Bone-inducing activity of mature BMP-2b produced from a hybrid BMP-2a/2b precursor. Mol Endocrinol, 1991, 5: 149-155.
6. Ishida N, Tsujimoto M, Kanaya T, Shimamura A, Tsuruoka N, Kodama S, Katayama T, Oikawa S, Matsui M, Nakanishi T, Kobayashi J, Nakazato H. Expression and characterization of human bone morphogenetic protein-2 in silkworm larvae infected with recombinant Bombyx mori nuclear polyhedrosis virus. J Biochem, 1994, 115: 279-285.
7. Ma J K, Drake P M, Christou P. The production of recombinant pharmaceutical proteins in plants. Na Rev Genet, 2003, 4: 794-805.
8. Daniell H, Lee S B, Panchal T, Wiebe P O. Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts. J Mol Biol, 2001, 311: 1001-1009.
9. Joshi C P, Zhou H, Huang X, Chiang V L. Context sequences of translation initiation codon in plants. Plant Mol Biol, 1997, 35: 993-1001.
10. Horsch R B, Fry J E, Hoffmann N L, Eichholtz D, Rogers S G, Fraley R T. A simple and general method for transferring genes into plants. Science, 1985, 227: 1229-1231.
11. Lige B, Ma S, van Huystee R B. Cationic peanut peroxidase: expression and characterization in transgenic tobacco and purification of the histidine-tagged protein. Plant Science, 1998, 136: 159-168.
12. Edwards K, Johnstone C, Thompson C. A simple and rapid method for the preparation of plant genomic DNA for PCR analysis. Nucleic Acids Res, 1991, 19: 1349.
13. Schenone A, Nobbio L, Mandich P, Bellone E, Abbruzzese M, Aymar F, Mancardi G L, Windebank A J. Underexpression of messenger RNA for peripheral myelin protein 22 in hereditary neuropathy with liability to pressure palsies. Neurology, 1997, 48 (2): 445-449.
14. Jefferson R A, Kavanagh T A, Bevan M W. GUS fusions: beta-glucuronidase as a sensitive and versatile gene fusion marker in higher plants. EMBO J, 1987, 6: 3901-3907.
15. Jefferson R A, Burgess S M, Hirsh D. beta-Glucuronidase from Escherichia coli as a gene-fusion marker. Proc Natl Acad Sci USA, 1986, 83: 8447-8451.