Compatibility and stability of the novel anticancer agent ES-285 · HCl formulated with 2-hydroxypropyl-β-cyclodextrin in infusion devices

Pharmazie

Volumn 61, Issue 1, 2006, Pages 21-24

  Den Brok, Monique W J ^a   Nuijen, B ^a   Garcia J L ^b   Miranda, E ^b   Calvo, P ^b   Manada, C ^b   Beijnen, J H ^a,c  

^a SLOTERVAART HOSPITAL   (Netherlands)

^b PHARMAMAR S A   (Spain)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ANTINEOPLASTIC AGENT; ES 285; GLUCOSE; NATURAL PRODUCT; POLYETHYLENE; SILICONE; SPISULOSINE; UNCLASSIFIED DRUG; WATER;

ARTICLE; CLAM; CONTAINER; DILUTION; DRUG FORMULATION; DRUG ISOLATION; DRUG STABILITY; FREEZE DRYING; INFUSION SYSTEM; LYOPHILISATE; SPISULA POLYNYMA; TUBE;

ALKANES; ANTINEOPLASTIC AGENTS; AREA UNDER CURVE; BETA-CYCLODEXTRINS; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; INFUSIONS, INTRAVENOUS; LIPIDS; SOLUBILITY; SOLUTIONS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 31144471516     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Center for Devices and Radiological Health of the US Food and Drug Administration (2001) Safety assessment of Di(2-ethylhexyl)phthalate (DEHP) released from PVC medical devices. http://www.fda.gov/cdrh/ost/dehp-pvc.pdf.
2. Chrzanowska-Wodnicka M, Burridge K (1996) Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J Cell Biol 133: 1403-1415.
3. Cuadros R, Montejo dG, Wandosell F, Faircloth G, Fernandez-Sousa JM, Avila J (2000) The marine compound spisulosine, an inhibitor of cell proliferation, promotes the disassembly of actin stress fibers. Cancer Lett 152: 23-29.
4. den Brok MWJ, Miranda E, Floriane P, Munt S, Manzanares I, Beijnen JH (2003) Development and validation of a liquid chromatography-ultraviolet absorbance detection assay using derivatisation for the novel marine anticancer agent ES-285 · HCl [(2S,3R)-2-amino-3-octadecanol hydrochloride] and its pharmaceutical dosage form. J Chromatogr A 1020: 251-258.
5. den Brok MWJ, School SC, Nuijen B, Hillebrand MJ, Beijnen JH (2004) 2-Hydroxypropyl-beta-cyclodextrin extracts 2-phenylphenol from silicone tubing. Int J Pharm 278: 303-309.
6. Higuchi T, Connors KA (1965) Phase-solubility techniques. Adv Anal Chem Instr 7: 117-212.
7. Jenke DR (2001) Evaluation of model solvent systems for assessing the accumulation of container extractables in drug formulations. Int J Pharm 224: 51-60.
8. Jimeno JM, Garcia-Gravalos D, Avila J, Smith B, Grant W, Faircloth GT (1999) ES-285, a marine natural product with activity against solid tumors. Proceedings of the American Association for Cancer Research In Clin Canc Res 5: 3792s.
9. Loftsson T, Masson M, Sigurjonsdottir JF (1999) Methods to enhance the complexation efficiency of cyclodextrins. S T P Pharma Sci 9: 237-242.
10. Nuijen B, Bouma M, Manada C, Jimeno JM, Lazaro LL, Bult A, Beijnen JH (2001) Compatibility and stability of the investigational polypeptide marine anticancer agent kahalalide F in infusion devices. Invest New Drugs 19: 273-281.
11. Pearson SD, Trissel LA (1993) Leaching of diethylhexyl phthalate from polyvinyl chloride containers by selected drugs and formulation components. Am J Hosp Pharm 50: 1405-1409.