Highly optimised global organisation of metabolic networks

IEE Proceedings Systems Biology

Volumn 152, Issue 4, 2005, Pages 179-184

  Tanaka, Reiko ^a   Csete, M ^b   Doyle, J ^c  

^a RIKEN   (Japan)

^b EMORY UNIVERSITY   (United States)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Bacterial metabolic networks; Biochemistry; Disease therapy; Diseases; Energy conservation; Enzymes; Fragility; Global structure; Highly optimised global organisation; Microorganisms; Molecular biophysics; Physiological models; Redox; Robustness; Stoichiometry

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; DISEASES; ENZYMES; METABOLISM; STOICHIOMETRY;

GLYCOLYSIS; METABOLIC NETWORKS;

BACTERIA;

AMINO ACID; FATTY ACID; NUCLEOTIDE;

ARTICLE; BACTERIAL METABOLISM; BIOCHEMISTRY; BIOLOGICAL MODEL; CATABOLISM; ENERGY CONSERVATION; ENZYME MECHANISM; HELICOBACTER PYLORI; METABOLITE; NONHUMAN; OXIDATION REDUCTION REACTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; STOICHIOMETRY;

ANIMALS; CELL PHYSIOLOGY; HUMANS; METABOLISM; MODELS, BIOLOGICAL; PROTEOME; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY;

BACTERIA (MICROORGANISMS); HELICOBACTER PYLORI;

EID: 31144452939     PISSN: 17412471     EISSN: None     Source Type: Journal    
DOI: 10.1049/ip-syb:20050042     Document Type: Article

References (11)

1. Papin, J.A., Stelling, J., Price, N.D., Klamt, S., Schuster, S. and Palsson, B.O.: 'Comparison of network-based pathway analysis methods', Trends Biotechnol., 2004, 22, p. 400-405
2. Berg, J.M., Tymoczko, J.L., and Stryer, L.: 'Biochemistry', (W. H. Freeman and Company, NY)2002
3. Carlson, J.M., and Doyle, J.C.: 'Complexity and robustness', Proc. Natl. Acad. Sci. USA, 2002, 99, (Suppl. 1), p. 2538-2545 0027-8424
4. Csete, M., and Doyle, J.: 'Bowties, metabolism, and disease', Trends Biotechnol., 2004, 22, p. 446-450
5. Tanaka, R.: 'Scale-rich metabolic networks', Phys. Rev. Lett., 2005 94, p. 168101 10.1103/PhysRevLett.94.168101 0031-9007
6. Barabàsi, A.-L., and Oltvai, Z.N.: 'Network biology: understanding the cell's functional organisation', Nat. Rev. Genet., 2004, 5, p. 101-113
7. Ma, H., and Zeng, A.-P.: 'The connectivity structure, giant strong component and centrality of metabolic networks', Bioinformatics, 2003 19, p. 1423-1430
8. Tanaka, R., Yi, T.-M., and Doyle, J.: 'Some protein interaction data do not exhibit power law statistics', FEBS Lett., 2005, 579, p. 5140-5144
9. Mandelbrot, B.B.: 'Fractals and scaling in finance: Discontinuity, concentration, risk', (Springer-Verlag, NY 1997)
10. Willinger, W., Alderson, D., Doyle, J., and Li, L.: 'More 'normal' than normal: Scaling distributions and complex systems' Proc. 2004 Winter Simulation Conf., 2004
11. Mahadevan, R., and Palsson, B.O.: 'Properties of metabolic networks: Structure versus function', Biophys. J.: Biophys. Lett., 2005, 88, p. L07-L09