Properties of metabolic networks: Structure versus function

Biophysical Journal

Volumn 88, Issue 1, 2005, Pages

  Mahadevan, R ^a,b   Palsson, B O ^b  

^a GENOMATICA INC   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN;

ARTICLE; BIOLOGICAL MODEL; BIOLOGICAL NETWORK; COMPUTER MODEL; ESCHERICHIA COLI; GENE; GENOME; GENOME SCALE BIOCHEMICAL NETWORK; GENOME SCALE METABOLIC NETWORK; GEOBACTER SULFURREDUCENS; METABOLISM; METABOLITE; MICROBIAL METABOLISM; NONHUMAN; PHENOTYPE; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; REACTION ANALYSIS; SACCHAROMYCES CEREVISIAE; SPECIES DIFFERENCE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ESCHERICHIA COLI; GEOBACTER SULFURREDUCENS; SACCHAROMYCES CEREVISIAE;

EID: 11244333081     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.104.055723     Document Type: Article

References (10)

1. Barabasi, A. L., and Z. N. Oltvai. 2004. Network biology: understanding the cell's functional organization. Nat. Rev. Genet. 5: 101-113.
2. Jeong, H., S. P. Mason, A. L. Barabasi, and Z. N. Oltvai. 2001. Lethality and centrality in protein networks. Nature. 411:41-42.
3. Arita, M. 2004. The metabolic world of Escherichia coli is not small. Proc. Natl. Acad. Sci. USA. 101:1543-1547.
4. Kauffman, K. J., P. Prakash, and J. S. Edwards. 2003. Advances in flux balance analysis. Curr. Opin. Biotechnol. 14:491-496.
5. Duarte, N. C., M. J. Herrgard, and B. Palsson. Reconstruction and validation of Saccharomyces cerevisiae iND750, a fully compartmentalized genome-scale metabolic model. 2004. Genome Res. 14:1298-1309.
6. Covert, M. W., E. M. Knight, J. L. Reed, M. J. Herrgard, and B. O. Palsson. Integrating high-throughput and computational data elucidates bacterial networks. 2004. Nature. 429:92-96.
7. Edwards, J. S., R. U. Ibarra, and B. O. Palsson. 2001. In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data. Nat. Biotechnol. 19:125-130.
8. Ibarra, R. U., J. S. Edwards, and B. O. Palsson. 2002. Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth. Nature. 420:186-189.
9. Neidhardt, F., J. L. Ingraham, and M. Shaechter. 1990 Physiology of the Bacterial Cell. Sinauer Associates, Sunderland, MA.
10. Yu, H., D. Greenbaum, L. H. Xin, X. Zhu, and M. Gerstein. 2004. Genomic analysis of essentiality within protein networks. Trends Genet. 20:227-231.