Facile preparation and purification of mono tert-butyl malonate

Synthetic Communications

Volumn 36, Issue 2, 2006, Pages 187-191

  Tararov, Vitali I ^a   Korostylev, Andrei ^a   König, Gerd ^b   Börner, Armin ^a,c  

^a LEIBNIZ INSTITUT FÜR KATALYSE E V AN DER UNIVERSITÄT ROSTOCK   (Germany)

^b ratiopharm GmbH   (Germany)

^c UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Half esterification; Malonic acid monoesters; tert butyl ester

Indexed keywords

MALONIC ACID DERIVATIVE; TERT BUTYLMALONATE; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; CHEMICAL REACTION; COST BENEFIT ANALYSIS; DECOMPOSITION; ESTERIFICATION; PURIFICATION;

EID: 31144444784     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397910500334405     Document Type: Article

References (9)

1. Jones, G. The Knoevenagel condensation. Org. React. 1967, 15, 204-599.
2. Brooks, D. W.; Lu, L. D.-L.; Masamune, S. C-Acylierung unter praktisch neutralen Bedingungen. Angew. Chem. 1979, 91, 76-77.
3. Brooks, D. W.; de Lee, N. C.; Peevey, R. Remote substituent effects in microbial reductions of 3-ketoglutarate and 3-ketoadipate esters. Tetrahedron Lett. 1984, 25, 4623-4626.
4. Junek, H.; Ziegler, E.; Herzog, U.; Kroboth, H. Eine einfache Synthese von Malonsäure - mono- und -bis-phenylestern. Synthesis 1976, 332-334.
5. Vogt, P. F.; Molino, B. F.; Robichaud, A. J. A Regiospecific synthesis of 3,3,6-trimethylindan-1-one. Synth. Commun. 2001, 31, 679-684.
6. Sato, M.; Ban, H.; Kaneko, C. An efficient method for generation of α-oxoketenes: Cycloreversion of enolized Meldrum's acid derivatives. Tetrahedron Lett. 1997, 38, 6689-6692.
7. Birney, D. M.; Xu, X.; Ham, S.; Huang, X. Chemoselectivity in the reaction of acetylketene and acetimidoylketene: Confirmation of theoretical predictions. J. Org. Chem. 1997, 62, 7114-7120.
8. Saito, Y.; Watanabe, T.; Hashimoto, H.; Yoshimura, J. Synthesis of N′-(p-glycosyl-oxycinnamoyl)spermidines. Carbohydr. Res. 1987, 169, 171-188.
9. Koskinen, A. M. P.; Munoz, L. Intramolecular cyclopropanation: Stereospecific synthesis of (E)- and (Z)-1-aminocyclopropane-1-carboxylic acids. J. Org. Chem. 1993, 58, 879-886.