메뉴 건너뛰기




Volumn 43, Issue 1, 2006, Pages 15-28

Feline large granular lymphocyte (LGL) lymphoma with secondary leukemia: Primary intestinal origin with predominance of a CD3/CD8aa phenotype

Author keywords

Cats; CD103 antigen; CD3 antigen; CD8 antigen; Immunohistochemistry; Intestines, small; Leukemia, large granular lymphocytic; Lymphocytes; Lymphoma, large granular lymphocytic

Indexed keywords

CD3 ANTIGEN; CD8 ANTIGEN; MONOCLONAL ANTIBODY;

EID: 31144440057     PISSN: 03009858     EISSN: 03009858     Source Type: Journal    
DOI: 10.1354/vp.43-1-15     Document Type: Article
Times cited : (78)

References (72)
  • 1
    • 0021873373 scopus 로고
    • Large granular lymphocytes from murine blood and intestinal epithelium: Comparison of surface antigens, natural killer activity, and morphology
    • Alberti S, Colotta F, Spreafico F, Delia D, Pasqualetto E, Luini W: Large granular lymphocytes from murine blood and intestinal epithelium: comparison of surface antigens, natural killer activity, and morphology. Clin Immunol Immunopathol 36:227-238, 1985
    • (1985) Clin Immunol Immunopathol , vol.36 , pp. 227-238
    • Alberti, S.1    Colotta, F.2    Spreafico, F.3    Delia, D.4    Pasqualetto, E.5    Luini, W.6
  • 2
    • 0024415764 scopus 로고
    • Low-grade intestinal lymphoma of intraepithelial T lymphocytes with concomitant enteropathy-associated T cell lymphoma: Case report suggesting a possible histogenetic relationship
    • Alfsen GC, Beiske K, Bell H, Marton PF: Low-grade intestinal lymphoma of intraepithelial T lymphocytes with concomitant enteropathy-associated T cell lymphoma: case report suggesting a possible histogenetic relationship. Hum Pathol 20:909-913, 1989
    • (1989) Hum Pathol , vol.20 , pp. 909-913
    • Alfsen, G.C.1    Beiske, K.2    Bell, H.3    Marton, P.F.4
  • 3
    • 0030811789 scopus 로고    scopus 로고
    • Molecular analysis of T-cell clonality in ulcerative jejunitis and enteropathy-associated T-cell lymphoma
    • Ashton-Key M, Diss TC, Pan L, Du MQ, Isaacson PG: Molecular analysis of T-cell clonality in ulcerative jejunitis and enteropathy-associated T-cell lymphoma. Am J Pathol 151:493-498, 1997
    • (1997) Am J Pathol , vol.151 , pp. 493-498
    • Ashton-Key, M.1    Diss, T.C.2    Pan, L.3    Du, M.Q.4    Isaacson, P.G.5
  • 4
    • 0033168262 scopus 로고    scopus 로고
    • Mucosal intra-epithelial lymphocytes in enteropathy-associated T-cell lymphoma, ulcerative jejunitis, and refractory celiac disease constitute a neoplastic population
    • Bagdi E, Diss TC, Munson P, Isaacson PG: Mucosal intra-epithelial lymphocytes in enteropathy-associated T-cell lymphoma, ulcerative jejunitis, and refractory celiac disease constitute a neoplastic population. Blood 94:260-264, 1999
    • (1999) Blood , vol.94 , pp. 260-264
    • Bagdi, E.1    Diss, T.C.2    Munson, P.3    Isaacson, P.G.4
  • 6
    • 0030140796 scopus 로고    scopus 로고
    • Histologic classification and immunophenotype of lymphosarcomas in cats with naturally and experimentally acquired feline immunodeficiency virus infections
    • Callanan JJ, Jones BA, Irvine J, Willett BJ, McCandlish IA, Jarrett O: Histologic classification and immunophenotype of lymphosarcomas in cats with naturally and experimentally acquired feline immunodeficiency virus infections. Vet Pathol 33:264-272, 1996
    • (1996) Vet Pathol , vol.33 , pp. 264-272
    • Callanan, J.J.1    Jones, B.A.2    Irvine, J.3    Willett, B.J.4    McCandlish, I.A.5    Jarrett, O.6
  • 8
    • 0027324601 scopus 로고
    • Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells
    • Cepek KL, Parker CM, Madara JL, Brenner MB: Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells. J Immunol 150:3459-3470, 1993
    • (1993) J Immunol , vol.150 , pp. 3459-3470
    • Cepek, K.L.1    Parker, C.M.2    Madara, J.L.3    Brenner, M.B.4
  • 11
    • 0027103760 scopus 로고
    • Peripheral T-cell lymphomas of the intestine
    • Chott A, Dragosics B, Radaszkiewicz T: Peripheral T-cell lymphomas of the intestine. Am J Pathol 141:1361-1371, 1992
    • (1992) Am J Pathol , vol.141 , pp. 1361-1371
    • Chott, A.1    Dragosics, B.2    Radaszkiewicz, T.3
  • 13
    • 0026766957 scopus 로고
    • Canine leukocyte cell adhesion molecules (LeuCAMs): Characterization of the CD11/CD18 family
    • Danilenko DM, Moore PF, Rossitto PV: Canine leukocyte cell adhesion molecules (LeuCAMs): characterization of the CD11/CD18 family. Tissue Antigens 40:13-21, 1992
    • (1992) Tissue Antigens , vol.40 , pp. 13-21
    • Danilenko, D.M.1    Moore, P.F.2    Rossitto, P.V.3
  • 14
    • 0029034170 scopus 로고
    • A novel canine leukointegrin, alpha d beta 2, is expressed by specific macrophage subpopulations in tissue and a minor CD8+ lymphocyte subpopulation in peripheral blood
    • Danilenko DM, Rossitto PV, Van der Vieren M, Le Trong H, McDonough SP, Affolter VK, Moore PF: A novel canine leukointegrin, alpha d beta 2, is expressed by specific macrophage subpopulations in tissue and a minor CD8+ lymphocyte subpopulation in peripheral blood. J Immunol 155:35-44, 1995
    • (1995) J Immunol , vol.155 , pp. 35-44
    • Danilenko, D.M.1    Rossitto, P.V.2    Van Der Vieren, M.3    Le Trong, H.4    McDonough, S.P.5    Affolter, V.K.6    Moore, P.F.7
  • 15
    • 0032161023 scopus 로고    scopus 로고
    • Large granular lymphocyte leukemia/lymphoma in six cats
    • Darbes J, Majzoub M, Breuer W, Hermanns W: Large granular lymphocyte leukemia/lymphoma in six cats. Vet Pathol 35:370-379, 1998
    • (1998) Vet Pathol , vol.35 , pp. 370-379
    • Darbes, J.1    Majzoub, M.2    Breuer, W.3    Hermanns, W.4
  • 17
    • 0033738690 scopus 로고    scopus 로고
    • Enteropathy associated T-cell lymphoma: A case report and literature review
    • Dieter R, Dunque K: Enteropathy associated T-cell lymphoma: a case report and literature review. Wis Med J 99:28-31, 2000
    • (2000) Wis Med J , vol.99 , pp. 28-31
    • Dieter, R.1    Dunque, K.2
  • 18
  • 21
    • 0015368561 scopus 로고
    • A neoplasm of globule leucocytes in the intestine of a cat
    • Finn JP, Schwartz LW: A neoplasm of globule leucocytes in the intestine of a cat. J Comp Pathol 82:323-326, 1972
    • (1972) J Comp Pathol , vol.82 , pp. 323-326
    • Finn, J.P.1    Schwartz, L.W.2
  • 23
    • 2342663130 scopus 로고    scopus 로고
    • The CD8 isoform CD8alphaalpha is not a functional homologue of the TCR co-receptor CD8alphabeta
    • Gangadharan D, Cheroutre H: The CD8 isoform CD8alphaalpha is not a functional homologue of the TCR co-receptor CD8alphabeta. Curr Opin Immunol 16:264-270, 2004
    • (2004) Curr Opin Immunol , vol.16 , pp. 264-270
    • Gangadharan, D.1    Cheroutre, H.2
  • 27
    • 0024416277 scopus 로고
    • Immunophenotypic characterization of an unusual T-cell lymphoma presenting as anterior uveitis. A clinicopathologic case report
    • Goldey SH, Stern GA, Oblon DJ, Mendenhall NP, Smith LJ, Duque RE: Immunophenotypic characterization of an unusual T-cell lymphoma presenting as anterior uveitis. A clinicopathologic case report. Arch Ophthalmol 107:1349-1353, 1989
    • (1989) Arch Ophthalmol , vol.107 , pp. 1349-1353
    • Goldey, S.H.1    Stern, G.A.2    Oblon, D.J.3    Mendenhall, N.P.4    Smith, L.J.5    Duque, R.E.6
  • 28
    • 0346695182 scopus 로고
    • Hematopoietic tumors
    • ed. Withrow S and MacEwen E, J B Lippincott Co, Philadelphia, PA
    • Hardy W, McEwen E: Hematopoietic tumors. In: Clinical Veterinary Oncology, ed. Withrow S and MacEwen E, pp. 362-411. J B Lippincott Co, Philadelphia, PA, 1989
    • (1989) Clinical Veterinary Oncology , pp. 362-411
    • Hardy, W.1    McEwen, E.2
  • 29
    • 0035162229 scopus 로고    scopus 로고
    • Intraepithelial lymphocytes: Exploring the Third Way in immunology
    • Hayday A, Theodoridis E, Ramsburg E, Shires J: Intraepithelial lymphocytes: exploring the Third Way in immunology. Nat Immunol 2:997-1003, 2001
    • (2001) Nat Immunol , vol.2 , pp. 997-1003
    • Hayday, A.1    Theodoridis, E.2    Ramsburg, E.3    Shires, J.4
  • 31
    • 0032912217 scopus 로고    scopus 로고
    • Gastrointestinal lymphomas of T- and B-cell types
    • Isaacson PG: Gastrointestinal lymphomas of T- and B-cell types. Mod Pathol 12:151-158, 1999
    • (1999) Mod Pathol , vol.12 , pp. 151-158
    • Isaacson, P.G.1
  • 32
    • 0027761437 scopus 로고
    • Large granular lymphoma with toxoplasmosis in a cat
    • Jarplid B, Feldman B: Large granular lymphoma with toxoplasmosis in a cat. Comp Haematol Int 3:241-243, 1993
    • (1993) Comp Haematol Int , vol.3 , pp. 241-243
    • Jarplid, B.1    Feldman, B.2
  • 33
  • 34
    • 0027300658 scopus 로고
    • Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies
    • Jones M, Cordell JL, Beyers AD, Tse AG, Mason DY: Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies. J Immunol 150:5429-5435, 1993
    • (1993) J Immunol , vol.150 , pp. 5429-5435
    • Jones, M.1    Cordell, J.L.2    Beyers, A.D.3    Tse, A.G.4    Mason, D.Y.5
  • 35
    • 0023792668 scopus 로고
    • A primary immunoblastic T malignant lymphoma of the small bowel, with azurophilic intracytoplasmic granules. A histologic, immunologic, and electron microscopy study
    • Kanavaros P, Lavergne A, Galian A, Boivin P, Fourmestreaux AR, Priollet BC, Flandrin G, Hautefeuille P: A primary immunoblastic T malignant lymphoma of the small bowel, with azurophilic intracytoplasmic granules. A histologic, immunologic, and electron microscopy study. Am J Surg Pathol 12:641-647, 1988
    • (1988) Am J Surg Pathol , vol.12 , pp. 641-647
    • Kanavaros, P.1    Lavergne, A.2    Galian, A.3    Boivin, P.4    Fourmestreaux, A.R.5    Priollet, B.C.6    Flandrin, G.7    Hautefeuille, P.8
  • 37
    • 0031092936 scopus 로고    scopus 로고
    • Perforin-like immunoreactivity in four cases of lymphoma of large granular lymphocytes in the cat
    • Kariya K, Konno A, Ishida T: Perforin-like immunoreactivity in four cases of lymphoma of large granular lymphocytes in the cat. Vet Pathol 34:156-159, 1997
    • (1997) Vet Pathol , vol.34 , pp. 156-159
    • Kariya, K.1    Konno, A.2    Ishida, T.3
  • 38
    • 0025039030 scopus 로고
    • A new surface antigen on intraepithelial lymphocytes in the intestine
    • Kilshaw PJ, Murant SJ: A new surface antigen on intraepithelial lymphocytes in the intestine. Eur J Immunol 20:2201-2207, 1990
    • (1990) Eur J Immunol , vol.20 , pp. 2201-2207
    • Kilshaw, P.J.1    Murant, S.J.2
  • 40
    • 0038491347 scopus 로고    scopus 로고
    • Clinical features of large granular lymphocyte leukemia
    • Lamy T, Loughran TP Jr: Clinical features of large granular lymphocyte leukemia. Semin Hematol 40:185-195, 2003
    • (2003) Semin Hematol , vol.40 , pp. 185-195
    • Lamy, T.1    Loughran Jr., T.P.2
  • 41
    • 0033508739 scopus 로고    scopus 로고
    • Current concepts: Large granular lymphocyte leukemia
    • Lamy T, Loughran TP Jr: Current concepts: large granular lymphocyte leukemia. Blood Rev 13:230-240, 1999
    • (1999) Blood Rev , vol.13 , pp. 230-240
    • Lamy, T.1    Loughran Jr., T.P.2
  • 42
    • 0026762701 scopus 로고
    • Acquired immunodeficiency syndrome-related lymphoma
    • Levine AM: Acquired immunodeficiency syndrome-related lymphoma. Blood 80:8-20, 1992
    • (1992) Blood , vol.80 , pp. 8-20
    • Levine, A.M.1
  • 43
    • 0025157274 scopus 로고
    • Aggressive jejunal lymphoma of large granular lymphocytes. Immunohistochemical, ultrastructural, molecular, and DNA content analysis
    • Longacre TA, Listrom MB, Spigel JH, Willman CL, Dressler L, Clark D: Aggressive jejunal lymphoma of large granular lymphocytes. Immunohistochemical, ultrastructural, molecular, and DNA content analysis. Am J Clin Pathol 93:124-132, 1990
    • (1990) Am J Clin Pathol , vol.93 , pp. 124-132
    • Longacre, T.A.1    Listrom, M.B.2    Spigel, J.H.3    Willman, C.L.4    Dressler, L.5    Clark, D.6
  • 44
    • 0027300176 scopus 로고
    • Clonal diseases of large granular lymphocytes
    • Loughran TP Jr: Clonal diseases of large granular lymphocytes. Blood 82:1-14, 1993
    • (1993) Blood , vol.82 , pp. 1-14
    • Loughran Jr., T.P.1
  • 45
    • 0026646058 scopus 로고
    • Isolation of functionally active intraepithelial lymphocytes and enterocytes from human small and large intestine
    • Lundqvist C, Hammarstrom ML, Athlin L, Hammarstrom S: Isolation of functionally active intraepithelial lymphocytes and enterocytes from human small and large intestine. J Immunol Methods 152:253-263, 1992
    • (1992) J Immunol Methods , vol.152 , pp. 253-263
    • Lundqvist, C.1    Hammarstrom, M.L.2    Athlin, L.3    Hammarstrom, S.4
  • 47
    • 0034330478 scopus 로고    scopus 로고
    • Clinical, hematologic, and immunophenotypic characterization of canine large granular lymphocytosis
    • McDonough SP, Moore PF: Clinical, hematologic, and immunophenotypic characterization of canine large granular lymphocytosis. Vet Pathol 37:637-646, 2000
    • (2000) Vet Pathol , vol.37 , pp. 637-646
    • McDonough, S.P.1    Moore, P.F.2
  • 49
    • 0025641715 scopus 로고
    • Canine leukocyte integrins: Characterization of a CD18 homologue
    • Moore PF, Rossitto PV, Danilenko DM: Canine leukocyte integrins: characterization of a CD18 homologue. Tissue Antigens 36:211-220, 1990
    • (1990) Tissue Antigens , vol.36 , pp. 211-220
    • Moore, P.F.1    Rossitto, P.V.2    Danilenko, D.M.3
  • 51
    • 4544270913 scopus 로고    scopus 로고
    • Downmodulation of CD3epsilon expression in CD8alpha+beta- T cells of feline immunodeficiency virus-infected cats
    • Nishimura Y, Shimojima M, Sato E, Izumiya Y, Tohya Y, Mikami T, Miyazawa T: Downmodulation of CD3epsilon expression in CD8alpha+beta- T cells of feline immunodeficiency virus-infected cats. J Gen Virol 85:2585-2589, 2004
    • (2004) J Gen Virol , vol.85 , pp. 2585-2589
    • Nishimura, Y.1    Shimojima, M.2    Sato, E.3    Izumiya, Y.4    Tohya, Y.5    Mikami, T.6    Miyazawa, T.7
  • 53
    • 0026669494 scopus 로고
    • Biologic and clinical heterogeneity of lymphoproliferative diseases of peripheral mature T lymphocytes
    • Pandolfi F, Zambello R, Cafaro A, Semenzato G: Biologic and clinical heterogeneity of lymphoproliferative diseases of peripheral mature T lymphocytes. Lab Invest 67:274-302, 1992
    • (1992) Lab Invest , vol.67 , pp. 274-302
    • Pandolfi, F.1    Zambello, R.2    Cafaro, A.3    Semenzato, G.4
  • 54
    • 0025917134 scopus 로고
    • Phenotypic analysis of malignant lymphoma in simian immunodeficiency virus infection using antihuman antibodies
    • Ramsay AD, Giddings J, Baskerville A, Cranage MP: Phenotypic analysis of malignant lymphoma in simian immunodeficiency virus infection using antihuman antibodies. J Pathol 164:321-328, 1991
    • (1991) J Pathol , vol.164 , pp. 321-328
    • Ramsay, A.D.1    Giddings, J.2    Baskerville, A.3    Cranage, M.P.4
  • 55
    • 0025606135 scopus 로고
    • Distribution of MHC class II antigens in feline tissues and peripheral blood
    • Rideout BA, Moore PF, Pedersen NC: Distribution of MHC class II antigens in feline tissues and peripheral blood. Tissue Antigens 36:221-227, 1990
    • (1990) Tissue Antigens , vol.36 , pp. 221-227
    • Rideout, B.A.1    Moore, P.F.2    Pedersen, N.C.3
  • 56
    • 0034734046 scopus 로고    scopus 로고
    • Characterization of the diffuse mucosal associated lymphoid tissue of feline small intestine
    • Roccabianca P, Woo JC, Moore PF: Characterization of the diffuse mucosal associated lymphoid tissue of feline small intestine. Vet Immunol Immunopathol 75:27-42, 2000
    • (2000) Vet Immunol Immunopathol , vol.75 , pp. 27-42
    • Roccabianca, P.1    Woo, J.C.2    Moore, P.F.3
  • 58
    • 0028791672 scopus 로고
    • Isolation and characterization of intraepithelial lymphocytes from rat small intestine
    • Santhi G, Ramanadham M: Isolation and characterization of intraepithelial lymphocytes from rat small intestine. Indian J Exp Biol 33:926-930, 1995
    • (1995) Indian J Exp Biol , vol.33 , pp. 926-930
    • Santhi, G.1    Ramanadham, M.2
  • 60
    • 0023727525 scopus 로고
    • Enteropathy-associated T cell lymphoma (malignant histiocytosis of the intestine) is recognized by a monoclonal antibody (HML-1) that defines a membrane molecule on human mucosal lymphocytes
    • Spencer J, Cerf-Bensussan N, Jarry A, Brousse N, Guy-Grand D, Krajewski AS, Isaacson PG: Enteropathy-associated T cell lymphoma (malignant histiocytosis of the intestine) is recognized by a monoclonal antibody (HML-1) that defines a membrane molecule on human mucosal lymphocytes. Am J Pathol 132:1-5, 1988
    • (1988) Am J Pathol , vol.132 , pp. 1-5
    • Spencer, J.1    Cerf-Bensussan, N.2    Jarry, A.3    Brousse, N.4    Guy-Grand, D.5    Krajewski, A.S.6    Isaacson, P.G.7
  • 61
    • 0029024613 scopus 로고
    • Development of human T and natural killer cells
    • Spits H, Lanier LL, Phillips JH: Development of human T and natural killer cells. Blood 85:2654-2670, 1995
    • (1995) Blood , vol.85 , pp. 2654-2670
    • Spits, H.1    Lanier, L.L.2    Phillips, J.H.3
  • 62
    • 0035284821 scopus 로고    scopus 로고
    • Integrin alpha E(CD103)beta 7 mediates adhesion to intestinal microvascular endothelial cell lines via an E-cadherin-independent interaction
    • Strauch UG, Mueller RC, Li XY, Cernadas M, Higgins JM, Binion DG, Parker CM: Integrin alpha E(CD103)beta 7 mediates adhesion to intestinal microvascular endothelial cell lines via an E-cadherin-independent interaction. J Immunol 166:3506-3514, 2001
    • (2001) J Immunol , vol.166 , pp. 3506-3514
    • Strauch, U.G.1    Mueller, R.C.2    Li, X.Y.3    Cernadas, M.4    Higgins, J.M.5    Binion, D.G.6    Parker, C.M.7
  • 63
    • 0032857813 scopus 로고    scopus 로고
    • An immunophenotypic study of canine leukemias and preliminary assessment of clonality by polymerase chain reaction
    • Vernau W, Moore PF: An immunophenotypic study of canine leukemias and preliminary assessment of clonality by polymerase chain reaction. Vet Immunol Immunopathol 69:145-164, 1999
    • (1999) Vet Immunol Immunopathol , vol.69 , pp. 145-164
    • Vernau, W.1    Moore, P.F.2
  • 65
  • 67
    • 0020104866 scopus 로고
    • Isolation of viable canine intestinal lymphocytes
    • Willard MD, Bull RW, Coffman PJ: Isolation of viable canine intestinal lymphocytes. Am J Vet Res 43:471-474, 1982
    • (1982) Am J Vet Res , vol.43 , pp. 471-474
    • Willard, M.D.1    Bull, R.W.2    Coffman, P.J.3
  • 68
    • 0030754327 scopus 로고    scopus 로고
    • Immunopathologic changes in the thymus during the acute stage of experimentally induced feline immunodeficiency virus infection in juvenile cats
    • Woo JC, Dean GA, Pedersen NC, Moore PF: Immunopathologic changes in the thymus during the acute stage of experimentally induced feline immunodeficiency virus infection in juvenile cats. J Virol 71:8632-8641, 1997
    • (1997) J Virol , vol.71 , pp. 8632-8641
    • Woo, J.C.1    Dean, G.A.2    Pedersen, N.C.3    Moore, P.F.4
  • 69
    • 0030947982 scopus 로고    scopus 로고
    • A feline homologue of CD1 is defined using a feline-specific monoclonal antibody
    • Woo JC, Moore PF: A feline homologue of CD1 is defined using a feline-specific monoclonal antibody. Tissue Antigens 49:244-251, 1997
    • (1997) Tissue Antigens , vol.49 , pp. 244-251
    • Woo, J.C.1    Moore, P.F.2
  • 70
    • 0036178122 scopus 로고    scopus 로고
    • Characterization of a feline homologue of the alphaE integrin subunit (CD103) reveals high specificity for intra-epithelial lymphocytes
    • Woo JC, Roccabianca P, van Stijn A, Moore PF: Characterization of a feline homologue of the alphaE integrin subunit (CD103) reveals high specificity for intra-epithelial lymphocytes. Vet Immunol Immunopathol 85:9-22, 2002
    • (2002) Vet Immunol Immunopathol , vol.85 , pp. 9-22
    • Woo, J.C.1    Roccabianca, P.2    Van Stijn, A.3    Moore, P.F.4
  • 71
    • 0030768736 scopus 로고    scopus 로고
    • Enteropathy associated T cell lymphoma
    • Wright DH: Enteropathy associated T cell lymphoma. Cancer Surv 30:249-261, 1997
    • (1997) Cancer Surv , vol.30 , pp. 249-261
    • Wright, D.H.1
  • 72
    • 0028887058 scopus 로고
    • Monoclonal proliferation of CD4+ large granular lymphocytes with cytolytic activity
    • Yasukawa M, Utsunomiya Y, Inoue Y, Kimura N, Fujita S: Monoclonal proliferation of CD4+ large granular lymphocytes with cytolytic activity. Br J Haematol 91:419-420, 1995
    • (1995) Br J Haematol , vol.91 , pp. 419-420
    • Yasukawa, M.1    Utsunomiya, Y.2    Inoue, Y.3    Kimura, N.4    Fujita, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.