Proline-catalyzed, asymmetric Mannich reactions in the synthesis of a DPP-IV inhibitor

Journal of Organic Chemistry

Volumn 71, Issue 1, 2006, Pages 390-392

  Janey, Jacob M ^a   Hsiao, Yi ^a   Armstrong III, Joseph D ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; AMINO ACIDS; CATALYSIS; DERIVATIVES; REACTION KINETICS; SUBSTITUTION REACTIONS;

ACETALDEHYDES; ASPARTIC ACID DERIVATIVES; MANNICH ADDUCTS; MANNICH REACTION;

STEREOCHEMISTRY;

ACETALDEHYDE; ASPARTIC ACID DERIVATIVE; BENZENE DERIVATIVE; DIPEPTIDYL PEPTIDASE IV INHIBITOR; GLYOXYLIC ACID; HOMOSERINE; IMINE; PROLINE;

ARTICLE; CATALYSIS; CROSS COUPLING REACTION; DIASTEREOISOMER; DRUG SYNTHESIS; EPIMERIZATION; MANNICH REACTION; POLYMERIZATION; REACTION ANALYSIS; STEREOCHEMISTRY;

ALDEHYDES; AMINO ALCOHOLS; ANTIGENS, CD26; CATALYSIS; MOLECULAR STRUCTURE; PROLINE; PROTEASE INHIBITORS; STEREOISOMERISM;

EID: 31144436810     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0519458     Document Type: Article

References (17)

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