Risks of transmission of variant Creutzfeldt-Jakob disease by blood transfusion

Folia Neuropathologica

Volumn 43, Issue 4, 2005, Pages 271-278

  Peden, Alexander H ^a   Ritchie, Diane L ^a   Ironside, James W ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Blood transfusion; Infectivity; Transmission; Variant Creutzfeldt Jakob disease

Indexed keywords

PRION PROTEIN;

AUTOPSY; BLOOD DONOR; BLOOD TRANSFUSION; BOVINE SPONGIFORM ENCEPHALOPATHY; CREUTZFELDT JAKOB DISEASE; DISEASE ASSOCIATION; DISEASE TRANSMISSION; ENZYME LINKED IMMUNOSORBENT ASSAY; HIGH RISK PATIENT; HUMAN; IATROGENIC DISEASE; INCUBATION TIME; LYMPHOID TISSUE; MORTALITY; NONHUMAN; PRION DISEASE; PROTEIN ANALYSIS; PROTEIN DETERMINATION; REVIEW; RISK ASSESSMENT; SCREENING TEST; SENSITIVITY ANALYSIS; UNITED KINGDOM; VIRUS INFECTIVITY; WESTERN BLOTTING;

ANIMALS; BLOOD TRANSFUSION; CATTLE; CREUTZFELDT-JAKOB SYNDROME; ENCEPHALOPATHY, BOVINE SPONGIFORM; GREAT BRITAIN; HUMANS;

EID: 30944451759     PISSN: 16414640     EISSN: 1509572X     Source Type: Journal    
DOI: None     Document Type: Review

References (42)

1. Aguzzi A. Prion diseases, blood and the immune system: concerns and reality. Haematologica 2000; 85: 3-10.
2. Alperovitch A, Zerr I, Pocchiari M, Mitrova E, de Pedro Cuesta J, Hegyi I, Collins S, Kretzschmar H, van Duijn C, Will RG. Codon 129 prion protein genotype and sporadic Creutzfeldt-Jakob disease. Lancet 1999; 353: 1673-1674.
3. Bellon A, Seyfert-Brandt W, Lang W, Baron H, Groner A, Vey M. Improved conformation-dependent immunoassay: suitability for human prion detection with enhanced sensitivity. J Gen Virol 2003; 84: 1921-1925.
4. Biffiger K, Zwald D, Kaufmann L, Briner A, Nayki I, Purro M, Bottcher S, Struckmeyer T, Schaller O, Meyer R, Fatzer R, Zurbriggen A, Stack M, Moser M, Oesch B, Kubler E. Validation of a luminescence immunoassay for the detection of PrP(Sc) in brain homogenate. J Virol Methods 2002; 101: 79-84.
5. Brown P. Can Creutzfeldt-Jakob disease be transmitted by transfusion? Curr Opin Haematol 1995; 2: 472-477.
6. Brown P, Gibbs CJ Jr, Rodgers-Johnson P, Asher DM, Sulima MP, Bacote A, Goldfarb LG, Gajdusek DC. Human spongiform encephalopathy: the National Institutes of Health series of 300 cases of experimentally transmitted disease. Ann Neurol 1994; 35: 513-529.
7. Bruce ME, McConnell I, Will RG, Ironside JW. Detection of variant Creutzfeldt-Jakob disease infectivity in extraneural tissues. Lancet 2001; 358: 208-209.
8. Bruce ME, Will RG, Ironside JW, McConnell I, Drummond D, Suttie A, McCardle L, Chree A, Hope J, Birkett C, Cousens S, Fraser H, Bostock CJ. Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent. Nature. 1997; 389: 498-501.
9. Castilla J, Saa P, Herz C, Soto C. In vitro generation of infectious scrapie prions. Cell 2005; 121: 195-206.
10. Castilla J, Saa P, Soto C. Detection of prions in blood. Nat Med. 2005; 11: 982-985.
11. Cervenakova L, Yakoleva O, McKenzie C, Kolchinsky S, McShane L, Drohan WN, Brown P. Similar levels of infectivity in the blood of mice infected with human-derived vCJD and GSS strains of transmissible spongiform encephalopathy. Transfusion 2003; 43: 1687-1694.
12. Deslys JP, Comoy E, Hawkins S, Simon S, Schimmel H, Wells G, Grassi J, Moynagh J. Screening slaughtered cattle for BSE. Nature 2001; 409: 476-478.
13. Det Norske Veritas 2004. Risk of infection from variant CJD in blood. http://www.dnv.co.uk/Binaries/vCJD_Update_Report_tcm27- 74414.pdf
14. Fagge T, Barclay GR, MacGregor I, Head M, Ironside J, Turner M. Variation in concentration of prion protein in the peripheral blood of patients with variant and sporadic Creutzfeldt-Jakob disease detected by dissociation enhanced lanthanide fluoroimmunoassay and flow cytometry. Transfusion 2005; 44: 504-513.
15. Goldfarb LG, Cervenakova L, Gajdusek DC. Genetic studies in relation to kuru: an overview. Curr Mol Med 2004; 4: 375-384.
16. Haik S, Faucheux BA, Sazdovitch V, Privat N, Kemeney JL, Perret-Liaudet A, Hauw JJ. The sympathetic nervous system is involved in variant Creutzfeldt-Jakob disease. Nat Med 2003; 9: 1121-1123.
17. Head MW, Bunn TJ, Bishop MT, McLoughlin V, Lowrie S, McKimmie CS, Williams MC, McCardle L, MacKenzie J, Knight R, Will RG, Ironside JW. Prion protein heterogeneity in sporadic but not variant Creutzfeldt-Jakob disease: UK cases 1991-2002. Ann Neurol 2004; 55: 851-859.
18. Head MW, Ironside JW. Inhibition of prion-protein conversion-a therapeutic tool? Trends Microbiol 2000; 8: 6-8.
19. Head MW, Ritchie D, Smith N, McLoughlin V, Nailon W, Samad S, Masson S, Bishop M, McCardle L, Ironside JW. Peripheral tissue involvement in sporadic, iatrogenic and variant Creutzfeldt-Jakob disease: an immunohistochemical, quantitative and biochemical study. Am J Pathol 2004; 164: 143-153.
20. Hill AF, Butterworth RJ, Joiner S, Jackson G, Rosser MN, Thomas DJ, Frosh A, Tolley N, Bell JE, Spencer M, King A, Al-Sarraj S, Ironside JW, Lantos PL, Collinge J. Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. Lancet 1999; 353: 183-189.
21. Hill AF, Zeidler M, Ironside JW, Collinge J. Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy. Lancet 1997; 349: 99-100.
22. Hilton DA, Fathers E, Edwards P, Ironside JW, Zajicek J. Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease. Lancet 1998; 352: 703-704.
23. Hilton DA, Ghani AC, Conyers L, Edwards P, McCardle L, Ritchie D, Penney M, Hegazy D, Ironside JW. Prevalence of lymphoreticular prion protein accumulation in UK tissue samples. J Pathol 2004; 203: 733-739.
24. Houston F, Foster JD, Chong A, Hunter N, Bostock CT. Transmission of BSE by blood transfusion in sheep. Lancet 2000; 356: 999-1000.
25. Hunter N, Foster J, Chong A, McCutcheon S, Parnham D, Eaton S, Mackenzie C Houston F. Transmission of prion diseases by blood transfusion. J Gen Virol 2002; 83: 2897-2905.
26. Ironside JW, Head MW, Bell JE, McCardle L, Will RG. Laboratory diagnosis of variant Creutzfeldt-Jakob disease. Histopathology 2000; 37: 1-9.
27. Ironside JW, McCardle L, Horsburgh A, Lim Z, Head MW. Pathological diagnosis of variant Creutzfeldt-Jakob disease. APMIS 2002; 110: 79-87.
28. Llewelyn CA, Hewitt PE, Knight RS, Amar K, Cousens S, Mackenzie J, Will RG. Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. Lancet 2004; 363: 417-421.
29. MacGregor I. Prion protein and developments in its detection. Transfusion Med 2001; 11: 3-14.
30. Manuelidis EE, Kim JH, Mericangas JR, Manuelidis L Transmission to animals of Creutzfeldt-Jakob disease from Human Blood. Lancet 1985; ii: 896-897.
31. Moynagh J, Schimmel H. Tests for BSE evaluated. Bovine spongiform encephalopathy. Nature 1999; 400: 105.
32. Peden AH, Head MW, Ritchie DL, Bell JE, Ironside JW. Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient. Lancet 2004; 364: 527-529.
33. Saborio GP, Permanne B, Soto C. Sensitive detection of pathological prion protein by cyclical amplification of protein misfolding. Nature 2001; 411: 810-813.
34. Safar JG, Scott M, Monaghan J, Deering C, Didorenko S, Vergara J, Ball H, Legname G, Leclerc E, Solforosi L, Serban H, Groth D, Burton, DR, Prusiner SB, Williamson RA. Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice. Nat Biotechnol 2002; 20: 1147-1150.
35. Safar JG, Geschwind MD, Deering C, Didorenko S, Sattavat M, Sanchez H, Serban A, Vey M, Baron H, Giles K, Miller BL, DeArmond SJ, Prusiner SB. Diagnosis of human prion disease. Proc Natl Acad Sci USA 2005; 102: 3501-3506.
36. Scott MR, Will R, Ironside J, Nguyen HO, Tremblay P, DeArmond SJ, Prusiner SB. Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans. Proc Natl Acad Sci USA 1999; 96: 15137-15142.
37. Turner ML. Variant Creutzfeldt-Jakob disease and blood transfusion. Curr Opin Hematol 2001; 8: 372-379.
38. Turner ML, Ironside JW. New-variant Creutzfeldt-Jakob disease: the risk of transmission by blood transfusion. Blood Rev 1998; 12: 255-268.
39. Wadsworth JD, Joiner S, Hill AF, Campbell TA, Desbruslais M, Luthert PJ, Collinge J. Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay. Lancet 2001; 358: 171-180.
40. Weissmann C, Raeber AJ, Montrasio F, Hegyi I, Frigg R, Klein MA, Aguzzi A. Prions and the lymphoreticular system. Philos Trans T Soc Lond B Biol Sci 2001; 356: 177-184.
41. Will RG, Ironside JW, Zeidler M, Cousens SN, Estibeiro K, Alperovitch A, Poser S, Pocchiari M, Hofman A, Smith PG. A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 1996; 347: 921-925.
42. Will RG, Kimberlin RH. Creutzfeldt-Jakob disease and the risk from blood or blood products. Vox Sanguin 1998; 75: 178-180.