Presence and co-localization of vasoactive intestinal polypeptide with neuronal nitric oxide synthase in cells and nerve fibers within guinea pig intrinsic cardiac ganglia and cardiac tissue

Cell and Tissue Research

Volumn 323, Issue 2, 2006, Pages 197-209

  Parsons, R L ^a   Locknar, S A ^a   Young, B A ^a   Hoard, J L ^b   Hoover, D B ^b  

^a UNIVERSITY OF VERMONT   (United States)

^b East Tennessee State University   (United States)

Author keywords

Autonomic neuron; Guinea pig (Hartley); Intrinsic cardiac ganglia; Neuropeptide; Vagal afferent fibers

Indexed keywords

CHOLINE ACETYLTRANSFERASE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; NEURONAL NITRIC OXIDE SYNTHASE; NEUROPEPTIDE; SUBSTANCE P; TYROSINE 3 MONOOXYGENASE; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CELL CULTURE; CONNECTIVE TISSUE; CONTROLLED STUDY; GUINEA PIG; HEART; HEART ATRIUM; HEART ATRIUM MUSCLE; HEART MUSCLE CONDUCTION SYSTEM; HEART VENTRICLE WALL; IMMUNOREACTIVITY; NERVE CELL; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; SENSORY GANGLION; SINUS NODE; TISSUE SECTION;

AFFERENT PATHWAYS; ANIMALS; FEMALE; GANGLIA, PARASYMPATHETIC; GUINEA PIGS; HEART ATRIA; HEART CONDUCTION SYSTEM; HEART VENTRICLES; MALE; MYOCARDIUM; NERVE FIBERS; NEURONS, AFFERENT; NITRIC OXIDE SYNTHASE TYPE I; ORGAN CULTURE TECHNIQUES; VASOACTIVE INTESTINAL PEPTIDE;

ANIMALIA; CAVIA PORCELLUS;

EID: 30744475433     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00441-005-0074-3     Document Type: Article

References (37)

1. Anderson FL, Hanson GR, Reid B, Thorpe M, Kralios AC (1993) VIP and NPY in canine hearts. Distribution and effect of total and selective parasympathetic denervation. Am J Physiol 265:H91-H95
2. Ardell JL (2001) Neurohumoral control of cardiac function. In: Sperelakis N (ed) Heart physiology and pathophysiology. Academic, San Diego, pp 45-59
3. Arimura A (1998) Perspectives on pituitary adenylate cyclase activating polypeptide (PACAP) in the neuroendocrine, endocrine, and nervous systems. Jpn J Physiol 48:301-331
4. Braas KM, May V, Harakall SA, Hardwick JC, Parsons RL (1998) Pituitary adenylate cyclase-activating polypeptide expression and modulation of neuronal excitability in guinea pig cardiac ganglia. J Neurosci 18:9766-9779
5. Braas KM, Rossignol TM, Girard BM, May V, Parsons RL (2004) Pituitary adenylate cyclase activating polypeptide (PACAP) decreases neuronal somatostatin immunoreactivity in cultured guinea-pig parasympathetic ganglia. Neuroscience 126:335-346
6. Calupca MA, Vizzard MA, Parsons RL (2000a) Origin of pituitary adenylate cyclase-activating polypeptide (PACAP)-immunoreactive fibers innervating guinea pig parasympathetic cardiac ganglia. J Comp Neurol 423:26-39
7. Calupca MA, Vizzard MA, Parsons RL (2000b) Origin of neuronal nitric oxide synthase (NOS)-immunoreactive fibers in guinea pig parasympathetic cardiac ganglia. J Comp Neurol 426:493-504
8. Chang Y, Lawson LJ, Hancock JC, Hoover DB (2005) Pituitary adenylate cyclase-activating polypeptide: localization and differential influence on isolated hearts from rats and guinea pigs. Regul Pept 129:139-146
9. Crick SJ, Wharton J, Sheppard MN, Royston D, Yacoub MH, Anderson RH, Polak JM (1994) Innervation of the human cardiac conduction system. A quantitative immunohistochemical and histochemical study. Circulation 89:1697-1708
10. Della NG, Papka RE, Furness JB, Costa M (1983) Vasoactive intestinal peptide-like immunoreactivity in nerves associated with the cardiovascular system of guinea-pigs. Neuroscience 9:605-619
11. Fahrenkrug J, Hannibal J (2004) Neurotransmitters co-existing with VIP or PACAP. Peptides 25:393-401
12. Forsgren S (1989) Vasoactive intestinal polypeptide-like immunoreactivity in the bovine heart: high degree of coexistence with neuropeptide Y-like immunoreactivity. Cell Tissue Res 256:125-135
13. Hardwick JC, Mawe GM, Parsons RL (1995) Evidence for afferent fiber innervation of parasympathetic neurons of the guinea pig cardiac ganglion. J Auton Nerv Syst 53:166-174
14. 3 neurokinin receptors in guinea-pig intracardiac neurons. J Physiol (Lond) 504:65-74
15. Henning RJ, Sawmiller DR (2001) Vasoactive intestinal peptide: cardiovascular effects. Cardiovasc Res 49:27-37
16. Hoover DB (1989) Effects of guinea pig vasoactive intestinal peptide on the isolated perfused guinea pig heart. Peptides 10:343-347
17. Hoover DB, Ganote CE, Ferguson SM, Blakely RD, Parsons RL (2004) Localization of cholinergic innervation in guinea pig heart by immunohistochemistry for high-affinity choline transporters. Cardiovasc Res 62:112-121
18. Horackova M, Armour JA, Byczko Z (1999) Distribution of intrinsic cardiac neurons in whole-mount guinea pig atria identified by multiple neurochemical coding. A confocal microscope study. Cell Tissue Res 297:409-421
19. Hyatt-Sachs H, Schreiber RC, Bennett TA, Zigmond RE (1993) Phenotypic plasticity in adult sympathetic ganglia in vivo: effects of deafferentation and axotomy on the expression of vasoactive intestinal peptide. J Neurosci 13:1642-1653
20. Kennedy AL, Harakall SA, Lynch SW, Braas KM, Hardwick JC, Mawe GM, Parsons RL (1998) Expression and physiological actions of neuropeptide Y in guinea pig parasympathetic cardiac ganglia. J Auton Nerv Syst 71:190-195
21. Leger J, Croll RP, Smith FM (1999) Regional distribution and extrinsic innervation of intrinsic cardiac neurons in the guinea pig. J Comp Neurol 407:303-317
22. Liu D-M, Cuevas J, Adams DJ (2000) VIP and PACAP potentiation of nicotinic ACh-evoked currents in rat parasympathetic neurons is mediated by G-protein activation. Eur J Neurosci 12:2243-2251
23. Loffelholz K, Pappano AJ (1985) The parasympathetic neuroeffector junction of the heart. Pharmacol Rev 37:1-24
24. Lynch SW, Braas KM, Harakall SA, Kennedy AL, Mawe GM, Parsons RL (1999) Neuropeptide Y (NPY) expression is increased in explanted guinea pig parasympathetic cardiac ganglia neurons. Brain Res 827:70-78
25. Mawe GM, Ellis LM (2001) Chemical coding of intrinsic and extrinsic nerves in the guinea pig gallbladder: distributions of PACAP and orphanin FQ. Anat Rec 262:101-109
26. Mawe GM, Talmage EK, Lee KP, Parsons RL (1996) Expression of choline acetyltransferase immunoreactivity in guinea pig cardiac ganglia. Cell Tissue Res 285:281-286
27. h, in dissociated guinea pig intracardiac neurons. Regul Pept 123:123-133
28. Moller K, Reimer M, Ekblad E, Hannibal J, Fahrenkrug J, Kanje M, Sundler F (1997) The effects of axotomy and preganglionic denervation on the expression of pituitary adenylate cyclase activating peptide (PACAP), galanin and PACAP type 1 receptors in the rat superior cervical ganglion. Brain Res 775:166-182
29. Parsons RL (2004) Mammalian cardiac ganglia as local integration centers: histochemical and electrophysiological evidence. In: Dun N, Machado B, Pilowsky P (eds) Mechanisms of cardiovascular regulation. Kluwer Academic Publishers, Norwell, pp 335-356
30. Randall WC, Wurster RD (1994) Peripheral innervation of the heart. In: Levy MN, Schwartz PJ (eds) Vagal control of the heart: experimental basis and clinical implications. Futura, Armonk, pp 21-32
31. Rechardt L, Aalto-Setala K, Purjeranta M, Pelto-Huikko M, Kyosola K (1986) Peptidegic innervation of human atrial myocardium: an electron microscopical and immunocytochemical study. J Auton Nerv Syst 17:21-32
32. Seabrook GR, Fieber LA, Adams DJ (1990) Neurotransmission in neonatal rat cardiac ganglion in situ. Am J Physiol 259:H997-H1005
33. Seebeck J, Schmidt WE, Kilbinger H, Neumann J, Zimmermann N, Herzig S (1996) PACAP induces bradycardia in guinea-pig heart by stimulation of atrial cholinergic neurones. Naunyn-Schmiedeberg's Arch Pharmacol 354:424-430
34. Steele PA, Gibbins IL, Morris JL, Mayer B (1994) Multiple populations of neuropeptide-containing intrinsic neurons in the guinea-pig heart. Neuroscience 62:241-250
35. Unwin RJ, Reed T, Thom S, Calam J, Peart WS (1987) Effects of indomethacin and (±)-propranolol on the cardiovascular and rennin responses to vasoactive intestinal polypeptide (VIP) infusion in man. Br J Clin Pharmacol 23:523-528
36. Vaudry D, Gonzalez BJ, Basille M, Yon L, Fournier A, Vaudry H (2000) Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions. Pharmacol Rev 52:269-324
37. Weihe E, Reinecke M, Forssmann WG (1984) Distribution of vasoactive intestinal polypeptide-like immunoreactivity in the mammalian heart. Interrelation with neurotensin- and substance P-like immunoreactive nerves. Cell Tissue Res 236:527-540