Cladobotric acids A-F: New cytotoxic polyketides from a New Zealand Cladobotryum sp.

Journal of Organic Chemistry

Volumn 71, Issue 2, 2006, Pages 492-497

  Mitova, Maya I ^a   Lang, Gerhard ^a   Blunt, John W ^a   Cummings, Nicholas J ^a   Cole, Anthony L J ^a   Robinson, Ward T ^a   Munro, Murray H G ^a  

^a UNIVERSITY OF CANTERBURY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CYTOLOGY; FERMENTATION; FUNGI; TOXICITY; X RAY CRYSTALLOGRAPHY;

BACILLUS SUBTILIS; CLADOBOTRIC ACIDS; LEUKEMIA CELL; POLYKETIDE CHAIN;

ORGANIC POLYMERS;

CLADOBOTRIC ACID; CLADOBOTRIC ACID A; CLADOBOTRIC ACID B; CLADOBOTRIC ACID C; CLADOBOTRIC ACID D; CLADOBOTRIC ACID E; CLADOBOTRIC ACID F; POLYKETIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIFUNGAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; CANDIDA ALBICANS; CLADOBOTRYUM; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; FUNGAL STRAIN; FUNGUS; ISOTOPE LABELING; LEUKEMIA CELL; MOUSE; NEW ZEALAND; NONHUMAN; SPECIES; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS; BOTRYTIS; LEUKEMIA P388; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NEW ZEALAND;

EID: 30744470663     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo051883l     Document Type: Article

References (16)

1. Rogerson, C. T.; Samuels, G. J. Mycologia 1993, 85, 231-272.
2. Feng, Y.; Blunt, J. W.; Cole, A. L. J.; Cannon, J. F.; Robinson, W. T.; Munro, M. H. G. J. Org. Chem. 2003, 68, 2002-2005.
3. Wagner, C.; Anke, H.; Besl, H.; Sterner, O. Z. Naturforsch., C: J. Biosci. 1995, 50, 358-364.
4. Breinholt, J.; Jensen, H. C.; Kjaer, A.; Olsen, C. E.; Rassing, B. R.; Rosendahl, C. N.; Sotofte, I. Acta Chem. Scand. 1998, 52, 631-634.
5. Sakemi, S.; Bordner, J.; DeCosta, D. L.; Dekker, K. A.; Hirai, H.; Inagaki, T.; Kim, Y.-J.; Kojima, N.; Sims, J. C.; Sugie, Y.; Sugiura, A.; Sutcliffe, J. A.; Tachikawa, K.; Truesdell, S. J.; Wong, J. W.; Yoshikawa, N.; Kojima, Y. J. Antibiot. 2002, 55, 6-18.
6. Sakamoto, K.; Tsujii, E.; Abe, F.; Nakanishi, T.; Yamashita, M.; Shigematsu, N.; Izumi, S.; Okuhara, M. J. Antibiot. 1996, 49, 37-44.
7. Hadden, C. E.; Martin, G. E.; Krishnamurthy, V. V. Magn. Reson. Chem. 2000, 38, 143-147.
8. Harris, G. H.; Dai, P. J. Liq. Chromatogr. Relat. Technol. 2001, 24, 1775-1790.
9. Breinholt, J.; Kjoer, A.; Olsen, C. E.; Rassing, B. R.; Rosendahl, C. N. Acta Chem. Scand. 1997, 51, 1241-1244.
10. Thomas, R. ChemBioChem 2001, 2, 612-627.
11. Alley, M. C.; Scudiero, D. A.; Monks, A.; Hursey, M. L.; Czerwinski, M. J.; Fine, D. L.; Abbott, B. J.; Mayo, J. G.; Shoemaker, R. H.; Boyd, M. R. Cancer Res. 1988, 48, 589-601.
12. Lorimer, S. D.; Barns, G.; Evans, A. C.; Foster, L. M.; May, B. C. H.; Perry, N. B.; Tangney, R. S. Phytomedicine 1996, 2, 327-333.
13. In the agar diffusion assay, the antimicrobial activity against all strains was measured as the radius of inhibition zone, excluding disc.
14. APEX IL User Manual; Bruket AXS, Inc.: Karlsruhe, Germany, 2005.
15. Sheldrick, G. M. SHELXTL Reference Manual, version 5; Siemens Energy and Automation, Inc.: Madison, WI, 1997.
16. Sheldrick, G. M. Acta Crystallogr., Sect. A: Found. Crystallogr. 1990, 46, 467-473.