Enhanced rate of ethanol elimination from blood after intravenous administration of amino acids compared with equicaloric glucose

Alcohol and Alcoholism

Volumn 41, Issue 1, 2006, Pages 39-43

  Lisander, Björn ^a   Lundvall, Olle ^a   Tomner, Jens ^a   Jones, Alan Wayne ^a  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; GLUCOSE; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RINGER ACETATE; VAMIN; VAMIN 18 G N/I;

ADULT; ALCOHOL BLOOD LEVEL; ALCOHOL METABOLISM; ANALYSIS OF VARIANCE; ARTICLE; BLOOD SAMPLING; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET RESTRICTION; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG MECHANISM; EXCRETION; GAS CHROMATOGRAPHY; GLUCOSE BLOOD LEVEL; HEART RATE; HUMAN; LIVER; MALE; MITOCHONDRION; OXYGEN CONSUMPTION; PATIENT MONITORING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; AMINO ACIDS; ANALYSIS OF VARIANCE; CHROMATOGRAPHY, GAS; CROSS-OVER STUDIES; ETHANOL; GLUCONEOGENESIS; GLUCOSE; HEART RATE; HUMANS; INJECTIONS, INTRAVENOUS; ISOTONIC SOLUTIONS; MALE; OXYGEN CONSUMPTION;

EID: 30744456262     PISSN: 07350414     EISSN: 14643502     Source Type: Journal    
DOI: 10.1093/alcalc/agh188     Document Type: Article

References (36)

1. Badawy, A. A. (1998) Stress, alcohol metabolism and burn injury. Alcohol and Alcoholism 33, 311-312.
2. Berman, P. A. M., Baumgarten, I. and Viljoen D. L. (2003) Effect of oral fructose on ethanol elimination from the bloodstream. South African Journal of Science 99, 47-50.
3. Bobyleva-Guarriero, V., Battelli, D., Bellei, M. et al. (1989) Sources of intra-mitochondrial malate. FASEB Journal 3, 2208-2211.
4. Braggins, T. J. and Crow, K. E. (1981) The effect of high ethanol doses on rates of ethanol oxidation in rats - a reassessment of factors controlling rates of ethanol oxidation in-vivo. European Journal of Biochemistry 119, 633-640.
5. Brown, J. A., Gore, D. C. and Jahoor, F. (1994) Catabolic hormones alone fail to reproduce the stress-induced efflux of amino acids. Archives of Surgery 129, 819-824.
6. Brown, S. S., Forrest, J. A. H. and Roscoe, P. (1972) A controlled trial of fructose in the treatment of acute alcoholic intoxication. Lancet ii, 898-900.
7. Brundin, T. and Wahren, J. (1994a) Effects of i.v. amino acids on human splanchnic and whole body oxygen consumption, blood flow, and blood temperatures. American Journal of Physiology 266, E396-E402.
8. Brundin, T. and Wahren, J. (1994b) Influence of protein ingestion on human splanchnic and whole-body oxygen consumption, blood flow, and blood temperature. Metabolism 43, 626-632.
9. Crow, K. E. and Hardman, M. J. (1989) Regulation of rates of ethanol metabolism. In Human Metabolism of Alcohol, Vol. II, Crow, K. E. and Batt, R. D. eds, pp. 3-16. CRC Press, Boca Raton.
10. Crow, K. E., Newland, K. M. and Batt, R. D. (1981) The fructose effect. New Zealand Medical Journal 93, 232-234.
11. Crowder, M. J. and Hand, D. J. (1993) Analysis of Repeated Measures. Chapman and Hall, London.
12. Crownover, B. P., La Dine, J., Bradford, B. et al. (1986) Activation of ethanol metabolism in humans by fructose: Importance of the experimental design. Journal of Pharmacology and Experimental Therapeutics 236, 574-579.
13. Demling, R. H. and Seigne, P. (2000) Metabolic management of patients with severe burns. World Journal of Surgery 24, 673-680.
14. Dolecek, R. (1989) Endocrine changes after burn trauma - a review. Keio Journal of Medicine 38, 262-276.
15. Dundee, J. W. (1972) Effect of fructose on blood-alcohol levels. Lancet ii, 1086.
16. Eggleton, M. G. (1940) Some factors affecting the metabolic rate of ethanol. Journal of Physiology 98, 239-254.
17. Eriksson, C. J. P. (2001) Role of acetaldehyde in the actions of ethanol (update 2000). Alcoholism: Clinical and Experimental Research 25, 15S-32S.
18. Herndon, D. N. and Tompkins, R. G. (2004) Support of the metabolic response to burn injury. Lancet 363, 1895-1901.
19. Jones, A. W., Jönsson, K. A. and Kechagias, S. (1997a) Effect of high-fat, high-protein, and high-carbohydrate meals on the pharmacokinetics of a small dose of ethanol. British Journal of Clinical Pharmacology 44, 521-526.
20. Jones, A. W., Zdolsek, H. J., Sjöberg, F. et al. (1997b) Accelerated metabolism of ethanol in patients with burn-injury. Alcohol and Alcoholism 32, 628-630.
21. Jones, A. W. and Schuberth, J. (1989) Computer-aided headspace gas chromatography applied to blood-alcohol analysis: Importance of online process control. Journal of Forensic Sciences 34, 1116-1127.
22. Jones, A. W. (2003) Disposition and fate of alcohol in the body. In Medical-Legal Aspects of Alcohol, 4th edn, Garriott, J. C. ed., pp. 47-112. Lawyers and Judges Publishing Company, Tuscon.
23. Li, J., Mills, T. and Erato, R. (1999) Intravenous saline has no effect on blood ethanol clearance. Journal of Emergency Medicine 17, 1-5.
24. Lumeng, L., Bosron, W. F. and Li, T. K. (1979) Quantitative correlation of ethanol elimination rates with liver alcohol dehydrogenase activities in fed, fasted and food-restricted rats. Biochemical Pharmacology 28, 1547-1551.
25. Mascord, D., Smith, J., Starmer, G. A. et al. (1988) Effect of oral glucose on the rate of metabolism of ethanol in humans. Alcohol and Alcoholism 23, 365-370.
26. Mezey, E. (1998) Stress and ethanol metabolism. Alcohol and Alcoholism 33, 310.
27. Newman, H. W. (1941) Acute Alcohol Intoxication. Stanford University Press, Stanford.
28. Plapp, B. V. (1975) Rate-limiting steps in ethanol metabolism and approaches to changing these rates biochemically. Advances in Experimental Medicine and Biology 56, 77-109.
29. Ramchandani, V. A., Kwo, P. Y. and Li, T. K. (2001) Effect of food and food composition on alcohol elimination rates in healthy men and women. Journal of Clinical Pharmacology 41, 1345-1350.
30. Rogers, J., Smith, J., Starmer, G. A. et al. (1987) Differing effects of carbohydrate, fat and protein on the rate of ethanol metabolism. Alcohol and Alcoholism 22, 345-353.
31. Selldén, E. and Lindahl, S. G. (1998) Amino acid-induced thermogenesis to prevent hypothermia during anesthesia is not associated with increased stress response. Anesthesia and Analgesia 87, 637-640.
32. Selldén, E., Bränström, R. and Brundin, T. (1996) Preoperative infusion of amino acids prevents postoperative hypothermia. British Journal of Anaesthesia 76, 227-234.
33. Thurman, R. B. and McKenna W. R. (1975) Pathways of ethanol metabolism in rat liver. Advances in Experimental Medicine and Biology 56, 57-76.
34. Tygstrup, N., Winkler, K. and Lundquist, F. (1965) The mechanism of the fructose effect on the ethanol metabolism of the human liver. Journal of Clinical Investigation 44, 817-830.
35. Wallgren, H. (1970) Absorption, diffusion, distribution and elimination of ethanol, effect on biological membranes. In: International Encyclopedia of Pharmacology and Therapeutics, Section 20, Vol. 1, Alcohols and Derivatives, Tremolieres, J, ed., pp. 161-188. Pergamon Press, Oxford.
36. Zdolsek, H. J., Sjöberg, F., Lisander, B. et al. (1999) The effect of hypermetabolism induced by burn trauma on the ethanol-oxidizing capacity of the liver. Critical Care Medicine 27, 2622-2625.