Role of aspartate 143 in Escherichia coli tRNA-guanine transglycosylase: Alteration of heterocyclic substrate specificity

Biochemistry

Volumn 45, Issue 2, 2006, Pages 617-625

  Todorov, Katherine Abold ^a,b   Garcia, George A ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTAGENESIS; RNA; SUBSTRATES; X RAY CRYSTALLOGRAPHY;

ANTICODON WOBBLE POSITIONS; ASPARTATE 143; HETEROCYCLIC SUBSTRATE RECOGNITION; TRNA-GUANINE TRANSGLYCOSYLASE; WATSON-CRICK BASE;

ESCHERICHIA COLI;

GLYCOSYLTRANSFERASE; GUANINE; HETEROCYCLIC COMPOUND; HYPOXANTHINE; QUEUINE; QUEUINE TRANSFER RIBONUCLEIC ACID RIBOSYLTRANSFERASE; TRANSFER RNA; UNCLASSIFIED DRUG; XANTHINE;

ANTICODON; ARTICLE; BASE PAIRING; COMPUTER MODEL; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; GENE MUTATION; GENETIC CODE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

AMINO ACID SUBSTITUTION; ANTICODON; ASPARTIC ACID; ESCHERICHIA COLI PROTEINS; HYPOXANTHINE; KINETICS; MUTATION; PENTOSYLTRANSFERASES; SERINE; SUBSTRATE SPECIFICITY; THREONINE; XANTHINE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 30744440069     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051863d     Document Type: Article

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