Conformational induction is the key process for activation of the AT 1 receptor

Biochemical Pharmacology

Volumn 71, Issue 4, 2006, Pages 464-471

  Ellis, James ^a,b   Warburton, Philip ^a   Donnelly, Dan ^a   Balmforth, Anthony J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

AT1 receptor; Conformational induction; Conformational selection; Constitutively active; Extended ternary complex model

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN II [3-8];

ARTICLE; BINDING AFFINITY; CONFORMATION; CONTROLLED STUDY; DRUG POTENCY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RECEPTOR BINDING; WILD TYPE;

ANGIOTENSIN II; BINDING, COMPETITIVE; CELL LINE; HUMANS; INOSITOL PHOSPHATES; MODELS, BIOLOGICAL; PROTEIN CONFORMATION; RECEPTOR, ANGIOTENSIN, TYPE 1; TIME FACTORS;

EID: 30444444077     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.11.011     Document Type: Article

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