메뉴 건너뛰기




Volumn 26, Issue 1, 2006, Pages 52-55

Newer aspects of carnitine metabolism in uremia

Author keywords

Carnitine; Carnitine acyltransferase; Carnitine deficiency; Hemodialysis; Mitochondria

Indexed keywords

CARNITINE; EMETINE; ERYTHROPOIETIN; HYDROCORTISONE; MUSCLE ENZYME; STATIN;

EID: 30444440888     PISSN: 02709295     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semnephrol.2005.06.010     Document Type: Article
Times cited : (5)

References (38)
  • 1
    • 4444311812 scopus 로고    scopus 로고
    • Carnitine acyltransferases and their influence on CoA pools in health and disease
    • R.R. Ramsay, V.A. Zammit Carnitine acyltransferases and their influence on CoA pools in health and disease Mol Aspects Med 25 2004 475 493
    • (2004) Mol Aspects Med , vol.25 , pp. 475-493
    • Ramsay, R.R.1    Zammit, V.A.2
  • 2
    • 0031043030 scopus 로고    scopus 로고
    • The mitochondrial carnitine palmitoyltransferase system. from concept to molecular analysis
    • J.D. McGarry, N.F. Brown The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis Eur J Biochem 244 1997 1 14
    • (1997) Eur J Biochem , vol.244 , pp. 1-14
    • McGarry, J.D.1    Brown, N.F.2
  • 3
    • 4444323965 scopus 로고    scopus 로고
    • Carnitine-acylcarnitine translocase deficiency, clinical, biochemical and genetic aspects
    • M.E. Rubio-Gozalbo, J.A. Bakker, H.R. Waterham Carnitine-acylcarnitine translocase deficiency, clinical, biochemical and genetic aspects Mol Aspects Med 25 2004 521 532
    • (2004) Mol Aspects Med , vol.25 , pp. 521-532
    • Rubio-Gozalbo, M.E.1    Bakker, J.A.2    Waterham, H.R.3
  • 4
    • 0035815991 scopus 로고    scopus 로고
    • Na(+)-coupled transport of L-carnitine via high-affinity carnitine transporter OCTN2 and its subcellular localization in kidney
    • I. Tamai, K. China, Y. Sai Na(+)-coupled transport of L-carnitine via high-affinity carnitine transporter OCTN2 and its subcellular localization in kidney Biochim Biophys Acta 1512 2001 273 284
    • (2001) Biochim Biophys Acta , vol.1512 , pp. 273-284
    • Tamai, I.1    China, K.2    Sai, Y.3
  • 5
    • 0002632388 scopus 로고    scopus 로고
    • The role of carnitine in cell metabolism
    • C. de Simone G. Famularo Springer-Verlag Heidelberg
    • J. Bremer The role of carnitine in cell metabolism C. de Simone G. Famularo Carnitine Today 1997 Springer-Verlag Heidelberg
    • (1997) Carnitine Today
    • Bremer, J.1
  • 6
    • 0031797265 scopus 로고    scopus 로고
    • Role of acetyl-L-carnitine in rat brain lipogenesis: Implications for polyunsaturated fatty acid biosynthesis
    • R. Ricciolini, M. Scalibastri, J.K. Kelleher Role of acetyl-L-carnitine in rat brain lipogenesis Implications for polyunsaturated fatty acid biosynthesis J Neurochem 71 1998 2510 2517
    • (1998) J Neurochem , vol.71 , pp. 2510-2517
    • Ricciolini, R.1    Scalibastri, M.2    Kelleher, J.K.3
  • 7
    • 0002451854 scopus 로고
    • Comparative aspects of carnitine biosynthesis in microorganism and mammals with attention to carnitine biosynthesis in man
    • R.A. Frenkel J.D. McGarry Academic Press New York
    • C.J. Rebouche Comparative aspects of carnitine biosynthesis in microorganism and mammals with attention to carnitine biosynthesis in man R.A. Frenkel J.D. McGarry Carnitine Biosynthesis, Metabolism and Functions 1980 Academic Press New York 57 72
    • (1980) Carnitine Biosynthesis, Metabolism and Functions , pp. 57-72
    • Rebouche, C.J.1
  • 8
    • 0027049235 scopus 로고
    • Carnitine function and requirements during the life cycle
    • C.J. Rebouche Carnitine function and requirements during the life cycle FASEB J 6 1992 3379 3386
    • (1992) FASEB J , vol.6 , pp. 3379-3386
    • Rebouche, C.J.1
  • 9
    • 0031868466 scopus 로고    scopus 로고
    • Genetic disorders of carnitine metabolism and their nutritional management
    • J. Kerner, C. Hoppel Genetic disorders of carnitine metabolism and their nutritional management Annu Rev Nutr 18 1998 179 206
    • (1998) Annu Rev Nutr , vol.18 , pp. 179-206
    • Kerner, J.1    Hoppel, C.2
  • 10
    • 0038042472 scopus 로고    scopus 로고
    • Treatment of carnitine deficiency
    • S. Winter Treatment of carnitine deficiency J Inherit Metab Dis 26 2-3 2003 171 181
    • (2003) J Inherit Metab Dis , vol.26 , Issue.2-3 , pp. 171-181
    • Winter, S.1
  • 11
    • 0037379698 scopus 로고    scopus 로고
    • Dialysis-related carnitine disorder and levocarnitine pharmacology
    • A.M. Evans Dialysis-related carnitine disorder and levocarnitine pharmacology Am J Kidney Dis 41 suppl 4 2003 S13 S26
    • (2003) Am J Kidney Dis , vol.41 , Issue.4 SUPPL.
    • Evans, A.M.1
  • 13
    • 0023771024 scopus 로고    scopus 로고
    • Carnitine abnormalities in patients with renal insufficiency. Pathophysiological and therapeutical aspect
    • C. Wanner, W.H. Horl Carnitine abnormalities in patients with renal insufficiency. Pathophysiological and therapeutical aspect Nephron 50 1998 89 102
    • (1998) Nephron , vol.50 , pp. 89-102
    • Wanner, C.1    Horl, W.H.2
  • 14
    • 0020553096 scopus 로고
    • Plasma and muscle carnitine levels in hemodialysis patients with morphological-ultrastructural examination of muscle samples
    • V. Savica, G. Bellinghieri, C. Di Stefano Plasma and muscle carnitine levels in hemodialysis patients with morphological-ultrastructural examination of muscle samples Nephron 35 1983 232 236
    • (1983) Nephron , vol.35 , pp. 232-236
    • Savica, V.1    Bellinghieri, G.2    Di Stefano, C.3
  • 15
    • 0031133702 scopus 로고
    • Carnitine and lipid profile in uremia
    • V. Savica, G. Bellinghieri Carnitine and lipid profile in uremia Clin Ter 148 1977 229 236
    • (1977) Clin Ter , vol.148 , pp. 229-236
    • Savica, V.1    Bellinghieri, G.2
  • 16
    • 5444257488 scopus 로고    scopus 로고
    • Carnitine system in uremic patients: Molecular and clinical aspects
    • V. Savica, M. Calvani, P. Benatti Carnitine system in uremic patients Molecular and clinical aspects Semin Nephrol 24 5 2004 464 468
    • (2004) Semin Nephrol , vol.24 , Issue.5 , pp. 464-468
    • Savica, V.1    Calvani, M.2    Benatti, P.3
  • 17
    • 0032696186 scopus 로고    scopus 로고
    • Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): Its pharmacological and toxicological relevance
    • R. Ohashi, I. Tamai, H. Yabuuchi Na(+)-dependent carnitine transport by organic cation transporter (OCTN2) Its pharmacological and toxicological relevance J Pharmacol Exp Ther 292 1999 778 784
    • (1999) J Pharmacol Exp Ther , vol.292 , pp. 778-784
    • Ohashi, R.1    Tamai, I.2    Yabuuchi, H.3
  • 18
    • 0029791338 scopus 로고    scopus 로고
    • The effects of 3-hydroxy-3-methylglutaryl-CoA reductase inhibition on tissue levels of carnitine and carnitine acyltransferase activity in the rabbit
    • J. Bhuiyan, D.W. Seccombe The effects of 3-hydroxy-3-methylglutaryl-CoA reductase inhibition on tissue levels of carnitine and carnitine acyltransferase activity in the rabbit Lipids 31 1996 867 870
    • (1996) Lipids , vol.31 , pp. 867-870
    • Bhuiyan, J.1    Seccombe, D.W.2
  • 19
    • 0022458656 scopus 로고
    • Carnitine status, plasma lipid profiles, and exercise capacity of dialysis patients: Effects of a submaximal exercise program
    • D.L. Lennon, E. Shrago, M. Madden Carnitine status, plasma lipid profiles, and exercise capacity of dialysis patients Effects of a submaximal exercise program Metabolism 35 1986 728 735
    • (1986) Metabolism , vol.35 , pp. 728-735
    • Lennon, D.L.1    Shrago, E.2    Madden, M.3
  • 20
    • 0030058123 scopus 로고    scopus 로고
    • Reduced carnitine palmitoyl transferase activity and altered acyl-trafficking in red blood cells from hemodialysis patients
    • B. De los Reyes, R. Perez-Garcia, A. Liras Reduced carnitine palmitoyl transferase activity and altered acyl-trafficking in red blood cells from hemodialysis patients Biochim Biophys Acta 1315 1996 37 39
    • (1996) Biochim Biophys Acta , vol.1315 , pp. 37-39
    • De Los Reyes, B.1    Perez-Garcia, R.2    Liras, A.3
  • 21
    • 0346788905 scopus 로고    scopus 로고
    • Myocardial carnitine palmitoyltransferase I as a target for oxidative modification in inflammation and sepsis
    • S. Eaton, K. Fukumoto, G. Stefanutti Myocardial carnitine palmitoyltransferase I as a target for oxidative modification in inflammation and sepsis Biochem Soc Trans 31 2003 1133 1136
    • (2003) Biochem Soc Trans , vol.31 , pp. 1133-1136
    • Eaton, S.1    Fukumoto, K.2    Stefanutti, G.3
  • 22
    • 0037636366 scopus 로고    scopus 로고
    • The physiology of cellular liporegulation
    • R.H. Unger The physiology of cellular liporegulation Annu Rev Physiol 65 2003 333 347
    • (2003) Annu Rev Physiol , vol.65 , pp. 333-347
    • Unger, R.H.1
  • 23
    • 0142204338 scopus 로고    scopus 로고
    • Decreased mitochondrial carnitine translocase in skeletal muscles impairs utilization of fatty acids in insulin-resistant patients
    • G. Peluso, O. Petillo, S. Margarucci Decreased mitochondrial carnitine translocase in skeletal muscles impairs utilization of fatty acids in insulin-resistant patients Front Biosci 7 2002 a109 a116
    • (2002) Front Biosci , vol.7
    • Peluso, G.1    Petillo, O.2    Margarucci, S.3
  • 24
    • 13144307082 scopus 로고    scopus 로고
    • Effects of L-carnitine supplementation on muscular symptoms in hemodialyzed patients
    • Y. Sakurauchi, Y. Matsumoto, T. Shinzato Effects of L-carnitine supplementation on muscular symptoms in hemodialyzed patients Am J Kidney Dis 32 1998 258 264
    • (1998) Am J Kidney Dis , vol.32 , pp. 258-264
    • Sakurauchi, Y.1    Matsumoto, Y.2    Shinzato, T.3
  • 25
    • 0031300070 scopus 로고    scopus 로고
    • Low carnitine levels in hemodialysis patients: Relationship with functional activity status and intra-dialytic hypotension
    • S. Riley, S. Rutherford, P.A. Rutherford Low carnitine levels in hemodialysis patients Relationship with functional activity status and intra-dialytic hypotension Clin Nephrol 48 1997 392 393
    • (1997) Clin Nephrol , vol.48 , pp. 392-393
    • Riley, S.1    Rutherford, S.2    Rutherford, P.A.3
  • 26
    • 1242342233 scopus 로고    scopus 로고
    • Serum carnitine concentrations correlated to clinical outcome parameters in chronic hemodialysis patients
    • A.L. Steiber, L.J. Weatherspoon, L. Spry Serum carnitine concentrations correlated to clinical outcome parameters in chronic hemodialysis patients Clin Nutr 23 2004 27 34
    • (2004) Clin Nutr , vol.23 , pp. 27-34
    • Steiber, A.L.1    Weatherspoon, L.J.2    Spry, L.3
  • 27
    • 0026653971 scopus 로고
    • Carnitine metabolism during exercise in patients on chronic hemodialysis
    • W.R. Hiatt, B.J. Koziol, J.I. Shapiro Carnitine metabolism during exercise in patients on chronic hemodialysis Kidney Int 41 1992 1613 1619
    • (1992) Kidney Int , vol.41 , pp. 1613-1619
    • Hiatt, W.R.1    Koziol, B.J.2    Shapiro, J.I.3
  • 28
    • 0025255292 scopus 로고
    • Morphometric evidence of the trophic effect of L-carnitine on human skeletal muscle
    • L.G. Spagnoli, G. Palmieri, A. Mauriello Morphometric evidence of the trophic effect of L-carnitine on human skeletal muscle Nephron 55 1990 16 23
    • (1990) Nephron , vol.55 , pp. 16-23
    • Spagnoli, L.G.1    Palmieri, G.2    Mauriello, A.3
  • 29
    • 0021040155 scopus 로고
    • The role of L-carnitine in the pathogenesis of cardiomegaly in patients with chronic hemodialysis
    • Y. Kudoh, T. Shoji, H. Oimatsu The role of L-carnitine in the pathogenesis of cardiomegaly in patients with chronic hemodialysis Jpn Circ J 47 1983 1391 1397
    • (1983) Jpn Circ J , vol.47 , pp. 1391-1397
    • Kudoh, Y.1    Shoji, T.2    Oimatsu, H.3
  • 30
    • 0027016498 scopus 로고
    • Amelioration of cardiac function by L-carnitine administration in patients on hemodialysis
    • E.S.A. Van, F.G. Henny, M.P. Kooistra Amelioration of cardiac function by L-carnitine administration in patients on hemodialysis Contrib Nephrol 98 1992 28 35
    • (1992) Contrib Nephrol , vol.98 , pp. 28-35
    • Van, E.S.A.1    Henny, F.G.2    Kooistra, M.P.3
  • 31
    • 0029922109 scopus 로고    scopus 로고
    • Correlation between serum carnitine levels and erythrocyte osmotic fragility in hemodialysis patients
    • M. Matsumura, S. Hatakeyama, I. Koni Correlation between serum carnitine levels and erythrocyte osmotic fragility in hemodialysis patients Nephron 72 1996 574 578
    • (1996) Nephron , vol.72 , pp. 574-578
    • Matsumura, M.1    Hatakeyama, S.2    Koni, I.3
  • 32
    • 0026025190 scopus 로고
    • The response to recombinant human erythropoietin in patients with the anemia of end-stage renal disease is correlated with serum carnitine levels
    • M.P. Kooistra, A. Struyvenberg, E.S.A. van The response to recombinant human erythropoietin in patients with the anemia of end-stage renal disease is correlated with serum carnitine levels Nephron 57 1991 127 128
    • (1991) Nephron , vol.57 , pp. 127-128
    • Kooistra, M.P.1    Struyvenberg, A.2    Van, E.S.A.3
  • 33
    • 12244254419 scopus 로고    scopus 로고
    • National Kidney Foundation Carnitine Consensus Conference. Practice recommendations for the use of L-carnitine in dialysis-related carnitine disorder. National Kidney Foundation Carnitine Consensus Conference
    • G. Eknoyan, D.L. Latos, J. Lindberg National Kidney Foundation Carnitine Consensus Conference. Practice recommendations for the use of L-carnitine in dialysis-related carnitine disorder. National Kidney Foundation Carnitine Consensus Conference Am J Kidney Dis 41 2003 868 876
    • (2003) Am J Kidney Dis , vol.41 , pp. 868-876
    • Eknoyan, G.1    Latos, D.L.2    Lindberg, J.3
  • 34
    • 0032913808 scopus 로고    scopus 로고
    • Anemia and carnitine supplementation in hemodialyzed patients
    • J. Kletzmayr, G. Mayer, E. Legenstein Anemia and carnitine supplementation in hemodialyzed patients Kidney Int Suppl 69 1999 S93 S106
    • (1999) Kidney Int Suppl , vol.69
    • Kletzmayr, J.1    Mayer, G.2    Legenstein, E.3
  • 35
    • 0035994250 scopus 로고    scopus 로고
    • The influence of l-carnitine supplementation on hematocrit and hemoglobin levels in patients with end stage renal failure on CAPD
    • N. Sotirakopoulos, G. Athanasiou, T. Tsitsios The influence of l-carnitine supplementation on hematocrit and hemoglobin levels in patients with end stage renal failure on CAPD Ren Fail 24 2002 505 510
    • (2002) Ren Fail , vol.24 , pp. 505-510
    • Sotirakopoulos, N.1    Athanasiou, G.2    Tsitsios, T.3
  • 37
    • 0035991593 scopus 로고    scopus 로고
    • Beneficial effects of L-carnitine in dialysis patients with impaired left ventricular function: An observational study
    • G.F. Romagnoli, A. Naso, G. Carraro Beneficial effects of L-carnitine in dialysis patients with impaired left ventricular function An observational study Curr Med Res Opin 18 2002 172 175
    • (2002) Curr Med Res Opin , vol.18 , pp. 172-175
    • Romagnoli, G.F.1    Naso, A.2    Carraro, G.3
  • 38
    • 11844262893 scopus 로고    scopus 로고
    • L-carnitine infusions may suppress serum C-reactive protein and improve nutritional status in maintenance hemodialysis patients
    • V. Savica, D. Santoro, F. Ciolino L-carnitine infusions may suppress serum C-reactive protein and improve nutritional status in maintenance hemodialysis patients J Ren Nutr 2005 225 230 15 No 2 (April)
    • (2005) J Ren Nutr , pp. 225-230
    • Savica, V.1    Santoro, D.2    Ciolino, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.