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Volumn 830, Issue 2, 2006, Pages 314-321
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Sensitive method for the quantitative determination of proguanil and its metabolites in rat blood and plasma by liquid chromatography-mass spectrometry
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Author keywords
Antimalarial; Blood and plasma assay; Cycloguanil; LC MS; Proguanil
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Indexed keywords
ASSAYS;
BLOOD;
LIQUID CHROMATOGRAPHY;
MASS SPECTROMETRY;
SENSITIVITY ANALYSIS;
ANTIMALARIAL;
BLOOD AND PLASMA ASSAY;
CYCLOGUANIL;
LC-MS;
PROGUANIL;
METABOLITES;
1 (4 CHLOROPHENYL)BIGUANIDE;
ACETONITRILE;
BIGUANIDE DERIVATIVE;
CHLOROPROGUANIL;
CYCLOGUANIL;
DRUG METABOLITE;
FORMIC ACID;
PROGUANIL;
UNCLASSIFIED DRUG;
ACCURACY;
ANIMAL EXPERIMENT;
ARTICLE;
CONTROLLED STUDY;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
DRUG METABOLISM;
DRUG STRUCTURE;
ELECTROSPRAY MASS SPECTROMETRY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
NONHUMAN;
PLASMA;
PRIORITY JOURNAL;
QUADRUPOLE MASS SPECTROMETRY;
QUANTITATIVE ANALYSIS;
RAT;
TANDEM MASS SPECTROMETRY;
ADMINISTRATION, ORAL;
ANIMALS;
ANTIMALARIALS;
BIGUANIDES;
CALIBRATION;
CHLOROGUANIDE;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DRUG STABILITY;
FREEZING;
INJECTIONS, INTRAVENOUS;
RATS;
RATS, SPRAGUE-DAWLEY;
REPRODUCIBILITY OF RESULTS;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
TRIAZINES;
ANIMALIA;
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EID: 30444434399
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2005.11.004 Document Type: Article |
Times cited : (12)
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References (13)
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